Clinical trials: Drugs of Abuse
Substance Abuse
Impact of Personalized Feedback Alone on Substance Use Behaviors
The investigators seek to develop a more efficient and effective approach to providing brief behavioral health interventions for risky substance use behaviors by comparing a brief coach directed intervention to a tailored report…
- Trial name
- NCT01501318
- Testing
- Personalized feedback report, Personalized feedback report plus education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Missouri-Columbia
Anxiety, Prescription Drug Abuse and Dependency
Prescription of Benzodiazepines by General Practitioners: Characteristics of Prescribing Trend and Implementation of an Online Educational Program
Portugal has the highest benzodiazepine utilization compared to other European countries. The high utilization of benzodiazepines has been a concern due to reported side effects of long-term use and dependence.
- Trial name
- NCT04925596
- Testing
- ePrimaPrescribe online educational program, ComunicaSaudeMental online educational program
- Where
- Portugal
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Intravenous Drug Abuse, HIV Infections
Reducing Health Problems Associated With Injection Drug Use
The purpose of this study is to develop and test an intervention to reduce bacterial and viral infections among injection drug users.
- Trial name
- NCT01128920
- Testing
- Skin and Needle Hygiene Intervention, No intervention - assessment-only condition
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent)
An Opioid Prescribing Nudge
Analyze baseline concurrent opioid prescribing metrics at the individual prescriber level in the Duke Health System on the identified three main outcome measures.
- Conditions
- Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent), Prescription Drug Abuse and Dependency, Health Behavior
- Trial name
- OHS (NCT04069403)
- Testing
- Automated Reports on prescription patterns for their patients
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Duke University
Drug Usage, Drug Abuse
Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use
The objective of this study is to test whether screening and brief intervention for drug use among primary care patients leads to improved drug-related outcomes (such as decreased drug use and consequences).
- Conditions
- Drug Usage, Drug Abuse, Drug Dependence
- Trial name
- ASPIRE (NCT00876941)
- Testing
- Standard Brief Intervention, Enhanced Brief Intervention, Control: Information and Feedback
- Where
- United States
- Volunteers
- 589 people
- Sponsor
- Boston Medical Center
Drug Abuse
Project Health Link: Connecting Patients With Services
The proposed study will compare three alternative interventions in the emergency department (ED) to promote linkage to substance abuse assessment, referral and treatment entry for those who meet abuse/dependence criteria for…
- Trial name
- NCT00251173
- Testing
- Strengths Based Case Management (SBCM), Motivational Enhancement Therapy (MET), Brief Informational Feedback (BIF) session
- Where
- United States
- Volunteers
- 755 people
- Sponsor
- University of Michigan
Baseline Epidemiologic Assessment
Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)
The main objectives of this study are to provide surveillance/descriptive data to (a) assess utilization of MorphaBond ER and selected comparators overall and by age group and census regions using nationally-projected quarterly…
- Trial name
- BEAD-MB (NCT04033094)
- Testing
- MorphaBond ER, Comparator Drug
- Where
- United States
- Volunteers
- 17,566 people
- Sponsor
- Daiichi Sankyo
Cocaine Dependence
Oxytocin in Cocaine Dependence
Stress is likely involved in relapse to cocaine use. This project will investigate the role oxytocin may play in the stress response in cocaine-dependent men and women and examine how oxytocin may impact brain activity in…
- Trial name
- NCT01573273
- Testing
- Oxytocin, Saline
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Medical University of South Carolina
Overdose, Opioid-related Disorders
Phone Interview to Prevent Recurring Opioid Overdoses
There has been a dramatic rise in opioid overdose (OOD) deaths in recent years. Attempts to ameliorate the problem have largely focused on increasing the accessibility of naloxone, an opioid antagonist that is effective in OOD…
- Conditions
- Overdose, Opioid-related Disorders, Drug Addiction, Drug Abuse
- Trial name
- TTIP-PRO (NCT02282306)
- Testing
- TTIP-PRO
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Medication Abuse
Obstacles to Deprescribing Among French Patients Over 75 Years of Age Treated in the Geriatric Hospital Network
The aim of this study is to highlight action guidelines to encourage acceptance of deprescribing in people over 75 years of age: training, therapeutic education, post-prescription follow-up, specific patient pathways, specific…
- Trial name
- OUTMEDIC-FR (NCT05327634)
- Testing
- self-questionnaire
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Hôpital NOVO
Alcohol Abuse, Substance Use
Adaptation and Evaluation of Bright Horizons
This study will test if a program called 'Bright Horizons' is effective at reducing binge substance use among adolescents. Bright Horizons is a culturally adapted intervention developed and tested through a partnership between…
- Trial name
- NCT05743699
- Testing
- Bright Horizons, Case Management
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Substance Abuse, Stress, Psychological
Drug Abuse During the COVID-19 Pandemic.
