Clinical trials: Dry Eye, completed
Dry Eye
Acupuncture for Dry Eye
The purpose of this study is to assess whether acupuncture is more effective than artificial tear drop in the treatment of dry eye.
- Trial name
- NCT01105221
- Testing
- Acupuncture, Refresh Plus
- Where
- 3 sites in South Korea
- Volunteers
- 150 people
- Sponsor
- Korea Institute of Oriental Medicine
Dry Eye Disease
Efficacy and Safety of SHR8028 Eye Drops for the Treatment of Dry Eye Disease
The study is being conducted to assess the efficacy, safety and tolerability of SHR8028 eye drops in comparison to the vehicle for the treatment of dry eye disease.
- Trial name
- NCT05841043
- Testing
- SHR8028 eye drops, Vehicle eye drops.
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Primary Sjögren Syndrome
Eye Dryness Evaluation in Primary Sjögren's Syndrome
The objective of this observational study is to develop new tools to assess primary Sjögren's syndrome (pSS) symptoms and to measure the severity of eye involvement in these patients.
- Trial name
- PEPSS (NCT03614299)
- Testing
- Ecological symptom measurements using a webapp, Interferometry
- Where
- France
- Volunteers
- 45 people
- Sponsor
- University Hospital, Brest
Dry Eye
The Effect of a Novel Blueberry Supplement on Dry Eye Disease
The objective of this study is to evaluate the efficacy of a novel oral supplement (gummy bear) with blueberry powder on reducing dry eye signs and symptoms and assess its safety.
- Trial name
- PLUM (NCT05027087)
- Testing
- Blueberry gummy
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- SightSage Foods and Nutrition Inc.
Incidence and Severity of Dry Eye After Myopic LASIK
The Effect of Ablation Depth on Dry Eye After LASIK Treatment of Myopia
The study tried to find the relation between ablation depth and degree of dryness after LASIK treatment of myopic patients
- Trial name
- NCT03228784
- Testing
- LASIK
- Volunteers
- 53 people
- Sponsor
- Minia University
Sjogren's Syndrome
Aerobic Exercise in Primary Sjögren's Syndrome
The purpose of this sudy is to investigate the effects of a regular aerobic exercise on aerobic capacity, fatigue, depression, quality of life, perception of symptoms and disease activity in women with pSS.
- Trial name
- AEPSS (NCT02370225)
- Testing
- aerobic exercise
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Samira Tatiyama Miyamoto, PhD
Dry Eye Disease
A Study Assessing the Safety and Efficacy of DE-101 Ophthalmic Suspension in Dry Eye Patients
To investigate the safety and efficacy of DE-101 to improve the signs and symptoms in dry-eye disease.
- Trial name
- NCT01468168
- Testing
- DE-101 Ophthalmic Suspension, DE-101 Ophthalmic Suspension Vehicle
- Where
- 13 sites in United States
- Volunteers
- 183 people
- Sponsor
- Santen Inc.
Dry Eye Syndromes
A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye Relief
A study to evaluate the tolerability and acceptability of an investigational eye drop formulation in patients with Dry Eye Disease.
- Trial name
- NCT02455050
- Testing
- Carboxymethylcellulose Sodium Based Eye Drops, Systane® Gel Drops, Genteal® Lubricant Gel Drops
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Allergan
Keratoconjunctivitis Sicca
An Open-Label Extension of a Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis Sicca
This is a safety extension enrolling subjects participating in Study OTX-101-2016-001 (NCT02688556)
- Trial name
- NCT02845674
- Testing
- OTX-101 0.09%
- Volunteers
- 258 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Dry Eye
The Retention Rate Between Brand A and Brand B Punctal Plugs
The purpose of this study is to determine if Parasol punctal occluders (Brand A) have a higher rate of retention than Superflex punctal plugs (Brand B).
- Trial name
- NCT01947517
- Testing
- Parasol Punctal Occluder, Superflex Punctal Occluder
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Queen's University
Dry Eye Syndrome
Efficacy and Safety of PRO-148 Ophthalmic Solution Versus SYSTANE® in the Treatment of Patients With Dry Eye Syndrome
The purpose of this study is to evaluate the efficacy and safety of PRO-148 ophthalmic solution compared with SYSTANE ® ophthalmic solution for the treatment of signs and symptoms of mild-to-moderate dry eye syndrome.
