Clinical trials: Drug Use
Alcohol Use Disorder
Probenecid as Medication for Alcohol Use Disorder (PROB)
The design is a randomized, within-subject, crossover, double-blind, placebo-controlled human alcohol laboratory study with one oral dose of 2g probenecid or placebo administered in two laboratory sessions.
- Trial name
- PROB (NCT04218357)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Brown University
Type 2 Diabetes Mellitus
Specified Drug-Use Survey of Alogliptin and Metformin Hydrochloride Combination Tablets "Survey on Long-term Use in Type 2 Diabetes Mellitus Patients With Renal or Hepatic Impairment or Advanced Age"
The purpose of this survey is to evaluate the long-term safety and efficacy of the alogliptin and metformin hydrochloride combination tablet in type 2 diabetes mellitus patients with renal impairment (mild), hepatic impairment…
- Trial name
- NCT03555565
- Testing
- Alogliptin and Metformin hydrochloride
- Where
- Japan
- Volunteers
- 1,026 people
- Sponsor
- Takeda
Infants
Prevenar (13v) Infant Drug Use Investigation
The purpose of this study is to investigate post marketing use and safety of Prevnar ( 13v) in infants vaccinated for the first time at the age of 2 months, inclusive, to 7 months, exclusive.
- Trial name
- NCT02119104
- Testing
- Prevenar (13v)
- Volunteers
- 1,087 people
- Sponsor
- Pfizer
Therapeutic Adherence and Compliance
Use of Antiretroviral (ARV) Drug Levels in Dried Blood Spots (DBS) to Assess and Manage ART Adherence in South Africa
This is a prospective, pilot study of HIV-positive individuals who have been on tenofovir-containing antiretroviral therapy for at least 4 months.
- Trial name
- ADD-ART (NCT04333498)
- Testing
- Feedback on DBS Concentrations
- Where
- 2 sites in United States, South Africa
- Volunteers
- 60 people
- Sponsor
- New York State Psychiatric Institute
HIV Infections, Drug Use
INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit
The purpose of this study is to determine the efficacy of using a mobile health delivery unit ("mobile unit") to deliver "one stop" integrated health services - particularly medication for opioid use disorder (MOUD) and…
- Conditions
- HIV Infections, Drug Use, Opioid Use, Opioid-use Disorder
- Trial name
- INTEGRA (NCT04804072)
- Testing
- Medication for opioid-use disorder (MOUD) for opioid-use disorder (OUD), HIV testing, HIV treatment for participants living with HIV not already in care
- Where
- 5 sites in United States
- Volunteers
- 447 people
- Sponsor
- HIV Prevention Trials Network
Smoking, Tobacco Product
Japanese Post-Market Cohort Study
The objectives and endpoints of this study were analyzed in the study population of adults eligible to purchase tobacco products.
- Trial name
- NCT03020667
- Where
- Japan
- Volunteers
- 1,124 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Advanced or Recurrent Colorectal Cancer
Panitumumab for Intravenous Infusion 100 mg and 400 mg Special Drug Use Surveillance "Survey on Unresectable, Advanced or Recurrent Colorectal Cancer With Wild-type KRAS Gene" (All-patient Surveillance)
The efficacy and safety of panitumumab (Vectibix) in the routine clinical setting will be studied. Specifically, information will be collected on the following as events of interest: skin disorders, interstitial lung disease…
- Trial name
- NCT02089737
- Testing
- Panitumumab
- Volunteers
- 3,091 people
- Sponsor
- Takeda
Smoking, Nicotine Dependence
A Trial of E-cigarettes in Current Cigarette Smokers
The purpose of this study is to examine cigarette smokers' use of electronic cigarettes (e-cigarettes), and how use of e-cigarettes affects short term smoking behavior.
- Conditions
- Smoking, Nicotine Dependence, Nicotine Dependence, Other Tobacco Product
- Trial name
- NCT02357173
- Testing
- electronic cigarette, cigarette group
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Medical University of South Carolina
Hemorrhage
All-Case Surveillance of Prizbind®
To evaluate safety and effectiveness of Prizbind® for Intravenous Solution 2.5 g under Japanese clinical condition.
- Trial name
- NCT02946931
- Testing
- Prizbind®
- Where
- Japan
- Volunteers
- 1,402 people
- Sponsor
- Boehringer Ingelheim
Cocaine Use Disorder
Drug Interaction and Self Administration Studies of Compounds for Cocaine Use Disorder
The overall goal of this project is to develop initial human data on effects of novel compounds on safety (interactions with cocaine) and efficacy (subjective response to cocaine and self administration data) in non-treatment…
- Trial name
- NCT02537873
- Testing
- Lorcaserin, Cocaine Intravenous (IV)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Virginia Commonwealth University
Cannabis-use Disorders
Behavioral Effects of Pregabalin and Cannabis
Cannabis is the most commonly used illicit drug in the United States, and its use is associated with rates of development of abuse and dependence, treatment admission and relapse that are comparable to other illicit drugs.
- Trial name
- NCT01511640
- Testing
- Pregabalin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Joshua A. Lile, Ph.D.
Systemic Mycosis
Voriconazole (Vfend) Drug Use Investigation (Regulatory Post Marketing Commitment Plan)
To collect the efficacy and safety informations of voriconazole related to their appropriate use in daily practice.
- Trial name
- NCT01151085
- Testing
- Voriconazole
- Volunteers
- 1,002 people
- Sponsor
- Pfizer
Substance Use Disorders, Overdose
Project POINT: Effectiveness and Scalability of an Overdose Survivor Intervention
The investigators seek to assess the effectiveness of Project POINT (Planned Outreach, Intervention, Naloxone, and Treatment). As originated in Indianapolis, Project POINT is a collaboration between Indianapolis Emergency Medical…
- Trial name
- POINT (NCT03336268)
- Testing
- POINT
- Where
- 2 sites in United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Indiana University