Clinical trials: Dry Eye, completed
Dry Eye Syndrome
Efficacy and Safety of Rebamipide in Subjects With Dry Eye Syndrome
The purpose of this study is to evaluate the efficacy and safety of rebamipide ophthalmic suspension in subjects with dry eye syndrome.
- Trial name
- NCT01632137
- Testing
- Rebamipide 2% ophthalmic suspension
- Where
- 34 sites in United States
- Volunteers
- 564 people
- Sponsor
- Kubota Vision Inc.
Dry Eye Syndromes, Cataract
A Study of Sodium Carboxymethylcellulose for Post Cataract Surgery Dry Eye Symptoms
This study will evaluate the effect of sodium carboxymethylcellulose eye drops in the treatment of dry eye after cataract surgery.
- Trial name
- RLOTUS (NCT02028754)
- Testing
- Sodium Carboxymethylcellulose, Levofloxacin, Prednisolone
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Allergan
Dry Eye Syndromes
An Observational Study of OPTIVE PLUS® for the Treatment of Dry Eye Disease
This is an observational study of OPTIVE PLUS® in patients with dry eye disease in a routine clinical setting. Treatment decisions are made by the physician and reflect the physician's current standard of care.
- Trial name
- NCT01711424
- Testing
- OPTIVE PLUS®
- Where
- Germany
- Volunteers
- 1,209 people
- Sponsor
- Allergan
Dry Eye Syndromes
An Observational Study of Dry Eye Prior to Laser-Assisted in Situ Keratomileusis (LASIK) Therapy
This is an observational, study of dry eye in patients at the consultation visit prior to LASIK surgery. There is no treatment administered or intervention during the study.
- Trial name
- NCT01854905
- Testing
- No Treatment
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- Allergan
Dry Eye Syndrome
Safety and Efficacy of PG101 for Dry Eye Syndrome
To evaluate the safety and efficacy of 0.25% PG101 and 1.0% PG101 topical gel suspension compared to placebo when administered two times daily for 14 days in subjects diagnosed with dry eye syndrome
- Trial name
- PG101 (NCT02078661)
- Testing
- PG101
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Rhodes Pharmaceuticals, L.P.
Dry Eye Syndromes
Dose-response Study of OPC-12759 Ophthalmic Suspension
The purpose of this study is to evaluate the dose-response of OPC-12759 ophthalmic suspension in dry eye patients.
- Trial name
- NCT00234078
- Testing
- 0.5% OPC-12759, 1% OPC-12759, 2% OPC-12759
- Where
- Japan
- Volunteers
- 290 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Dry Eye Syndromes
Long Term Administration Study of OPC-12759 Ophthalmic Suspension
The purpose of this study is to evaluate safety and efficacy of OPC-12759 ophthalmic suspension during 52 weeks in dry eye patients
- Trial name
- NCT00818324
- Testing
- OPC-12759 Ophthalmic suspension
- Where
- 5 sites in Japan
- Volunteers
- 154 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Dry Eye
The Effect of Hinge Location on Corneal Sensation and Dry Eye After LASIK: A Systematic Review and Meta-analysis
The purpose of this study is to investigate the possible effect of hinge location on corneal sensation and dry eye syndrome after laser in situ keratomileusis (LASIK).
- Trial name
- NCT01507025
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yifan Feng
Myopia
A Prospective Study of Two Daily Disposable Contact Lenses
The purpose of this study was to evaluate the performance of a novel silicone hydrogel contact lens, DAILIES TOTAL1® (DT1) compared to the standard hydrogel material in 1-DAY ACUVUE® MOIST® (1DAVM) contact lens in contact lens…
- Trial name
- NCT01636986
- Testing
- Delefilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Dry Eye
The Effect of SYSTANE® BALANCE on Tear Film Break Up Time in Dry Eye Subjects
The purpose of this study was to evaluate the ability of SYSTANE® BALANCE dosed 4 times a day for 30 days to increase non-invasive tear film break up time over baseline, compared to a saline control, in dry eye subjects with…
- Trial name
- NCT01718028
- Testing
- Propylene glycol 0.6% ocular emulsion, Sodium chloride 0.9% saline solution
- Where
- Argentina
- Volunteers
- 51 people
- Sponsor
- Alcon Research
Moderate to Severe Dry Eye Syndrome
Efficacy of Nonsteroidal Anti-inflammatory Drugs in Treatment of Moderate and Severe Dry Eye Disease
This clinical trial is to investigate whether nonsteroid anti-inflammatory drops have therapeutic effect on moderate to severe dry eye patients.And compare the efficacy of the two nonsteroid anti-inflammatory drops with topical…
- Trial name
- NCT01562795
- Testing
- nonsteroid anti-inflammatory drops, corticosteroids, artificial tear substitute
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Wenzhou Medical University
Dry Eye Syndromes
Confirmatory Study of OPC-12759 Ophthalmic Suspension
The purpose of this study is to verify whether OPC-12759 ophthalmic suspension is effective compared with active control in dry eye patients.
