Clinical trials: Drug Related Problems
Chronic Disease
Cost-benefit Analysis of a Clinical Pharmacist Intervention
Clinical pharmacy services are vital in the prevention of adverse drug events (ADEs) in clinical practice, extending beyond the hospital to chronic disease management in outpatient settings.
- Trial name
- NCT03803033
- Testing
- Clinical pharmacy-based home medication management review service
- Where
- Jordan
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Polypharmacy (People Under Treatment With 5 or More Drugs), Polypharmacy, Decision-making
Factors Determining the Rate of Adoption of Pharmaceutical Recommendations by Patients in Primary Care Following a Medication Review by a Pharmacist
Polypharmacy is a growing public health concern associated with adverse drug events, drug interactions, and hospitalizations. Medication reviews (MedRev) are structured evaluations of patients' medications aiming to optimize…
- Conditions
- Polypharmacy (People Under Treatment With 5 or More Drugs), Polypharmacy, Decision-making, Medication Review
- Trial name
- REVMedAdopt (NCT07606716)
- Testing
- medication review and deprescribing
- Where
- Belgium
- Volunteers
- 123 people
- Sponsor
- Université Catholique de Louvain
Ageing
The OMAGE (Optimization of Medication in AGEd) Transitional Care-Pathway: Impact on Readmissions
Background : The transitional care OMAGE-P combines three best practices recommendations from the French National Authority for Health (HAS) (i) a comprehensive review of diagnosis and treatments (ii) a standardized medical…
- Trial name
- OMAGE-P (NCT02657642)
- Volunteers
- 484 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Drug Related Problems Post Hospital Discharge, Healthcare Utilization
Drug-Related Problems and Healthcare Utilization Post-Hospital Discharge
The goal of this study is to investigate whether pharmacist provided counseling and medication dispensing at the patient's bedside can provide better outcomes than the current discharge process at Duke University Hospital.
- Conditions
- Drug Related Problems Post Hospital Discharge, Healthcare Utilization, Discharge Medication Counseling
- Trial name
- NCT01806038
- Testing
- RPh Counseling + Outpatient Med Dispensing at Discharge, Discharge Med Dispensing Plus Counseling - Current Practice
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Duke University
Intimate Partner Violence Against Women, Alcohol Abuse
Motivational Strategies in Batterer Intervention Programs for Offenders With Alcohol/Drug Abuse Problems (IMP-ADAPs)
Alcohol and/or drug abuse problems (ADAPs) have been consistently identified in the scientific literature as a risk factor of intimate partner violence against women (IPVAW).
- Conditions
- Intimate Partner Violence Against Women, Alcohol Abuse, Drug Abuse
- Trial name
- IMP-ADAPs (NCT03885349)
- Testing
- SBIP+ ADAPs-IMP, SBIP+IMP
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Valencia
Alcohol-Related Disorders, Alcohol Problem
Identifying and Managing Alcohol-related Health Problems in General Practice
The overall purpose of the proposed research is to increase patients' and general practitioners' (GPs') awareness of alcohol as a relevant factor for a wide variety of health problems in general practice, and enable earlier help…
- Conditions
- Alcohol-Related Disorders, Alcohol Problem, Alcohol Drug Interaction, Alcohol Use Disorder
- Trial name
- NCT04725552
- Testing
- 'Change' - an e-health intervention
- Where
- 4 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Stavanger HF
Cancer
Impact of the DROP Program on the DRP (Drug Related Problems) Related to Oral Anticancer Drugs in Ambulatory Patients with Risk Factors
The rise of oral anticancer drugs favors outpatient care but exposes patients to new risks compared to injectable chemotherapy at hospital: non-adherence to treatment, inappropriate management of side effects and interactions…
- Trial name
- DROP-SFPO (NCT03257969)
- Testing
- The DROP program of pharmaceutical interventions, Standard of care
- Where
- France
- Volunteers
- 248 people
- Sponsor
- Hospices Civils de Lyon
Drug Related Problems Associated Hospitalizations
Monitoring the Prevalence of E.R Admissions and Hospitalizations as a Result of Drug Related Problems (DRPs)
To research the prevalence and nature of DRP (Drug Related Problems) associated hospitalizations (hospitalizations due to problems\adverse effects of the medication treatment) .
- Trial name
- NCT01223950
- Volunteers
- 12,350 people
- Sponsor
- Hillel Yaffe Medical Center
Intravenous Drug Abuse, HIV Infections
Reducing Health Problems Associated With Injection Drug Use
The purpose of this study is to develop and test an intervention to reduce bacterial and viral infections among injection drug users.
- Trial name
- NCT01128920
- Testing
- Skin and Needle Hygiene Intervention, No intervention - assessment-only condition
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
Renal Failure Chronic Requiring Hemodialysis
Efficacy Study of Pharmacist Intervention on Medication-related Problems in Hemodialysis Patients
The investigators propose that pharmacist interventions would reduce the amount of unresolved medication-related problems in hemodialysis patients.
