Clinical trials: Dry Eye, completed
Dry Eye
Hydroxypropyl-methylcellulose and GlicoPro® Eyedrops in the Treatment of Dry Eye Disease: Clinical Study
The goal of this clinical trial is to learn if Hydroxypropyl-methylcellulose and GlicoPro® eyedrops work to treat mild-to-moderate dry eye disease in adult patients.
- Trial name
- NCT06726525
- Testing
- HPMC+GlicoPro eyedrops, Hydroxypropyl-methylcellulose
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- University of Milan
Dry Eye Syndromes
Lubricating Effectiveness of Carragelose Eye Drops in Patients Affected by Mild to Moderate Dry Eye
Patients suffering from dry eye syndrom will treat their eyes with Carragelose® eye drops three times a day for 28 days. Before, in the middle and at the end of the treament period patients will be exposed to adverse conditions…
- Trial name
- NCT06262100
- Testing
- Carragelose
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Marinomed Biotech AG
Dry Eye
Acupoint Therapy Device for Dry Eye
To built a dry eye acupoint therapeutic instrument by stimulating acupoints with low impulse current .And the safety of the dry eye acupoint treatment device will be tested and the initial validation will be verified.
- Trial name
- NCT06720428
- Testing
- dry eye acupoint therapy instrument, Artificial tear
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Ocular Graft-versus-host Disease
Allogeneic Platelet Lysate Eye Drops for the Treatment of Severe Chronic Ocular Graft-versus-host Disease
The study evaluates the efficacy and safety of allogeneic platelet lysate eye drops in patients with severe ocular graft versus host disease refractory to conventional systemic and local treatments.
- Trial name
- NCT05311514
- Testing
- Allogeneic platelet lysate eye drops
- Where
- Russia
- Volunteers
- 38 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Dry Eye Syndromes
Efficacy of a New Nanoemulsion Artificial Tear Targeting Dry Eye Disease
This is a prospective cohort study to compare subjective changes in symptoms using the Ocular Surface Disease Index (OSDI) questionnaire, following the recommended dosage of the new nanoemulsion eye drops (Systane Complete)in…
- Trial name
- NCT06188260
- Testing
- Systane COMPLETE Lubricant Eye Drops
- Where
- Hong Kong
- Volunteers
- 31 people
- Sponsor
- The Hong Kong Polytechnic University
Dry Eye Syndromes
ACCURATE Study for Subjects With Dry Eyes
To determine treatment and imaging outcomes in bilateral ocular surface disease management with an intracanalicular dexamethasone (0.4 mg) insert compared to standard topical over-the-counter artificial tears lubrication…
- Trial name
- ACCURATE (NCT04237012)
- Testing
- Dextenza 0.4Mg Intracanalicular Insert, Over the counter Artificial tears
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Eye Centers of Racine and Kenosha
Dry Eye
Effect of Povidone-iodine 5% Vs 1% on the Ocular Surface in Intravitreal Injections of Anti-VEGF
Objective and subjective comparison between the use of povidone-iodine 1% vs 5% as antiseptic in patients that need anti-VEGF intravitreal injection
- Trial name
- anti-VEGF (NCT06710951)
- Testing
- Change of normal concentration of povidone-iodine 5% to 1%
- Where
- Mexico
- Volunteers
- 88 people
- Sponsor
- José Gerardo García Aguirre
Dry Eye Disease
Study of SY-201 Ophthalmic Solution in Subjects With Dry Eye Disease
This is a phase 2, multi-center, double-masked, randomized, vehicle-controlled, dose-response, parallel-group study designed to evaluate the safety and tolerability and ocular efficacy of SY-201 Ophthalmic Solution versus vehicle…
- Trial name
- NCT05370495
- Testing
- SY-201 Ophthalmic Solution 2.0%, SY-201 Ophthalmic Solution 1.0%, SY-201 Ophthalmic Solution 0.5%
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Seinda Pharmaceutical Guangzhou Corporation
Dry Eye Syndromes, Dry Eye
Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland Disfunction
A Randomized, Masked (Evaluator), Controlled, Prospective Pilot Study of the Effectiveness and Safety of the Tixel®, Versus LipiFlow® in the Treatment of Meibomian Gland Dysfunction.
- Conditions
- Dry Eye Syndromes, Dry Eye, Meibomian Gland Dysfunction
- Trial name
- NCT04889950
- Testing
- Tixel C, LipiFlow
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Novoxel Ltd.
