Clinical trials: Duration of Operation
Postoperative Pulmonary Complications, One Lung Ventilation
The Effect of Single Lung Ventilation Duration on Postoperative Pulmonary Complications in Thoracic Surgery
This observational study investigates the relationship between the duration of single-lung ventilation (SLV) and the incidence of postoperative pulmonary complications (PPCs) such as pneumonia, pneumothorax, hemothorax, acute…
- Conditions
- Postoperative Pulmonary Complications, One Lung Ventilation, Ards, Postoperative Pulmonary Atelectasis
- Trial name
- NCT07100860
- Testing
- One-Lung ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Delirium - Postoperative, Postoperative Cognitive Dysfunction (POCD)
Value of the Time-Weighted Average (TWA) of Mean Arterial Pressure (MAP) and Cerebral Oximetry (rSO₂) as Predictors of Postoperative Tissue Perfusion Impairment in Patients Undergoing Cardiac Surgery
Neurological problems after heart surgery are common and include confusion, memory loss, and difficulty thinking clearly. These issues may appear hours or days after surgery and can negatively affect recovery.
- Conditions
- Delirium - Postoperative, Postoperative Cognitive Dysfunction (POCD), Postoperative Acute Kidney Injury, Postoperative Morbidity
- Trial name
- NCT07510711
- Testing
- Continuous intraoperative monitoring of MAP and rSO₂; observational study with no therapeutic intervention.
- Volunteers
- 120 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Hepatocellular Carcinoma
A Trial of Adjuvant Transarterial Chemoembolization (TACE) for Preventing Tumor Recurrence After Liver Resection
The aim of this study is to analyze the therapeutic effect of adjuvant TACE after resection.Patients receiving curative resection (R0) were randomized to postoperative TACE group and no TACE group.
- Trial name
- NCT00820053
- Testing
- epirubicin and lipiodol
- Where
- China
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Eastern Hepatobiliary Surgery Hospital
Postoperative Pain
Dexmedetomidine in Erector Spinae Block in Postoperative Analgesia
60 female patients scheduled for breast cancer surgeries, allocated in 3 groups for erector spinae block with bupivacaine and erector spinae block with dexmedetomidine added to bupivacaine and control group.
- Trial name
- NCT04920669
- Testing
- erector spinae block with bupivacaine, erector spinae block with bupivacaine + dexmedetomidine
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Mohamed Elsayed Hassan
Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time
Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children
The investigators intend to study the safety and effectiveness of opioid free anesthesia compared to opioid anesthesia in ambulatory surgery in children, regarding postoperative pain, hemodynamic stability, agitation and…
- Conditions
- Effect of Anesthesia in Postoperative Pain, Effect of Anesthesia in Extubation Time, Effect of Anesthesia in Discharge Time From Postanesthesia Care Unit, Effect of Anesthesia in Postoperative Adverse Events
- Trial name
- NCT03979469
- Testing
- Ketamine, dexmedetomidine, fentanyl, remifentanil
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Athens General Children's Hospital "Pan. & Aglaia Kyriakou"
Colon Cancer
Personalizing Colorectal Cancer Medicine (ImmuCol2)
Colorectal cancers are the leading cancers for both sexes combined. They represent 15-20% of all cancers. This cancer has a severe prognosis, the survival rate at 5 years is around 55% and in France it is estimated, all…
- Trial name
- ImmuCol2 (NCT02274753)
- Where
- 9 sites in France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Non-operative Time, General Surgery, Above 18 Years of Age
Redesigned Process in the Operating Room
The main purpose of the study is to examine whether operating room (OR) efficiency will be improved by significantly decreasing non operative time.
- Trial name
- NCT01937247
- Testing
- Patients will be inducted in the induction room, Redesigned process, patient will be reversed with sugammadex 4mg/kg IV
- Where
- Lebanon
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Carcinoma, Non-small-cell Lung Cancer
Dynamic Changes of Circulating Tumor DNA in Surgical Lung Cancer Patients
Previous study showed circulating tumor DNA levels reflect the total systemic tumor burden. Circulating tumor DNA levels should decrease after complete surgery and could be increase as tumor recurrence.
- Conditions
- Carcinoma, Non-small-cell Lung Cancer, Lung Neoplasms
- Trial name
- NCT02965391
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking University People's Hospital
Achilles Tendon Rupture
Comparison of Therapeutic Effect of Different Brace Fixed Time After Novel Achilles Tendon Rupture Surgery
This study is a prospective randomized controlled clinical study. After the novel Achilles tendon rupture repaired , patients were randomly divided into 4 groups according to immobilisation duration of 0, 2, 4, and 6 weeks…
- Trial name
- NCT04956614
- Testing
- immobilisation duration
- Where
- China
- Volunteers
- 266 people
- Sponsor
- Peking University Third Hospital
Hypotension, Hemodynamic Instability
The "Hypotension Prediction Index" in Patients Undergoing Lung Surgery
The "Hypotension Prediction Index (HPI)" was established by the Edwards Lifescience Company (Irvine, California, USA) and is CE certified.
