Clinical trials: Dry Eyes Chronic
Ocular Graft-versus-host Disease
Allogeneic Platelet Lysate Eye Drops for the Treatment of Severe Chronic Ocular Graft-versus-host Disease
The study evaluates the efficacy and safety of allogeneic platelet lysate eye drops in patients with severe ocular graft versus host disease refractory to conventional systemic and local treatments.
- Trial name
- NCT05311514
- Testing
- Allogeneic platelet lysate eye drops
- Where
- Russia
- Volunteers
- 38 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Dry Eye
Clinical Characteristics of Patients Developing Chronic Dry Eye After Refractive Surgery
In recent years, many scholars have studied the ocular surface damage of patients with dry eye disease（DED）after FS-LASIK, but there has been a lack of comprehensive observation and research on the relationship and difference…
- Trial name
- NCT05600985
- Testing
- FS-LASIK
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Dry Eye, Dry Eyes Chronic
Switching From Xiidra to TRYPTYR
To determine the efficacy of switching participants who are being treated with Xiidra to acoltremon 0.003%. Hypothesis: Switching to acoltremon 0.003% will greatly improve the signs and symptoms of participants who were being…
- Conditions
- Dry Eye, Dry Eyes Chronic, Dry Eye Syndromes, Eye Diseases
- Trial name
- NCT07267481
- Testing
- acoltremon 0.003%
- Volunteers
- 100 people
- Sponsor
- Southern College of Optometry
Dry Eye, Dry Eye Syndromes
Effect of Lifitegrast 5% on Tear Film Markers
The purpose of this study is to assess the duration of time (in weeks) for improvement in objective dry eye markers for people who are placed on lifitegrast 0.5% (Xiidra®), an FDA-approved therapy for dry eyes.
- Conditions
- Dry Eye, Dry Eye Syndromes, Dry Eyes Chronic
- Trial name
- NCT03952481
- Testing
- Lifitegrast 5% Ophthalmic Solution
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Diabetic Foot Ulcer (DFU), Ocular Disorder
Air-Dried Human Amniotic Membrane Terminally Sterilized by Gamma Irradiation for Multidisciplinary Clinical Application
This prospective interventional clinical study aims to evaluate the safety and therapeutic efficacy of air-dried human amniotic membrane (hAM) sterilized using different doses of gamma irradiation for regenerative medical…
- Conditions
- Diabetic Foot Ulcer (DFU), Ocular Disorder, Pterygium
- Trial name
- GAMMA-AM (NCT07466576)
- Testing
- Air-Dried Human Amniotic Membrane (AD-hAM)
- Where
- Libya
- Volunteers
- 2 people
- Sponsor
- Libyan Center for Biotechnology Research
Dry Eye, Dry Eyes Chronic
Study to Evaluate the Safety and Tolerability of PRO-190 Ophthalmic Solution Compared to Systane Ultra® on the Ocular Surface.
This is a phase I clinical study to evaluate the safety and tolerability of PRO-190 ophthalmic solution through the incidence of unexpected adverse events, changes in Best Corrected Visual Acuity (BCVA), changes in ocular surface…
- Conditions
- Dry Eye, Dry Eyes Chronic, Dry Eye Syndromes
- Trial name
- NCT06379685
- Testing
- PRO-190, Systane Ultra®
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.