Sjogren's Syndrome, Dry Eye
Nasal Spray Study in Sjogren's Dry Eye Disease
This study will investigate how well OC-01 (varenicline) nasal spray can treat the signs and symptoms of dry eye disease in those Sjogren's Syndrome.
- Trial name
- NCT05700422
- Testing
- Varenicline Nasal Spray
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Pennsylvania
Dry Eye, Dry Eye Syndromes
Intra-Nasal Mechanical Stimulation (INMEST) As a Treatment Method for the Relief of Symptoms of Dry Eye
The purpose of the study is to investigate the degree of symptom relief in people with signs or symptoms of dry eyes after self-treatment at home with the Walther System delivering INMEST (intranasal mechanical stimulation).
- Trial name
- NCT05887336
- Testing
- Walther System, Non preserved ocular lubricants, Eye lid procedure
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 106 people
- Sponsor
- Abilion Medical Systems AB
Dry Eye Disease, Xerostomia
Sphenopalatine Ganglion Stimulation for Ocular and Oral Dryness
Dry Eye Disease (DED) is a multifactorial pathology characterized by inflammation of the lacrimal functional unit that develops in ocular surface pathology, severely affecting patients quality of life.
- Trial name
- NCT05187533
- Testing
- Osteopathic protocol of Sphenopalatine Ganglion Stimulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Dry Eye Disease (DED)
Perfluorohexylcotane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Gobi Study)
This trial will evaluate the efficacy, safety, and tolerability of NOV03 ophthalmic solution in comparison to a saline control for the treatment of the signs and symptoms of Dry Eye Disease (DED) associated with Meibomian Gland…
- Trial name
- NCT04139798
- Testing
- NOV03
- Where
- 29 sites in United States
- Volunteers
- 599 people
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye, Dry Eye Syndromes
A Phase 3, Multi-Center Study Evaluating PL9643 in Patients with Dry Eye
This is a multi-center, double-masked, randomized, vehicle-controlled study testing PL9643, an ophthalmic solution to determine if safe and efficacious for dry eye patients.
- Trial name
- MELODY-1 (NCT05201170)
- Testing
- Vehicle Ophthalmic Solution, PL9643 Ophthalmic Solution
- Where
- 18 sites in United States
- Volunteers
- 575 people
- Sponsor
- Palatin Technologies, Inc
Dry Eye Syndrome
Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dry Eye
The objective of this study is to evaluate tolerability, safety and efficacy of Lubricin 150 µg/ml eye drops when compared to a widely used commercial 0.18% sodium hyaluronate eye drop formulation in moderate dry eye patients.
- Trial name
- NCT02507934
- Testing
- Lubricin, Sodium Hyaluronate
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Dompé Farmaceutici S.p.A
Dry Eye Syndrome
A Study to Assess Symptom Relief and Product Tolerability of ABBV-444 Drops in Adult Participants
Dry Eye Disease (DED) is a condition where the tear film of the eye becomes unstable and along with ocular surface inflammation and damage leads to inadequate tear production and eye lubrication.
- Trial name
- NCT05878067
- Testing
- ABBV-444
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AbbVie
Dry Eye Disease
Evaluation of Ocular Comfort With ISTA Tears vs Systane
To assess the comfort preference of ISTA Tears vs Systane in patients with dry eye disease (DED)
- Trial name
- NCT01650584
- Testing
- ISTA Tears, Systane
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye, Contact Lens Complication
Dailies Total 1 Sphere Contact Lenses
CL discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society in their seminal report on contact lens (CL) discomfort as a condition that results in "episodic or persistent adverse ocular…
- Trial name
- NCT05239494
- Testing
- DT1 Sphere Contact Lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dry Eye Disease
HU007 in Patients with Dry Eye Syndrome
A multicenter, Randomized, Double blind, Restasis®-controlled Non-inferiority, Moisview® Eye Drops Controlled Superiority, Phase III Study to Evaluate the Efficacy and Safety of HU007 Eye Drops in Patients with Dry Eye Syndrome
- Trial name
- NCT05743764
- Testing
- HU007, Restasis, Moisview Eye drop
- Where
- South Korea
- Volunteers
- 328 people
- Sponsor
- Huons Co., Ltd.
Dry Eye Disease (DED)
Cross-linked CMC and Silk Proteins in Eye Disease
Data analyses and revision of the DED symptoms. A novel ophthalmic solution containing cross-linked CMC (CX-CMC) and Silk Proteins (SP) has been made available on the market.
- Trial name
- NCT06605365
- Testing
- CX-HA and CS
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- D&V FARMA srl