Clinical trials: Dryness of Mouth
Sjogren's Syndrome
Efficacy and Safety of Baricitinib in Sjogren's Syndrome
The investigators had observed that baricitinib was effective and safe in active pSS patients in a pilot study. So the investigators plan to conduct a multi-center, prospective, open-label, randomized study to evaluate the…
- Trial name
- NCT05016297
- Testing
- Baricitinib, Hydroxychloroquine
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Peking Union Medical College Hospital
Sjogren Syndrome, Sjogren Disease
TREATMENT OF VAGINAL DRYNESS IN SJÖGREN'S DISEASE WITH CO2-LASER VERSUS TOPICAL PROMESTRIENE
Sjögren's disease (SjD) is a chronic, immune-mediated, systemic inflammatory disease characterized mainly by involvement of the salivary and lacrimal glands, causing symptoms of sicca syndrome.
- Conditions
- Sjogren Syndrome, Sjogren Disease, Primary Sjogren Syndrome
- Trial name
- VaLS (NCT07153276)
- Testing
- Fractional CO2 laser (vaginal), Promestriene Vaginal
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Cicatrizing Conjunctivitis, Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum
Minor Salivary Gland Transplantation for Cicatrizing Conjunctivitis
This is a prospective study that aimed to observe the therapeutic effects of minor salivary gland transplantation for cicatrizing conjunctivitis patients.
- Conditions
- Cicatrizing Conjunctivitis, Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum, Sjogren Syndrome, Mucous Membrane Pemphigoid
- Trial name
- NCT03839069
- Testing
- minor salivary gland transplantation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Keratoconjunctivitis Sicca, Sjogren's Syndrome
Treatment of Dry Eye Syndrome With Cyclosporin A Eye Drops
This study will examine whether cyclosporin A eye drops alleviate dry eye syndrome, a disorder of tear deficiency or excessive tear evaporation. The condition damages the surface of the eye and causes discomfort.
- Trial name
- NCT00001731
- Testing
- Cyclosporin A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Eye Institute (NEI)
Sjogren's Syndrome
Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue
Our research contributes to the understanding of some of the basic biology of the salivary glands. The etiology and many of the pathomechanisms of Sjögren's syndrome are unknown.
- Trial name
- NCT00543166
- Testing
- dehydroepiandrosterone
- Where
- Finland
- Volunteers
- 107 people
- Sponsor
- University of Helsinki
Dry Eye Syndrome
Phase 2 Study to Evaluation the Safety and Efficacy of Orally Administered KL7016 in Patients With Dry Eye Syndrome
This is a controlled study to determine the effectiveness and safety of KL7016 in the treatment of adult patients with dry eye syndrome (DES).
- Trial name
- NCT02092207
- Testing
- KL7016 900mg, KL7016 600mg
- Where
- 9 sites in South Korea
- Volunteers
- 147 people
- Sponsor
- Yungjin Pharm. Co., Ltd.