Clinical trials: Duodenal Cancer
Neuroendocrine Tumours
68-Ga-labeled Octreotide Analogues PET in Duodenal-pancreatic Neuroendocrine Tumours
The diagnostic work-up of patients suspected of having neuroendocrine tumours (NETs) has traditionally been a challenging issue.
- Trial name
- NCT01673906
- Testing
- Diagnostic work up
- Where
- 21 sites in Austria, Italy
- Volunteers
- 142 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Familial Adenomatous Polyposis
A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis
The purpose of this study is to determine the efficacy and safety of a personalized surveillance and intervention protocol for duodenal and gastric polyposis in patients with familial adenomatous polyposis (FAP)
- Trial name
- NCT04677998
- Testing
- Personalized surveillance and intervention protocol
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Adenoma
Prophylactic Octreotide to Prevent Post Duodenal EMR and Ampullectomy Bleeding
Our hypothesis is that prophylactic administration of 5 days of Octreotide following EMR or ampullectomy in patients with duodenal and ampullary adenomas greater than or equal to 10mm.
- Trial name
- NCT02032784
- Testing
- octreotide, No Octreotide
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- AdventHealth
Pancreatic Neoplasms, Biliary Tract Neoplasms
Nonstented Stump-closed vs Duct-to-Mucosa Pancreaticojejunostomy After Pancreaticoduodenectomy
Pancreaticojejunostomy is the key procedure of pancreaticoduodenectomy. The aim of our study is to investigate a new pancreaticojejunal (PJ) anastomosis procedure named "nonstented stump-closed pancreaticojejunostomy" in…
- Conditions
- Pancreatic Neoplasms, Biliary Tract Neoplasms, Pancreatitis, Chronic, Duodenal Neoplasms
- Trial name
- NCT01731821
- Testing
- pancreaticojejunostomy
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Fudan University
Pancreatic Tumor, Gastric Tumor
Comparing the Efficacy of Endoscopic FNA vs FNB in Diagnosing Solid Gastrointestinal Lesions
The purpose of this study is to determine if fine needle aspiration or fine needle biopsy is more efficacious and cost-effective than the other while maintaining diagnostic accuracy in the setting of solid gastrointestinal…
- Conditions
- Pancreatic Tumor, Gastric Tumor, Esophageal Tumor, Lymphadenopathy
- Trial name
- NCT01698190
- Testing
- Endoscopic ultrasound guided needle tissue acquisition.
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Stony Brook University
Ampullary Cancer, Duodenal Cancer
Interventional Endoscopy Database for Pancreatico-biliary, Gastrointestinal and Esophageal Disorders
Our institution performs therapeutic ERCP (Endoscopic retrograde cholangiopancreatography ), Endoscopic Ultrasound (EUS) and Interventional Endoscopy in around 1000 patients a year.
- Conditions
- Ampullary Cancer, Duodenal Cancer, Bile Duct Cancer, Bile Duct Disorders
- Trial name
- NCT01438385
- Testing
- Interventional Endoscopy
- Where
- United States
- Volunteers
- 12,000 people
- Sponsor
- Weill Medical College of Cornell University
Helicobacter Infection
Comparison of Sequential or Concomitant Therapy for Helicobacter Pylori Infection
Helicobacter pylori is a bacteria that infects the lining of the stomach and is associated with ulcers. Helicobacter pylori may also increase the long-term risk of developing certain forms of gastric cancer.
- Trial name
- 960025 (NCT00656968)
- Testing
- 10-day sequential treatment, 10-day concomitant therapy
- Where
- 2 sites in Taiwan
- Volunteers
- 232 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Colorectal Cancer, Colorectal Adenoma
Volatile Markers in Digestive Cancer
The study is aimed to determine the potential of volatile marker testing for identification of gastrointestinal cancers (in particular - colorectal and gastric cancers), the related precancerous lesions in the stomach and colon.