The pandemic we live through has put various sectors of the medical system and its tributaries to the test. The accumulation of external and internal stress has been completely correlated with the predisposition to…
- Trial name
- NCT04811352
- Where
- Mexico
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Hepatitis C, PrEP
HepC Micro-elimination on MSM and TGW Population.
This is an observational study, in which a single visit will be carried out, which includes a questionnaire on sexual habits and in which the possibility of carrying out a screening for Hepatitis C will be offered.
- Conditions
- Hepatitis C, PrEP, Drugs of Abuse
- Trial name
- NCT06847958
- Where
- Spain
- Volunteers
- 13,161 people, healthy volunteers welcome
- Sponsor
- Projecte dels NOMS Hispanosida
Drug Abuse
Behavioral and Subjective Efficacy of Ramelteon in Subjects With a History of Polydrug Abuse
The purpose of this study is to determine the relative abuse potential of ramelteon, once daily (QD), compared to triazolam in subjects with a history of drug abuse.
- Trial name
- NCT00671632
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Takeda
Opioid-Related Disorders, Drug Addiction
Medication Treatment for Opioid Use Disorder in Expectant Mothers
The primary objective of this study is to evaluate the impact of treating opioid use disorder (OUD) in pregnant women with extended-release buprenorphine (BUP-XR), compared to sublingual buprenorphine (BUP-SL), on mother and…
- Conditions
- Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse
- Trial name
- MOMs (NCT03918850)
- Testing
- Buprenorphine Injection, Buprenorphine Sublingual Product
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- T. John Winhusen, PhD
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Addiction, Substance Abuse Drug Chronic
Stage III Community-based Efficacy Trial for Mothering From the Inside Out
This is a Stage III community-based randomized clinical efficacy trial testing Mothering from the Inside Out (MIO), the first evidence-based parenting intervention designed to be delivered by addiction counselors in addiction…
- Conditions
- Addiction, Substance Abuse Drug Chronic, Child Neglect, Child Neglect Emotional
- Trial name
- NCT02955199
- Testing
- Mothering From the Inside Out (MIO), Parent Education
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Yale University
Intimate Partner Violence Against Women, Alcohol Abuse
Motivational Strategies in Batterer Intervention Programs for Offenders With Alcohol/Drug Abuse Problems (IMP-ADAPs)
Alcohol and/or drug abuse problems (ADAPs) have been consistently identified in the scientific literature as a risk factor of intimate partner violence against women (IPVAW).
- Conditions
- Intimate Partner Violence Against Women, Alcohol Abuse, Drug Abuse
- Trial name
- IMP-ADAPs (NCT03885349)
- Testing
- SBIP+ ADAPs-IMP, SBIP+IMP
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Valencia
Substance Abuse, Offenders
Effects of Manualized Treatment in a Seamless System
The specific aims of this project are: 1. To conduct a randomized block experiment to test the effectiveness of different models of the seamless supervision/treatment system and traditional criminal justice supervision on…
- Conditions
- Substance Abuse, Offenders, Criminal Thinking, HIV Risk Behaviors
- Trial name
- Man Tx (NCT01372033)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 251 people
- Sponsor
- George Mason University
Marijuana Abuse
Evaluating Responses to Drug-Related Cues Versus Neutral Cues to Understand the Effects of Marijuana Craving - 1
The majority of past research on marijuana treatment has specifically targeted the alleviation of withdrawal symptoms. Minimal focus has been placed on how altering craving effects may play a role in treating marijuana addiction.
- Trial name
- NCT00218478
- Testing
- Cue Desensitization
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wayne State University