- Conditions
- Hypotension, Hemodynamic Instability, Renal Failure, Myocardial Injury
- Trial name
- NCT04149314
- Testing
- HPI based hemodynamic optimization algorithm
- Where
- Germany
- Volunteers
- 142 people
- Sponsor
- University of Giessen
Colorectal Cancer, Surgery
Randomized Controlled Trial for Retractor SPONGE Evaluation in Laparoscopic Colorectal Surgery
To achieve an adequate visual working field during laparoscopic colorectal surgery without disturbance of the small intestine, patients are positioned in Trendelenburg position.
- Trial name
- SPONGE (NCT02574013)
- Testing
- Endoractor®
- Where
- Netherlands
- Volunteers
- 188 people
- Sponsor
- St. Antonius Hospital
Perioperative Complication
Perioperative Morbidity in Elective Surgery Based on the Time of the Year
This is a retrospective cohort study using Electronic Privacy Identification Center (EPIC) database to evaluate if there are any differences in perioperative morbidity for elective surgery based on the time of the year surgery is…
- Trial name
- NCT02958293
- Volunteers
- 19,872 people
- Sponsor
- TriHealth Inc.
Emergency Surgery
Is TIme From adMission to surgEry an Independent Prognostic Factor for Survival of Patients With Gastro-intestinal Perforation Associated With Septic Shock: (TIME) An Italian Intersocietary Retrospective and Prospective Observational Trial
Gastro-intestinal perforation is a condition that can become life-threatening in case of appearance of systemic symptoms, sepsis-related peripheral hypoperfusion and single or multiple organ failure needing a prompt intervention…
- Trial name
- TIME (NCT04811755)
- Testing
- Surgical timing from ED admission to surgery
- Volunteers
- 3,276 people
- Sponsor
- San Luigi Gonzaga Hospital
Non Small Cell Lung Cancer
Real-Time Imaging to Improve Lung Cancer Diagnosis : Comparing Confocal Laser Endomicroscopy (CLE) With Standard Biopsy for Quicker and Safer Detection of Non-Small Cell Lung Cancer
The goal of this observational study is to evaluate whether confocal laser endomicroscopy (CLE) can improve the real-time diagnosis of non-small cell lung cancer (NSCLC) in patients undergoing bronchoscopic biopsy for suspected…
- Trial name
- SCORACLE (NCT07538947)
- Testing
- bronchoscopic navigation with CLE
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Central Hospital, Nancy, France
Pelvic Organ Prolapse, de Novo Stress Urinary Incontinence
CREDE Study: Intraoperative Crede Manoeuver Compared to Preoperative Prolapse Reduction Stress Test to Predict Postoperative de Novo Stress Urinary Incontinence (PONSUI) at the Time of Pelvic Organ Prolapse (POP) Surgery
The CREDE pilot randomized study will compare the intraoperative Crede manoeuver (M1) to preoperative prolapse (POP) reduction cough stress test (M2) for the prediction and prevention of PONSUI.
- Conditions
- Pelvic Organ Prolapse, de Novo Stress Urinary Incontinence, Stress Urinary Incontinence
- Trial name
- NCT04087642
- Testing
- Intraoperative Crede manoeuver, Preoperative prolapse reduction cough stress test
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pharmacological Action
The Effect of Tranexamic Acid. A Randomised Study of Patients Undergoing Elective Lumbar Spine Surgery.
In this randomized double blind placebo controlled study of tranexamic acid during minor spinal surgery, mean postoperative blood loss in the patients who received TXA was statistically significantly lower compared to placebo.
- Trial name
- NCT03714360
- Testing
- Tranexamic Acid, Sodium Chloride 0,9%
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Mikkel Østerheden Andersen
First-attempt Success Rate of Real-time Ultrasound-guided Thoracic Epidural Catheter Placement
Application of Real-time Ultrasound Guidance in Thoracic Epidural Catheter Placement
The goal of this clinical trial is to assess the success rate of real-time ultrasound-guided thoracic epidural catheter placement at the first attempt in patients who will undergo thoracic or abdominal surgeries.
- Trial name
- NCT07100769
- Testing
- Real-time ultrasound-guided thoracic epidural placement
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Postoperative Nausea and Vomiting
Costs of Postoperative Nausea and Vomiting in Ambulatory Surgery Patients
This is an observational study with the goal of determining the costs of nausea and vomiting in ambulatory patients after surgery from the US societal perspective.
- Trial name
- NCT00858949
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cleveland Clinic
Ventilator Weaning
Comparative Study of Duration of Respiratory Weaning Between Adaptive Support Ventilation and Succession of Controlled Ventilation Then Spontaneous Ventilation for Patients After Surgery
This is a comparative study of duration of respiratory weaning between adaptive support ventilation and succession of controlled ventilation then spontaneous ventilation for patients after surgery.
- Trial name
- NCT00313326
- Testing
- Adaptative Support Ventilation
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Clermont-Ferrand
Thyroid, Thyroid Cancer
Parathyroid Vascularization During Total Thyroidectomy Using Indocyanine Green Angiography
Prospective, observational, single-center study about the use of indocyanine green angiography during total thyroidectomy. The main objective of the study is to identify a quantitative score of parathyroid vascularization as an…
- Conditions
- Thyroid, Thyroid Cancer, Hypoparathyroidism, Vascularization
- Trial name
- ANGIO_PARA (NCT05328076)
- Testing
- Indocyanine green, SPY Portable Handheld Imaging (SPY-PHI)
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- IRCCS San Raffaele