- Conditions
- Colorectal Cancer, Colorectal Adenoma, Gastric Cancer, Peptic Ulcer Disease
- Trial name
- VOLGACORE (NCT02332213)
- Testing
- Breath sampling for volatile marker detection, Upper endoscopy with biopsies, Colonoscopy with biopsies or lesion removal when required
- Where
- 2 sites in Latvia, Lithuania
- Volunteers
- 2,022 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Duodenal Diseases
Endoscopic Characteristics of Duodenal and Ampullary Lesions
The purpose is to investigate whether polyps that look different at endoscopy, have formed via different mutations and have different risks of turning into cancer.
- Trial name
- DUO/AMP-LST (NCT01556399)
- Testing
- Tissue Sampling
- Where
- Australia
- Volunteers
- 350 people
- Sponsor
- Professor Michael Bourke
Pancreatic Cancer, Pancreas Cancer
Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy
The purpose of this study is to prospectively determine the effects of administering proton pump inhibitors (PPIs) following pancreaticoduodenectomy on postoperative outcomes.
- Conditions
- Pancreatic Cancer, Pancreas Cancer, Ampullary Cancer, Pancreas Neuroendocrine Tumor
- Trial name
- NCT05251233
- Testing
- Pantoprazole
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Washington University School of Medicine
Barrett Esophagus, Esophageal Neoplasms
Feasibility of Multi-Spectral Endoscopic Imaging for Detection of Early Neoplasia in Barrett's Oesophagus
Multispectral imaging represents an exciting new field of investigation in endoscopic research. Multispectral imaging uses a specialised camera to detect multiple colours, allowing us to build a rough spectrum from each point in…
- Conditions
- Barrett Esophagus, Esophageal Neoplasms, Reflux Esophagitis
- Trial name
- MuSE (NCT03388047)
- Testing
- Endoscopy with Polyscope (Polydiagnost TM) coupled with Multi-Spectral Imaging light-source
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Cambridge
Barrett Esophagus, Gastroesophageal Reflux Disease
GCC Agonist Signal in the Small Intestine
This early phase I trial studies the guanylyl cyclase C (GCC) agonist effect on cGMP signal in duodenal tissue. Plecanatide and linaclotide are drugs approved by the Food and Drug Administration for the treatment of conditions…
- Conditions
- Barrett Esophagus, Gastroesophageal Reflux Disease, Malignant Digestive System Neoplasm
- Trial name
- NCT05107219
- Testing
- Biopsy, Biospecimen Collection, Esophagogastroduodenoscopy
- Where
- 4 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Wisconsin, Madison
Gastric Cancer
Laparoscopy-assisted Proximal Gastrectomy Versus and Laparoscopy-assisted Total Gastrectomy
The choice of surgical strategy for patients with proximal gastric cancer is controversial mainly because proximal gastrectomy is infamous for high rates of reflux symptoms and anastomotic stricture.
- Trial name
- PRAPT (NCT01433861)
- Testing
- Laparoscopy-assisted gastrectomy
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- Seoul National University Bundang Hospital
Tumor of Esophagus, Stomach and Duodenum
The Effect of Chemotherapy and Surgery for Cancer on Exercise Capacity
Neoadjuvant chemotherapy (NAC) prior to surgery for upper gastrointestinal (oesophageal and gastric) cancer is associated with improved survival.
- Trial name
- NCT01325883
- Where
- United Kingdom
- Volunteers
- 253 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Adenoma, Villous
Long-term Outcomes of Endoscopic Resection (ER) of Lesions of the Duodenum and Ampulla
This research project, 'Outcomes of endoscopic resection of mucosal and submucosal lesions in the duodenum and ampulla'. The research project is aiming to determine the most effective and safe way to remove such lesions.
- Trial name
- OERDA (NCT02306603)
- Testing
- Endoscopic Mucosal Resection
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Professor Michael Bourke