Clinical trials: Drugs of Abuse
Marijuana Abuse
Evaluating Responses to Drug-Related Cues Versus Neutral Cues to Understand the Effects of Marijuana Craving - 1
The majority of past research on marijuana treatment has specifically targeted the alleviation of withdrawal symptoms. Minimal focus has been placed on how altering craving effects may play a role in treating marijuana addiction.
- Trial name
- NCT00218478
- Testing
- Cue Desensitization
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Methamphetamine, Amphetamine Dependence
Study of Medical Treatment for Methamphetamine Addiction
Currently there are no medications approved for the treatment of methamphetamine addiction. Bupropion is an antidepressant that is approved by the Food and Drug Administration (FDA) for the treatment of depression and for…
- Conditions
- Methamphetamine, Amphetamine Dependence, Pharmacogenetics, Methamphetamine Dependence
- Trial name
- BUP PGx (NCT00833443)
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of California, Los Angeles
Body Dysmorphic Disorder, Steroid Abuse
CBT for Muscle Dysmorphia and Steroid Abuse: A Randomized Controlled Trial
The goal of this clinical trial is to evaluate the effectiveness of cognitive behavioral therapy (CBT) in treating muscle dysmorphia (MD) under body dysmorphic disorder (BDD) and steroid/performance-enhancing drug (PED) abuse in…
- Conditions
- Body Dysmorphic Disorder, Steroid Abuse, Body Dysmorphic Disorder (BDD), Subtype: Muscle Dysmorphia
- Trial name
- NCT06781853
- Testing
- Cognitive Behavioral Therapy (CBT)
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Uskudar University
Cannabis, Alcohol Effect
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
- Conditions
- Cannabis, Alcohol Effect, Driving Under the Influence of Alcohol and Other Drugs
- Trial name
- THC-ETOH-I (NCT02709954)
- Testing
- Active inhaled delta-9-THC, Active Oral Ethanol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Drug Abuse
Indirect Assessment and Intervention for Perinatal Drug Use
The purpose of this study is to assess the validity of an indirect computer-delivered screener for drug use and assess the efficacy of a computer-delivered brief intervention with urban post-partum women at-risk for substance…
- Trial name
- NCT01650675
- Testing
- WIDUS computer-delivered, indirect brief intervention
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Wayne State University
Substance-related Disorders, Drug Addiction
Buprenorphine and Integrated HIV Care
The purpose of this study is to examine the efficacy of providing two levels of psychosocial support along with buprenorphine/naloxone (BUP) maintenance to opioid dependent patients receiving their care in an HIV clinical care…
- Conditions
- Substance-related Disorders, Drug Addiction, Human Immunodeficiency Virus, AIDS
- Trial name
- NCT00317460
- Testing
- Physician Management, Counseling
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Yale University
Drug Use, Drug Abuse
Prevention of Post Sexual Assault Stress
The purpose of this study is to evaluate whether a brief intervention in video format, that includes education about reactions to assault and modeling of adaptive coping strategies, designed to reduce post assault drug use or…
- Conditions
- Drug Use, Drug Abuse, Posttraumatic Stress Disorder
- Trial name
- NCT01430624
- Testing
- PPRS, PIRI
- Where
- 2 sites in United States
- Volunteers
- 245 people
- Sponsor
- Medical University of South Carolina
Intimate Partner Violence Against Women, Alcohol Abuse
Motivational Strategies in Batterer Intervention Programs for Offenders With Alcohol/Drug Abuse Problems (IMP-ADAPs)
Alcohol and/or drug abuse problems (ADAPs) have been consistently identified in the scientific literature as a risk factor of intimate partner violence against women (IPVAW).
- Conditions
- Intimate Partner Violence Against Women, Alcohol Abuse, Drug Abuse
- Trial name
- IMP-ADAPs (NCT03885349)
- Testing
- SBIP+ ADAPs-IMP, SBIP+IMP
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Valencia
Delinquency, HIV Risk
The ProGirls Study
Girls in the juvenile justice system who have high rates of delinquency, drug abuse, and trauma are particularly at risk for engaging in risky sexual behavior and for contracting HIV/AIDS or other sexually transmitted infections…
- Conditions
- Delinquency, HIV Risk, Substance Use, Trauma Exposure
- Trial name
- NCT02112201
- Testing
- Integrated intervention for parents and adolescent girls
- Where
- United States
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Substance Abuse
Impact of Personalized Feedback Alone on Substance Use Behaviors
The investigators seek to develop a more efficient and effective approach to providing brief behavioral health interventions for risky substance use behaviors by comparing a brief coach directed intervention to a tailored report…
- Trial name
- NCT01501318
- Testing
- Personalized feedback report, Personalized feedback report plus education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Missouri-Columbia
Drug Use Disorders, Illicit Drug Use
An Initial Study of the Implementation of Digital Therapeutics for Substance Use Disorders in Primary Care
The DIGITS Trial addresses a critical knowledge gap: How to best implement digital treatments for opioids and other substance use disorders in primary care.
