Clinical trials: Drug Users
Substance Use Disorders, Overdose
Emergency Medicine Peer Outreach Worker Engagement for Recovery
This is an observational, prospective case-control study evaluating the effects of an emergency department community health worker-peer recovery specialist program (PCHW), the Substance Misuse Assistance Response Team (SMART).
- Conditions
- Substance Use Disorders, Overdose, Opioid Use Disorder, Alcohol Use Disorder
- Trial name
- EMPOWER (NCT06320015)
- Testing
- Substance Misuse Assistance Response Team (SMART), Usual Care Group
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Drug Abuse, Healthy
Study in Healthy Recreational Polydrug Users to Measure the Abuse Potential of TC-5214
This is a single dose, crossover study to assess the abuse potential of TC-5214 compared to placebo, ketamine, and phentermine in healthy recreational polydrug users.
- Trial name
- TC-5214 (NCT01500018)
- Testing
- TC-5214, Ketamine, Phentermine
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Hepatitis C
Ask a Friend to Take a Test for Hepatitis C Infection
This exploratory study will carry out a respondent-driven sampling exercise, where participants will identify their previous injecting partners and contact these individuals to invite them to take an Hepatitis C test.
- Trial name
- NCT03697135
- Testing
- Respondent Driven Sampling
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- NHS Tayside
Medication Adherence, High Blood Pressure
Social Forces to Improve Statin Adherence (Study A)
To assess the effectiveness of reporting statin adherence patterns to a Medication Adherence Partner (MAP) in improving the outcome of statin adherence versus usual care as measured by an electronic pill bottle.
- Conditions
- Medication Adherence, High Blood Pressure, Diabetes
- Trial name
- NCT02018809
- Testing
- Medication Adherence Partner, Electronic pill bottle
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pennsylvania
Opioid Overdose
A Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres Powder
A Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres Nasal Powder.
- Trial name
- NCT04713709
- Testing
- Nasus Pharma FMXIN001, Nasal Naloxone liquid spray
- Where
- Canada
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Nasus Pharma
HIV Infections
Reduction of Drug Use and HIV Risk Among Out-of-Treatment Methamphetamine Users
There is a need to identify and test effective strategies to reduce meth use and human immunodeficiency virus (HIV) risk behaviors in heterosexuals.
- Trial name
- NCT01161485
- Testing
- HIV Testing and Counseling, Contingency Management, Strengths-based case management
- Where
- United States
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Bronchopulmonary Dysplasia, Vitamin D Overdose
25OH Vitamin D Overdoses and Risk of Bronchopulmonary Dysplasia or Death
Several studies have demonstrated that vitamin D deficiency at birth is a risk factor of bronchopulmonary dysplasia. However, in an animal model of bronchopulmonary dysplasia vitamin D overdose has also been associated with an…
- Trial name
- 25OHVDORBPDD (NCT05944055)
- Testing
- Is 25 OH vitamin D overdose a risk factor of bronchopulmonary dysplasia or death ?