- Trial name
- PRO-148 (NCT01541891)
- Testing
- PRO-148 Ophthalmic Solution, Active Comparator: SYSTANE ® Ophthalmic Solution
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Dry Eye
Evaluation of the Efficacy and Safety of DM05 Versus Optive™ on the Treatment of Moderate to Severe Ocular Dryness
This study is a multicentric, comparative, randomized, investigator-blinded, in parallel groups study to demonstrate the non-inferiority of DM05 in comparison with Optive™, in terms of cornea and conjunctiva staining (Oxford…
- Trial name
- NCT03517748
- Testing
- DM05 eye drops, Optive™ eye drops
- Volunteers
- 80 people
- Sponsor
- Horus Pharma
Dry Eye Disease (DED)
Efficacy of Pilocarpine As a Secretagogue Versus Artificial Tears for the Treatment of Dry Eye
Management approaches for dry eye disease (DED) typically start with low-risk, easily accessible, patient-applied therapies like artificial tears for early-stage disease.
- Trial name
- NCT06752278
- Testing
- Pilocarpine, artificial tears
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Al-Azhar University
Dry Eye Syndromes
A Two Comparator, Controlled Phase 3 Study in Patients With and Without Evaporative Dry Eye
Omega 3 (OM3) Tear is a new unit dose emulsion, containing flaxseed/castor oil, which is being developed by Allergan. It is desirable to understand the effect that this new emulsion has on tear film evaporation and tear lipid…
- Trial name
- NCT02871440
- Testing
- Omega 3, Optive Advanced, Optive
- Volunteers
- 40 people
- Sponsor
- The University of New South Wales
Dry Eye Syndrome
Efficacy Comparative Study Between Tears Again®, Opticol® and Optive®
Primary Purpose: To compare the efficacy in treating dry eye syndrome in contact lens wearers or computer users of Tears Again® versus Opticol® versus Optive® Secondary Purpose: Subjective evaluation of symptomatology Evaluation…
- Trial name
- NCT00893243
- Where
- Portugal
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Hospital de Sao Sebastiao
Dry Eye
Clinical Study to Evaluate the Efficacy of Ectoin® Containing Eye Spray for Treatment of Dry Eye Disease
Subjective and objective evaluation of the efficacy and tolerability of preservative-free "Ectoin® Eye Spray - Colloidal" and comparison of the efficacy and tolerability between "Ectoin® Eye Spray - Colloidal" and Tears Again® in…
- Trial name
- NCT03519815
- Testing
- Ectoin® Eye Spray - Colloidal, Liposomal eye spray Tears Again®
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- University of Applied Sciences and Arts Northwestern Switzerland
Autoimmunity, Dry Eye Syndrome
Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome
Ocular surface disease, especially dry eye and scleritis, commonly affects patients with autoimmune diseases. Ocular surface immune cells are increased in autoimmune disease; however the full subset of immune cells activated is…
- Trial name
- NCT02715323
- Testing
- Cross-sectional study
- Where
- Singapore
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Sjogren's Syndrome
Adelphi Primary Sjogren's Syndrome (pSS) Disease Specific Programme (DSP)
Sjogren's Syndrome is a chronic autoimmune disease characterized by sicca (dryness) symptoms of the mouth and eyes. This autoimmune disease is less commonly studied and there are no licensed treatments to treat the underlying…
- Trial name
- NCT03501420
- Testing
- Interview, PSC questionnaire, PRFs
- Where
- United Kingdom
- Volunteers
- 2,223 people
- Sponsor
- GlaxoSmithKline
Digital Eye Strain, Computer Vision Syndrome
Effect of Yellow Light AG Mobile Phone Screen on Dry Eye and Asthenopia.
This study aimed to evaluate the protective effects of yellow-light etching anti-glare (AG) screen on Digital Eye Strain (DES) induced by prolonged video display terminal (VDT) use under dim environment, Based on the proved…
- Conditions
- Digital Eye Strain, Computer Vision Syndrome, Dry Eye, Asthenopia
- Trial name
- NCT07340359
- Testing
- reading 2h on smartphone
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Dry Eye Syndrome
CXCL9, CXCL10, CXCL11, and CXCR3 in Dry Eye Syndrome
The aim of this study is to investigate the expression of CXCL9, CXCL10, CXCL11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome.
- Trial name
- NCT00991679
- Where
- South Korea
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Chonnam National University Hospital
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