Clinical trials: Dry Eye
Ocular Pain, Dry Eye
Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers
The purpose of this study is to determine whether SYL1001 is safe for the prevention and treatment of ocular pain and dry eye syndrome.
- Trial name
- NCT01438281
- Testing
- SYL1001
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sylentis, S.A.
Dry Eye Syndromes
Ocular Surface Microbiome
The purpose of this study is to collect samples from the surface of eyelids to try to grow and identify bacteria or fungus that might be present, and to try to understand why people have dry eye symptoms.
- Trial name
- NCT02298881
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Washington
Dry Eye Syndromes
Efficacy and Safety Study for Ecabet Ophthalmic Solution for Treating Dry Eye Syndrome
The purpose of this study is to determine whether ecabet ophthalmic solution is an effective treatment for dry eye syndrome
- Trial name
- NCT00370747
- Testing
- Ecabet
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Bausch & Lomb Incorporated
Meibomian Gland Dysfunction (MGD)
Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction
This research study evaluates a prescription eye drop called Vevye® (cyclosporine 0.1%) for adults who have meibomian gland dysfunction (MGD), a common eye condition that can cause dry, irritated, or burning eyes.
- Trial name
- NCT07224529
- Testing
- Vevye(Cyclosporine 0.1% Ophthalmic Solution)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Sjogren's Syndrome
The Functioning of Immune and Hormonal Systems in Patients With Sjogren's Syndrome and in Healthy Volunteers
This study aims to learn more about how the immune and hormonal systems function in patients with Sjogren's syndrome, a disease in which the immune system does not function properly.
- Trial name
- NCT00001953
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Dry Eye
An Evaluation of the Daytime Use of an Investigational Lubricant Eye Drop
The purpose of this study is to describe the subjective assessments of an investigational lubricant eye drop.
- Trial name
- NCT01139372
- Testing
- FID 115958D (Lubricant Eye Drop)
- Volunteers
- 96 people
- Sponsor
- Alcon Research
Dry Eye Syndrome, Ocular Surface Disease
Influencing Factors on Dry Eye Syndrome and Ocular Surface Disease
Dry eye syndrome and ocular surface disease are very important ophthalmologic diseases. It is known that various inducers are involved.
- Trial name
- NCT03364322
- Testing
- Observation
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Dry Eye, Ocular Surface Disease
Evaluation of Lacrifill
Dry Eye Disease is defined as "a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability with potential damage to the ocular surface.
- Conditions
- Dry Eye, Ocular Surface Disease, Cataract Surgery, Eyes Dry Feeling of
- Trial name
- NCT07796178
- Testing
- Lacrifill, Saline
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Eye Research Associates, LLC
Dry Eye, Vision Disorders
Visual Quality Change of Eyes Implanted With Diffractive Multifocal Intraocular Lens After Cataract Surgery
In this study, the investigators examined the subjective visual quality including LogMAR uncorrected distance visual acuity (UCDVA), best corrected distance visual acuity (BCDVA),uncorrected intermediate visual acuity (UCIVA)…
- Conditions
- Dry Eye, Vision Disorders, Quality of Life
- Trial name
- NCT02234635
- Testing
- Diffractive multifocal IOLs group
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Wenzhou Medical University
Dry Eye, Sjogren's Syndrome
Comparative Study of Thymosin Beta 4 Eye Drops vs. Vehicle in the Treatment of Severe Dry Eye
Severe dry eye is a debilitating ocular disease resulting in loss of vision, reduced day-to-day function and significant discomfort.
- Conditions
- Dry Eye, Sjogren's Syndrome, Graft vs. Host Disease
- Trial name
- NCT01393132
- Testing
- Thymosin Beta 4 eye drops, Vehicle Control
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Michigan Cornea Consultants, PC
Dry Eye Disease
A Study to Investigate the Effect of 0.003% AR-15512 on Subjects With Dry Eye Disease
The purpose of this study is to evaluate the effect of AR-15512 ophthalmic solution 0.003% (0.003% AR-15512) on ocular surface characteristics of subjects with dry eye disease (DED).
