Clinical trials: Drying Time
Meibomian Gland Dysfunction, Dry Eye Syndromes
Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients
This observational study aims to assess the frequency and severity of Meibomian Gland Dysfunction (MGD) and associated ocular surface changes in patients with systemic autoimmune rheumatic diseases compared with healthy…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Rheumatoid Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07810569
- Volunteers
- 150 people
- Sponsor
- Assiut University
Dry Eye Syndrome
Assessment of Tear Film Thickness by Optical Coherence Tomography in Healthy Subjects and Subjects With Dry Eye Disease
Dry eye syndrome (DES) is a highly prevalent ocular condition with severe consequences for the patients reaching from ocular discomfort in its simplest form up to visual impairment and corneal ulceration in severe cases.
- Trial name
- NCT01753596
- Testing
- GENTEAL HA® Eye Drops (NOVARTIS, Switzerland), Physiological Sodium Chloride solution (0,9%)
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dry Eye
Analysis of the Diagnostic Performance of LacryDiag, a New Analyzer of the Ocular Surface in the Dry Eye
LacryDiag is a new Conformity European (CE) marked diagnostic imaging device devoted to the analysis of the ocular surface. It is an "all in one" device that provides 4 data: non-invasive break-up time (Non-Invasive Break-Up-Time…
- Trial name
- LACRYMOSA (NCT04093037)
- Testing
- Time #1: Non Invasive Break-Up Time (NIBUT), Time #2: MicroInstillation Break-Up Time (MIBUT) + Oxford score, Time #3: Standard Break-Up Time (SBUT)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Healthy
Optimal Time for In-situ Dry Needling to Affect the Autonomic Nervous System
Assessing for optimal time dry needles need to remain inside the body to have positive effect on the nervous system
- Trial name
- NCT03728751
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Florida Gulf Coast University
Visual Fatigue, Dry Eye
Evaluation of New Color Temperature Adjustment Mode in Preventing Dry Eye and Visual Fatigue
The purpose of this study was to investigate the effects of visual fatigue and dry eye level under different correlated color temperature modes, and to evaluate the effect of new designed dynamic color temperature change modes on…
- Trial name
- NCT07201493
- Testing
- color temperature change mode
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beijing Tongren Hospital
Aqueous Tear Deficiency, Meibomian Gland Dysfunction of Bilateral Eyes (Disorder)
Eyelid Androgen Treatment in Dry Eye
The purpose of this research study is to evaluate the effectiveness and safety of applying androgen sex hormone (i.e., testosterone) gel on the eyelids in the treatment of dry eye patients.
- Trial name
- NCT06154200
- Testing
- Testosterone gel 4.5%, Vehicle gel
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Incubator Stay, Total Blastulation
Impact of Dry vs Humidified Culture Conditions on Blastocyst Development and Aneuploidy: A Time-lapse Sibling Oocyte Study
IVF incubators are essential for maintaining the micro-environment required for embryo development. Incubator technology has progressed from early humidified box systems to benchtop and now time-lapse platforms, driving the…
- Conditions
- Incubator Stay, Total Blastulation, Blastocyst Quality, Biopsy Rate
- Trial name
- NCT07270250
- Testing
- K- system incubator
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Dry Eye
Management of DE With IPL in Combination With DQS
Intense pulsed light (IPL) has been reported to improve signs and symptoms of dry eye (DE). Additionally, meibomian gland secretion of lipids has been observed to improve through the use of IPL.
- Trial name
- NCT05694026
- Testing
- Intense pulsed light, Diquafosol tetrasodium
- Where
- China
- Volunteers
- 360 people
- Sponsor
- He Eye Hospital
Pharmacokinetics
A Study to Estimate the Time Course of PF-00241939 Concentration in the Blood Following Dosing by Oral Inhalation From Dry Powder Inhalers
The purpose of this study is to investigate the time course of PF-00241939 concentrations in the blood following dosing by oral inhalation using dry powder inhalers.
- Trial name
- B0871003 (NCT00867282)
- Testing
- Treatment A, Treatment B
- Where
- Singapore
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer
Dry Eye
Comparative Efficacy of SYSTANE® ULTRA vs Optive™ in Improving Tear Film Break-up Time
The primary objective of this study is assess the Tear Film break-up time (TBUT) in mild to moderate dry eye subjects.