- Trial name
- NCT00885079
- Testing
- OPC-12759 Ophthalmic suspension, Hyalein Mini Ophthalmic solution
- Where
- 5 sites in Japan
- Volunteers
- 188 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Dry Eye Syndrome
Investigation on Medical Management of Dry Eye Patients
Dry eye is a common complaint in patients encountered by ophthalmologists, which may result from the inflammatory response and can occur in the absence of systemic disease.
- Trial name
- NCT01942226
- Where
- 2 sites in Taiwan
- Volunteers
- 466 people
- Sponsor
- National Cheng Kung University
Dry Eye
A Study To Investigate The Effects Of A Low Humidity Environment And Visual Tasking On Tear Film Protein Composition
The purpose of the study is to collect valuable data on the role of controlled humidity, temperature, airflow, and visual tasking in altering the tear film protein composition.
- Trial name
- NCT02005874
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Inflamax Research Incorporated
Dry Eye Syndrome, Myopia
Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers
The purpose of this study was to evaluate the reduction of contact lens-related dryness symptoms when symptomatic weekly/monthly contact lens wearers were switched to DAILIES® AquaComfort Plus® lenses for a two-week period using…
- Trial name
- NCT01614600
- Testing
- Nelfilcon A contact lenses
- Volunteers
- 88 people
- Sponsor
- Alcon Research
Dry Eye Syndrome
Evaluation of the Effect of Repeated Usage on the Tear Film Characteristics of an Investigational Eye Drop in Dry Eye Sufferers
The main objectives of the investigation will be to assess the effect of the repeated usage of an investigational eye drop on the tear film characteristics of dry eye sufferers and demonstrate the benefit of this eye drops for…
- Trial name
- NCT01339936
- Testing
- Carboxymethylcellulose sodium, glycerin and polysorbate 80
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Optometric Technology Group Ltd
Dry Eye Syndrome
Correlation of Different Signs for Assessment of Dry Eye Syndrome
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response of the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01753687
- Testing
- Ocular scattering of the tear film, Optical Coherence Tomography (OCT), Measurement of tear film osmolarity
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Dry Eye Syndrome
Influence of Lachrymal Substitutes on Tear Film Thickness in Patients With Moderate Dry Eye Syndrome
Dry eye syndrome is a highly prevalent ocular disease with an increasing incidence in the elderly population. Topically administered lubricants are the basis for treatment of this disease.
- Trial name
- NCT01864330
- Testing
- Thealoz Duo®, Hyabak®, Hydrabak®
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Dry Eye Syndrome, Healthy
Effect of Olixia Pure® Eye Drops on Tear Film Thickness in Healthy Subjects
Dry eye syndrome (DES) is a common ocular disease, especially in the elderly population. Despite many treatment approaches, instillation of topical lubricants remains the mainstay of therapy.
- Trial name
- NCT01970917
- Testing
- Olixia pure eye drops
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dry Eye Syndromes
Performance and Acceptance of Optive Versus Hylocomod Eyedrops in Patients With Dry Eye Symptoms
This study evaluates the performance and acceptance of Optive versus Hylocomod eyedrops, when administered for one month to patients with mild to moderate dry eye symptoms, with and without contact lenses.
- Trial name
- NCT00761202
- Testing
- A sterile solution containing sodium carboxymethylcellulose and glycerin, preserved with PURITE®, Sodium hyaluronate
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Allergan