- Trial name
- NCT06544694
- Testing
- 0.003% AR-15512 ophthalmic solution, Artificial Tears
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Alcon Research
Dry Eye Syndromes, HIV Seropositivity
Topical Cyclosporine for the Treatment of Dry Eye in Patients Infected With the Human Immunodeficiency Virus
This study evaluates the use of topical cyclosporine 0.05% and sodium carboxymethylcellulose 0.5% for the treatment of dry eye disease in patients infected with the human immunodeficiency virus.
- Trial name
- NCT00797030
- Testing
- cyclosporine and sodium carboximethycellulose, sodium carboximethycellulose
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Dry Eye
Point of Care Test of LTA Level in Tear Fluid, Measured With a POCT Test, in DE Patients Following IPL Treatment
To quantify and compare tear levels of Intense pulsed light (IPL) and traditional dry eye clinical tests in dry eye patients before and after Intense pulsed light (IPL) treatment.
- Trial name
- NCT06269237
- Testing
- M22
- Volunteers
- 30 people
- Sponsor
- He Eye Hospital
Dry Eye
Prospective Health Assessment of Cataract Patients' Ocular Surface
This study will determine the incidence and severity of dry eye in patients undergoing cataract surgery as determined by grade on the International Task Force (ITF) scale.
- Trial name
- NCT01016405
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Innovative Medical
Dry Eye Syndromes
Management of Signs and Symptoms Associated With Dry Eye Disease
A prospective randomized, and controlled study to compare the effectiveness of PROKERA® SLIM plus standard of care (SOC) in the PROKERA® SLIM Arm to SOC alone in the Control Arm.
- Trial name
- NCT04015219
- Testing
- Self retained cryopreserved amniotic membrane, lifitegrast ophthalmic solution
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- BioTissue Holdings, Inc
Dry Eye Syndrome
Comparison of Autologous Serum and Umbilical Cord Serum Eyedrops for Dry Eye Syndrome
To compare the therapeutic effect between autologous serum and umbilical cord serum eyedrops in the treatment of severe dry eye syndrome.
- Trial name
- NCT00442273
- Testing
- Umbilical cord serum eyedrops, Autologous serum eyedrops
- Where
- South Korea
- Sponsor
- Chonnam National University Hospital
Dry Eye
MiBo ThermoFlo Lid Temperature Evaluation
This study is a prospective, contralateral, single-site, single-visit unmasked evaluation of external and internal eyelid temperature after treatment with the MiBo ThermoFlo.
- Trial name
- NCT03787212
- Testing
- MiBo ThermoFlo, Bruder Mask
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Dry Eye, Tear Film
Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome
With the potential to address evaporative dry eye, Liposic and Tears Naturale Forte have been developed in which phospholipid liposomes are delivered to the tear film via the surface of the closed eyelid.
- Conditions
- Dry Eye, Tear Film, Lipid Layer, Liposic
- Trial name
- NCT03211351
- Testing
- Liposic, Tears Naturale Forte
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Huaxia Eye Hospital Group
Dry Eye Syndromes
Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry Eye
The objectives of this study are twofold To evaluate the safety and efficacy of 0.1% AGN-195263 administered twice daily compared to its vehicle in patients with evaporative dry eye (EDE) To evaluate the systemic pharmacokinetics…
- Trial name
- NCT02815293
- Testing
- AGN-195263, Vehicle
- Where
- 29 sites in United States
- Volunteers
- 36 people
- Sponsor
- Allergan
Dry Eye Syndromes
Soothe Versus Refresh
To determine the ocular efficacy and safety of Soothe and Refresh Tears.
- Trial name
- NCT00284999
- Testing
- Soothe, Refresh Tears
- Where
- 3 sites in United States
- Volunteers
- 33 people
- Sponsor
- Pharmaceutical Research Network