- Conditions
- Drug Use Disorders, Illicit Drug Use, Alcohol-Related Disorders
- Trial name
- DIGITS Pilot (NCT04907045)
- Testing
- Health Coaching, Practice Facilitation, Standard Implementation
- Where
- United States
- Volunteers
- 1,552 people
- Sponsor
- Kaiser Permanente
Depression, Alcoholism
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
The purpose of this study is to learn the environmental and psychological factors that impact suicidality in patients diagnosed with Bipolar Disorder.
- Conditions
- Depression, Alcoholism, Drug Abuse
- Trial name
- NCT02604277
- Testing
- Interpersonal and Social Rhythm Therapy (ISRT), Bipolar-Specific Cognitive Behavioral Therapy (CBT), Mindfulness-Based Stress Reduction (MBSR)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Emory University
Drug Addiction, HIV
The Cedar Project: Impact of mHealth for HIV Prevention Among Young Indigenous People Who Use Illicit Drugs
This study will examine the effect of a culturally-safe two-way supportive text message intervention to reduce HIV vulnerability among young Indigenous people who use illicit drugs in a community-based setting.
- Trial name
- NCT02437123
- Testing
- The Cedar Project mHealth intervention
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- University of British Columbia
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Intensive Care Unit Syndrome, Drug Abuse
Addiction in Intensive Cardiac Care Units
Background: Illicit drug use is a growing issue in Europe and leading cause of acute cardiac events in patients admitted to intensive cardiac care units.
- Conditions
- Intensive Care Unit Syndrome, Drug Abuse, Substance-Related Disorders, Cardiovascular Events
- Trial name
- ADDICT-CCU (NCT05063097)
- Testing
- urine test, Fagerström questionnaire, Exhaled carbon monoxide (CO) measurement
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Drugs of Abuse
An Evaluation of California's Experiment With HOPE
The phase I evaluation is intended to assess whether or not frequent drug testing and immediate short-term incarceration for drug use and/or other violations and mandated drug treatment for multiple violations, reduces the…
- Trial name
- NCT01237691
- Testing
- HOPE supervision, Parole-as-usual
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Pepperdine University
Suicidal Ideation, Social Behavior
Massive Mental Health Screening Using Smartphones in 24 Pre-graduate Education Centers in Mexico City: TEDUCA Survey Protocol
The objective of this study is to make a massive suicide risk and social behavior assessment in 24 pre-graduate education centers in Mexico City (approximately 30,000 students aged between 15 and 22 years), taking also into…
- Conditions
- Suicidal Ideation, Social Behavior, Depression, Depressive Disorder
- Trial name
- TEDUCA (NCT04067076)
- Testing
- Self-administered evaluation questionnaire
- Where
- Mexico
- Volunteers
- 30,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Bcenzodiazepines, Abuse, Retrospective Study, Focus Groups, Real-world Study
A Study of the Effectiveness of Electronic Interventions on the Standardized Prescription Benzodiazepines and Z-drugs
A retrospective surveys and group interviews focusing on the prescription and abuse of benzodiazepines will be carried out in China.
- Trial name
- NCT03724669
- Testing
- waiting list, benzodiazepines related knowledge intervention
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Shanghai Mental Health Center
Drug Usage, Drug Abuse
Assessing Screening Plus Brief Intervention's Resulting Efficacy (ASPIRE) to Stop Drug Use
The objective of this study is to test whether screening and brief intervention for drug use among primary care patients leads to improved drug-related outcomes (such as decreased drug use and consequences).
- Conditions
- Drug Usage, Drug Abuse, Drug Dependence
- Trial name
- ASPIRE (NCT00876941)
- Testing
- Standard Brief Intervention, Enhanced Brief Intervention, Control: Information and Feedback
- Where
- United States
- Volunteers
- 589 people
- Sponsor
- Boston Medical Center
Drug Abuse, Schizophrenia
Contingency Management of Psychostimulant Abuse in the Severely Mentally Ill
The purpose of this study is to determine the effectiveness of a behavioral treatment, contingency management, in reducing stimulant use in persons with serious mental illness.
- Conditions
- Drug Abuse, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT00809770
- Testing
- Contingency Management, Non Contingent Control Condition
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- University of Washington