Clinical trials: Dry Eye, completed
Dry Eye Disease, Meibomian Gland Dysfunction
Safety of Tinted Soft Scleral Eye Shields When IPL is Applied on Eyelids
The purpose of this study is to verify the safety of tinted soft scleral eye shields when IPL is applied directly on eyelids.
- Trial name
- NCT05168670
- Testing
- Protection of eyes with tinted soft scleral eye shields
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Lumenis Be Ltd.
Systemic Lupus, Sjogren's Syndrome
Evaluation of Influenza A/H3N2 Vaccine in Patients With Rheumatologic Diseases
Studies in the literature have shown reduced effectiveness of influenza A (H3N2) virus vaccine (20-40%) when compared to A (H1N1) and influenza B.
- Trial name
- NCT03540823
- Testing
- Inactivated and fragmented influenza vaccine (A / Michigan / 45/2015 (H1N1) pdm09-like virus, A / Singapore / INFIMH-16-0019 / 2016 (H3N2) -like virus; B / Phuket / 3073/2013-like virus)
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Dry Eye
Effect of an Oral Supplement Containing Omega-3 and Omega-6 on Dry Eye Symptoms
This study will investigate the effectiveness of two oral supplements on the ocular signs and symptoms in symptomatic dry eye patients.
- Trial name
- TURMERIC (NCT03265327)
- Testing
- Oral supplement containing omega-3 and omega-6, Oral supplement containing coconut and olive oil
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Nature's Way Canada
Meibomian Gland Dysfunction, Evaporative Dry Eye
Tear Film Innovations iLux Safety Study
The objective of this study was to measure the temperature of the cornea and surrounding eye tissue temperature immediately after heating the eyelids with the iLux device using the protocol treatment profile.
- Trial name
- NCT03055897
- Testing
- iLux 2020 System
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tear Film Innovations, Inc.
Dry Eye Syndromes
Effect of Cequa Treatment on Accuracy of Pre-operative Biometry & Higher Order Aberrations in Dry Eye Patients Undergoing Cataract Surgery
The purpose of this study is to examine the effect of Cequa treatment on the accuracy of pre-operative biometry and on corneal higher-order aberrations (HOAs) in cataract patients who have signs of dry eye disease.
- Trial name
- NCT04342988
- Testing
- Cequa
- Where
- 3 sites in United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Dry Eye Syndromes
Investigation of Preservative-Free Ophthalmic Solution in Ocular Dryness
This is a multicenter, prospective, observational, open-label, non-interventional study evaluating the clinical performance and the safety of 4 daily instillations of the ophthalmic solution in the treatment of eye discomfort, in…
- Trial name
- NCT05778942
- Testing
- Eyestil SYNFO
- Where
- 4 sites in Spain
- Volunteers
- 35 people
- Sponsor
- SIFI SpA
Non-exudative (Dry) Age-related Macular Degeneration (AMD)
HELP Therapy for Dry AMD
This is an open-label, single center clinical investigation to evaluate the efficacy and safety of Heparin-induced Extracorporeal Lipoprotein Precipitation (H.E.L.P.) Therapy as a treatment for non-exudative (dry) Age-related…
- Trial name
- HELPuc (NCT01840683)
- Testing
- H.E.L.P. therapy (H.E.L.P. Plasmat Futura System)
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- B.Braun Avitum AG
Dry Eye Syndromes
Validation of TearLab Osmometer - Human Factor Usability Report
The objective of this study is to validate the performance of the OcuSense TearLab™ osmolarity test when performed in physician office laboratories (POL) by health care professionals using human tear fluid collected from…
- Trial name
- NCT00731484
- Where
- 3 sites in United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- TearLab Corporation
Dry Eye Disease
Study of INS365 Ophthalmic Solution in Subjects With Dry Eye Disease
The purpose of this trial is to compare the effectiveness and safety of INS365 Ophthalmic Solution with Placebo when applied topically in subjects with dry eye disease.
- Trial name
- NCT00403715
- Testing
- diquafosol tetrasodium (INS365) Ophthalmic Solution
- Volunteers
- 500 people
- Sponsor
- Merck Sharp & Dohme LLC
Keratoconjunctivitis Sicca
A Dose-Escalation Study to Assess the Safety and Tolerability of LX214 Ophthalmic Solution in Healthy Volunteers, Followed by an Open-Label Evaluation of LX214 in Patients With Keratoconjunctivitis Sicca (KCS)
This is a first-in-man study for the purpose of determining the safety and tolerability of LX214 ophthalmic solution in healthy volunteers and in patients with dry eye syndrome.