- Trial name
- NCT01356563
- Testing
- pharmaceutical care
- Where
- 2 sites in Taiwan
- Volunteers
- 150 people
- Sponsor
- Sin-Lau Hospital
Depression, Bipolar Affective Disorder
The Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Patients With Mental Disorders and Sleep Problems
The aim of this study is to examine the effect of a non-pharmacological transdiagnostic sleep intervention as add on to standard treatment for bipolar disorder, depression and attention deficit disorder.
- Conditions
- Depression, Bipolar Affective Disorder, Attention Deficit Disorder
- Trial name
- NCT05406414
- Testing
- Transdiagnostic sleep and circadian treatment, Active waitlist control group
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- University of Aarhus
Frailty, Emergency Department Visit
Association Between Geriatric Frailty and Medication Related Problems in the Emergency Department to Help Clinical Pharmacists Prioritise Patients
The healthcare systems are under increasing pressure due to a rise in emergency consultations, staff shortages, an ageing population and rising costs.
- Conditions
- Frailty, Emergency Department Visit, Elderly, Drug Drug Interaction
- Trial name
- DISARMED (NCT07282379)
- Testing
- Pharmaceutical analysis based on the Electronic Patient Record
- Where
- Switzerland
- Volunteers
- 300 people
- Sponsor
- Pharmacie des Hopitaux de l'Est Lemanique
Polypharmacy Patients
Assessment of a Novel Algorithm System for Polypharmacy Patient Medication Safety and Consultation
The aim of this study is to determine if insights based on the analysis of historical data of multidrug patients' electronic health records, by a novel system and algorithm, is noninferior to a clinical pharmacist analysis and…
- Trial name
- NCT05589870
- Testing
- Multi-drug analysis of polypharmacy treatment
- Where
- Israel
- Volunteers
- 91 people
- Sponsor
- MDI Health
Neoplasm
Role of the Pharmacist in Detection of Drug Interactions Before Antitumor Treatment Initiation
The purpose of this observational study is to evaluate the benefits of a pharmacist integration in an oncology ambulatory center, to prevent drug related problems (in particular drug drug interactions) at antitumor treatment…
- Trial name
- CHOPIN (NCT04142567)
- Where
- France
- Volunteers
- 440 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Schizophrenia
The Compliance Project Concerning People With Schizophrenia
The purpose of this study is to determine whether individual and/ or system orientated interventions can help the problem of people with schizophrenia dropping out of their drug treatment
- Trial name
- NCT00497848
- Testing
- motivational interviewing, The System-Orientated Intervention
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Ministry of the Interior and Health, Denmark
Adverse Drug Events
Drug-Related Problems : Focus on Age and Diabetes
Drug-Related Problems (DRP) are a variety of events or circumstances that can interfere with the expected results of a treatment.
- Trial name
- DRP-AD (NCT04692220)
- Testing
- Detection of Adverse Drug Events or Drug-Related Problems
- Where
- France
- Volunteers
- 27,000 people
- Sponsor
- University Hospital, Montpellier
Mental Health Services
Pharmaceutical Care and Quality of Life in Conditions Related to Psychotropic Drug Use
This study aims to assess and describe the impact of pharmaceutical care on identified drug-related problems (DRPs) in subjects using psycholeptics and psychoanaleptics in primary care, improving subjects' self-assessed quality…
- Trial name
- NCT06889636
- Testing
- Pharmaceutical care in solving drug-related problems in subjects using psychotropic medicines based on standardized protocol.., Common pharmacists' practice in Croatia.
- Where
- Croatia
- Volunteers
- 97 people
- Sponsor
- University of Rijeka
Substance Use Disorders
Treatment for Psychological and Drug Abuse Problems
The purpose of the study is to evaluate methods to help people in substance abuse treatment receive better psychiatric care. Patients enrolled in the study will be offered three months of standard psychiatric treatment, which…
- Trial name
- NCT01140334
- Testing
- Voucher Reinforcement, Standard Control
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Johns Hopkins University
Contrast Enhancement in Magnetic Resonance Imaging, Central Nervous System Pathology
A Study to Compare How Well Gadoquatrane Works and Its Safety With an Already Available Contrast Agent for MRI in People With Known or Suspected Brain or Spinal Cord-related Problems
Researchers are looking for a better way to help people with known or suspected brain or spinal cord-related problems scheduled for a "contrast-enhanced" Magnetic Resonance Imaging (MRI).
- Trial name
- Quanti CNS (NCT05915702)
- Testing
- Gadoquatrane (BAY1747846), Gadobutrol, Gadoterate meglumine
- Where
- 78 sites in United States, Argentina and 13 more
- Volunteers
- 321 people
- Sponsor
- Bayer
Medication-related Problems, Self-reported Medication Adherence
Improving Medication Therapy Through a Digital Interdisciplinary Medicine Therapy Optimisation Model
In this study, a telepharmacy service in primary care for home-living older adults in Northern Sweden's rural areas will be developed and evaluated.
- Conditions
- Medication-related Problems, Self-reported Medication Adherence, Health-related Quality of Life, Beliefs About Medicines
- Trial name
- MTO (NCT05629936)
- Testing
- Telepharmacy service
- Where
- 2 sites in Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Umeå University