- Where
- France
- Volunteers
- 173 people
- Sponsor
- Hospices Civils de Lyon
Overdose Risk, Opioid Use Disorder
Kentucky Women's Justice Community Overdose Innovation Network - Phase II
This project continues our work with women in the Kentucky Women's Justice Community Overdose Innovation Network Phase II (WJCOIN-II) with the overall aim of reducing overdose risk during the transition from jail to rural…
- Conditions
- Overdose Risk, Opioid Use Disorder, Stimulant Use Disorders
- Trial name
- WJCOIN-II (NCT07179614)
- Testing
- Overdose Prevention Intervention Package (OPIP)
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Michele Staton
User-Computer Interface, Clinical Skills
Establishing Learning Curves in Virtual Simulation Training of Mastoidectomy
The purpose of this study is to establish learning curves of mastoidectomy training in virtual surgical simulation training, to establish the long-term effect of repeat simulation training and to explore the transfer of skills…
- Conditions
- User-Computer Interface, Clinical Skills, Motor Skills, Temporal Bone
- Trial name
- NCT01966185
- Testing
- Tutor function on
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Psychiatric Disorder, Drug Use
Drug Use & Infections in ViEtnam: Mental Health Intervention for INjecting Drug Users
The main objective of this study is to show that People Who Inject Drugs (PWID) suffering initially from a major depressive disorder, a psychotic disorder and/or had a suicide risk and who received a community-based psychiatric…
- Trial name
- DRIVEMINDII (NCT05886504)
- Testing
- Community-based psychiatric intervention
- Where
- Vietnam
- Volunteers
- 567 people
- Sponsor
- ANRS, Emerging Infectious Diseases
HIV Infections, Heroin Dependence
Directly Administered Antiretroviral Therapy (DAART) Among HIV-1infected Injecting Drug Users (IDUs) in Chennai, India
Though the HIV epidemic in India is predominantly among heterosexual populations, it is estimated that there are approximately 1.1 million injection drug users (IDUs) in India with HIV prevalence as high as 64% among IDUs in…
- Trial name
- DAART+ (NCT00709007)
- Testing
- Directly Administered Antiretroviral Therapy (DAART), SAT
- Where
- India
- Sponsor
- Johns Hopkins University
HIV Infection
Use of Incentives to Engage Drug Users in HIV Therapy
Highly active antiretroviral therapy (HAART), the current standard of care for treatment of HIV infection, is highly effective when taken appropriately.
- Trial name
- Incentives-1 (NCT01526421)
- Testing
- monetary reinforcer
- Where
- Canada
- Volunteers
- 301 people
- Sponsor
- University of British Columbia
Methamphetamine Dependence, Methamphetamine Withdrawal
Characterizing Methamphetamine Withdrawal in Recently Abstinent Methamphetamine Users: A Pilot Study
Methamphetamine use has escalated in recent years. Methamphetamine use has also spread throughout the country. Although much information has been gathered on the treatment of cocaine abuse, very little information has been…
- Trial name
- NCT00653263
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Arkansas
Marijuana Dependence
Effect of Oxytocin on Stress in Marijuana Users
The purpose of this study is to evaluate how people who frequently use marijuana respond to a stressful task, and if a medication (oxytocin) affects this response.
- Trial name
- NCT01335789
- Testing
- Oxytocin, Saline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medical University of South Carolina
Co-Occurring Alcohol and Drug Misuse
Contingency Management for the Treatment of Co-Occurring Alcohol and Drug Misuse
Contingency management (CM) is a type of treatment used in the substance abuse field. Patients' behaviors are rewarded for adherence to a treatment plan.
- Trial name
- NCT02222389
- Testing
- CM for Alcohol, CM for drugs, CM for both substances
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Washington State University
Psychological
Service-user Experiences of Text-based Conversations With a Computer About Their Difficulties
Mental health problems such as anxiety and depression are common. Services are finding it difficult to treat people quickly. This has led to computers being used to treat common problems.
- Trial name
- NCT03524196
- Testing
- Manage Your Life Online (MYLO)
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- University of Manchester
Behavior
RxConnect User Testing Study
Background Medication errors are the leading cause of preventable harm in healthcare settings worldwide. An estimated 237 million medication errors occur in England alone every year, with 66 million considered clinically…
- Trial name
- NCT05493072
- Testing
- RxConnect
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Intravenous Drug Usage
Correlates and Consequences of Increased Immune Activation in Injection Drug Users
The goal of this study is to learn how injection drug use may affect the immune system.
- Trial name
- NCT01831284
- Testing
- Sigmoidoscopy with biopsy
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
HIV, Hepatitis
A Network & Dyad HIV Prevention Intervention for IDU's - 1
The purpose of this study is to evaluate a peer-based HIV prevention intervention that targets active injection drug users and their drug and sex partners.
- Trial name
- NCT00218335
- Testing
- Intervention Condition, Control Condition
- Where
- United States
- Volunteers
- 1,024 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV, Substance Use
Adherence Intervention for HIV-infected Drug Users
Many people living with HIV use illicit drugs, which leads to worsened health outcomes and increased transmission of HIV due to poor adherence to medication regimens.
- Trial name
- NCT02907697
- Testing
- Life Steps-Drug Use, General Health Education
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of Texas at Austin