- Trial name
- NCT01417013
- Testing
- Systane Ultra, Optive
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alcon Research
Dry Eye Disease
The Relationship of Residence Time and Visual Effect of Optive and Systane in Dry Eye Subjects
The benefits of artificial tears to relieve dry eye symptoms include, but are not limited to: stabilizing the tear film layer, fluid supplement action, improving visual acuity, and comfort.
- Trial name
- NCT00553579
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Bronchiectasis
Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE)
The purpose of this study is to evaluate if the time to first pulmonary exacerbation of bronchiectasis or its frequency can be prolonged by inhalation of ciprofloxacin for 28 days every other 28 days or for 14 days every other 14…
- Trial name
- RESPIRE 2 (NCT02106832)
- Testing
- Ciprofloxacin (BAYQ3939) dry powder for inhalation
- Where
- 207 sites in United States, Argentina and 23 more
- Volunteers
- 521 people
- Sponsor
- Bayer
Dry Mouth
Duration of Effect of Biotene Spray in Patients With Dry Mouth
To determine the duration of effect of a single dose of Biotène Moisturizing Mouth Spray in subjects who complain of a clinically dry mouth. The effect of the product will be compared to a control spray (water).
- Trial name
- NCT03663231
- Testing
- Biotene
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Rochester
Dry Eye, Tear Break-Up Time
Compare the Clinical Efficacy of 3% Diquafosol and 0.1% Hyaluronic Acid in Patients with Dry Eye After Trans-PRK
The prevalence of refractive ametropia is rising year by year. Refractive surgery has become the main approach for adults to correct refractive ametropia, and postoperative complications have aroused extensive attention from…
- Trial name
- NCT06852105
- Testing
- 3% Diquafosol Sodium Eye Drops, 0.1% hyaluronic acid
- Volunteers
- 76 people
- Sponsor
- He Eye Hospital
Healthy, Dry Eye
Punctal Plug Study to Determine the Safety and Retention Times of Various Lengths of Canalicular Stents in Volunteers
The purpose of this study was to determine the safety and retention times of two different lengths (10 mm and 20 mm) of the MINI MONOKA canicular stent when inserted in the eye for up to three months in subjects with or without…
- Trial name
- NCT00743249
- Testing
- MINI MONOKA canalicular stent, 10 mm, MINI MONOKA canalicular stent, 20 mm
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alcon Research
ABPA
Study to Evaluate Itraconazole Administered as Inhaled Dry Powder in Adults With Asthma and ABPA
The goal of this clinical trial is to learn about PUR1900 as an inhaled, antifungal therapeutic for the treatment of allergic bronchopulmonary aspergillosis (ABPA) in patients with asthma.
- Trial name
- NCT05667662
- Testing
- Itraconazole Powder
- Where
- 18 sites in United States, Australia and 2 more
- Volunteers
- 8 people
- Sponsor
- Pulmatrix Inc.
Dry Eye
The Effect of SYSTANE® BALANCE on Tear Film Break Up Time in Dry Eye Subjects
The purpose of this study was to evaluate the ability of SYSTANE® BALANCE dosed 4 times a day for 30 days to increase non-invasive tear film break up time over baseline, compared to a saline control, in dry eye subjects with…
- Trial name
- NCT01718028
- Testing
- Propylene glycol 0.6% ocular emulsion, Sodium chloride 0.9% saline solution
- Where
- Argentina
- Volunteers
- 51 people
- Sponsor
- Alcon Research
Dry Eye Syndromes
Treatment of Dry Eye With Supplements
Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response on the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential…
- Trial name
- NCT01364311
- Testing
- Vitamac® Tag and Nacht capsules
- Where
- Austria
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Dry Eye
Evaluation of Extended Tear Film Break Up Time (TFBUT) With an Ocular Emulsion
The primary objective of this investigation will be to quantify the increase in tear film break-up time (TFBUT) associated with the instillation of a single eyedrop of an Ocular Emulsion in dry eye sufferers.
- Trial name
- NCT01368198
- Testing
- Systane Balance Lubricating Eye Drops, OPTIVE™
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Dry Eye
Tear Film Break-Up Time Evaluation of FID 114657
To evaluate the effects of FID 114657 on tear film break-up time in dry eye patients.
- Trial name
- NCT01023464
- Testing
- FID114657, SootheXP Emollient (Lubricant) Eye Drops
- Volunteers
- 38 people
- Sponsor
- Alcon Research