- Trial name
- NCT00851734
- Testing
- voclosporin ophthalmic solution
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lux Biosciences, Inc.
Dry Eye Disease
Burden of Illness and Treatment Assessment of Patients With Dry Eye Disease: A Cross-Sectional Survey of Real-World Patients With Dry Eye Disease in the US
This study employed secondary database analysis of the Adelphi Dry Eye Disease (DED) Disease Specific Programme™ (DSP™), a templatized cross-sectional survey with retrospective data collection that is administered by Adelphi to a…
- Trial name
- NCT06018571
- Where
- United States
- Volunteers
- 946 people
- Sponsor
- Novartis Pharmaceuticals
Dry Eye Disease
Study Evaluating the Safety and Efficacy of AR-15512
This will be a Phase 3, multicenter, vehicle-controlled, double-masked, randomized study conducted at approximately 20 sites in the United States. All subjects enrolled will have dry eye disease (DED).
- Trial name
- COMET-2 (NCT05285644)
- Testing
- 0.003% AR-15512 ophthalmic solution, AR-15512 vehicle ophthalmic solution
- Where
- 23 sites in United States
- Volunteers
- 465 people
- Sponsor
- Aerie Pharmaceuticals
Dry Eye Syndrome
Oral Omega-3 Fatty Acids in the Treatment of Dry Eye Syndrome
The investigators hypothesize that oral omega-3-acid ethyl esters (Lovaza, GlaxoSmithKline, Research Triangle Park, NC) will decrease dry-eye related symptoms as well as clinical markers associated with dry eye disease…
- Trial name
- NCT01107964
- Testing
- Oral Omega-3-acid ethyl esters
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Milton S. Hershey Medical Center
Dry Eye
Civamide Nasal Solution for the Treatment of Dry Eye
Keratoconjunctivitis sicca (KCS) or Dry Eye Syndrome is a disease of the surface of the eye, tear film, and related ocular tissues.
- Trial name
- NCT02116244
- Testing
- Civamide Nasal Spray
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- Winston Laboratories
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Dry Eye Syndrome
In Vivo Measurement of Corneal Epithelial Changes in Dry Eye Patients
The purpose of this study is to measure corneal epithelial changes in dry eye subjects using a novel lubricant eye gel.
- Trial name
- NCT01483989
- Testing
- SYSTANE® Gel Drop lubricant eye gel
- Volunteers
- 19 people
- Sponsor
- Alcon Research
Primary Sjögren Syndrome
Neurotrophins Implications in Primary Sjögren Syndrome
Neurotrophins (NTs) constitute a family of growth factors, which regulated differentiation, proliferation, and survival of both neuronal cells and astrocytes.
- Trial name
- Neuro-SGSp (NCT01081184)
- Testing
- blood sample
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Sjogren's Syndrome
Fish Oil (Omega 3 ) in Sjogren's Syndrome
Sjögren's syndrome (pSS) is an autoimmune disorder affecting mainly the exocrine glands.this lead to dryness of the main mucosal surface ,such as the mouth ,eye,skin nose,pharynx,larynx and vagina .
- Trial name
- NCT05005806
- Testing
- Omega 3 fatty acid
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Hawler Medical University
Sjögren Syndrome, Pulmonary Hypertension
Early Detection of Pulmonary- and Pulmonary Vascular Disease in Sjögren Syndrome
According to the literature available pulmonary hypertension is present in 12 to 23% of patients suffering from Sjögren Syndrome. However epidemiological data are based on non-invasive measurements using echocardiography.
- Trial name
- NCT02752269
- Where
- Austria
- Volunteers
- 86 people
- Sponsor
- Medical University of Graz
Dry Eye Syndrome
Evaluation of Tear Osmolarity Over Time With Sustained Use of Thera Tears Lubricating Drops
The objective of the study is to demonstrate a change in osmolarity over time when moderate to severe dry eye subjects are treated with TheraTears lubricating drops.
- Trial name
- AKORN (NCT02758327)
- Testing
- TheraTears Lubricating Eye Drops
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Koffler Vision Group
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