Clinical trials: Duration of Response
Cytomegalovirus Infections
Kinetics of Response of Cytomegalovirus With Ganciclovir Treatment Using Quantitative Real-Time PCR
The overall purpose of this research is to develop and use a blood test to better understand how quickly the viral drug ganciclovir works to clear infection with the CMV virus (Cytomegalovirus) when it occurs.
- Trial name
- NCT00004573
- Testing
- ganciclovir
- Where
- United States
- Sponsor
- National Center for Research Resources (NCRR)
Old Age
Breaking-up Sedentary Time and 2 Weeks Detraining
Regularly interrupting sedentary behavior (SB) with activity breaks may attenuate postprandial glucose (PPG) excursions and improve glycemic control.
- Trial name
- NCT04142346
- Testing
- Sitting + moderate intensity breaks
- Where
- Portugal
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Multiple Myeloma
Non-interventional Study on Time to Response and Quality of Life in Relapsed/Refractory Multiple Myeloma When Treated With Lenalidomide in Second Line
The purpose of this study is to quantify the burden of treatment in relapsed or refractory multiple myeloma in patients receiving lenalidomide after one prior treatment for myeloma.
- Trial name
- NCT01430546
- Where
- Sweden
- Volunteers
- 133 people
- Sponsor
- Hareth Nahi
AKI, Sepsis
Effect of CRRT Duration on Solute Removal
The only FDA approved treatment for acute kidney injury(AKI) for patients is Dialysis-also known as renal replacement therapy(RRT). Continuous RRT(CRRT) is the preferred method in the ICU.
- Trial name
- NCT04458571
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Colorado, Denver
Major Depressive Episode
Retrospective Observational Study DIANA Study
This Non-Interventional Study (NIS) is intended to evaluate the duration of treatment with an initial antidepressant taken as monotherapy in patients in whom treatment was changed because of suboptimal response at physician's…
- Trial name
- DIANA (NCT01976793)
- Where
- 8 sites in Russia
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Cancer
Demographics, Clinical Outcomes, and Physician Attitudes in Patients Who Have Received The MiCK Assay (CorrectChemo)
Recently an automated test for measuring cancer cell death in the presence of chemotherapy has been developed. This test has been called the MiCK assay during the ten year development phase and is now called Correct Chemo.
- Trial name
- NCT02137811
- Testing
- MICK Assay
- Where
- 2 sites in United States, Canada
- Sponsor
- Pierian Biosciences
Parkinson's Disease
An Extension of Istradefylline in Parkinson's Disease Patients Who Have Completed Studies 6002-EU-007, 6002-US-013 or 6002-US-018
This is a 1-year, open-label, long-term safety extension for patients who have completed prior istradefylline studies 6002-EU-007, 6002-US-013 or 6002-US-018.
- Trial name
- NCT00199368
- Testing
- Istradefylline ( KW-6002)
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- Kyowa Kirin, Inc.
Healthy
Effects of Time-Restricted Fasting on the Postprandial Glycemic Responses
The goal of this clinical trial is to investigate whether fasting timing has a significant effect on postprandial glycemic responses in healthy adults. The main questions it aims to answer are: 1.
- Trial name
- NCT05913635
- Testing
- Consumption of lunch and dinner, with no breakfast, Consumption of breakfast and lunch, with no dinner
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fudan University
Quality Control, Validation Study
Comparison of Four Methods for Entering the Gap Position of Landolt Cs
The aim of this study is to investigate and compare the validity of four different input methods for Landolt Cs, i.e. the proportion of correct gap positions in relation to the total number of performances.
- Trial name
- LC_Entry (NCT04299659)
- Testing
- Landolt C entry method
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aalen University
Pre Diabetes, Postprandial Hyperglycemia
Evaluating the Acute Glycemic Response to Different Strategies of Breaking Up Sedentary Time
This study aims to determine the most effective strategy of reducing sedentary behavior to improve health. Specifically, we aim to answer the following questions: (a) To determine if there is a significant difference in acute…
- Trial name
- NCT04144920
- Testing
- CS: Continuous sitting, HFLD: HIgh frequency, low duration standing breaks, LFHD: Low frequency, high duration standing breaks
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Arizona State University
Sepsis
Dexmedetomidine for Sepsis in ICU Randomized Evaluation Trial
Background: Dexmedetomidine, a highly selective arfa2-adrenergic agonist, is known to be a unique sedative agent which causes less acute tolerance, drug addiction and withdrawal compared with gamma-aminobutyrate (GABA) agonists.
- Trial name
- DESIRE (NCT01760967)
- Testing
- Dexmedetomidine
- Where
- Japan
- Volunteers
- 203 people
- Sponsor
- Wakayama Medical University
Evidence of Adaptation to Dietary Exposure to Fructans
Pilot Study of the Effect of Fructans on Fermentation in the Colon & Transit
Some carbohydrates (complex sugars) which are found in grains, fruit and vegetables, cannot be digested by humans. When eaten they pass through the small bowel to the large bowel, or colon.
- Trial name
- PERFECT (NCT01963364)
- Testing
- Inulin challenge, oligofructose supplement
- Where
- 2 sites in United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sepsis
Procalcitonin-guided Treatment on Duration of Antibiotic Therapy and Cost in Septic Patients
This clinical trial is aimed to show a procalcitonin-guided treatment algorithm may shorten duration of antibiotic therapy safely and cost-effectively in sepsis patients of Korean ICU.
- Trial name
- PRODA (NCT02202941)
- Testing
- Procalcitonin guided treatment, Conventional treatment
- Where
- 4 sites in South Korea
- Volunteers
- 62 people
- Sponsor
- Seoul National University Hospital
Acute Kidney Injury
Acute Kidney Injury in Severe Trauma
Acute kidney injury (AKI) represents a serious complication following severe injury associated with adverse outcome. Main goals of the presented study were to define the incidence of AKI and to evaluate the validity of AKI…
- Trial name
- NCT03433079
- Testing
- Neutrophil gelatinase-associated lipocalin (NGAL), Arterial lactate, Interleukin-6 (IL-6)
- Where
- Czechia
- Volunteers
- 81 people
- Sponsor
- University Hospital Ostrava
Physical Inactivity, Overweight or Obesity
eMOTION Formative Study
The eMOTION Study is a two-part ORBIT model phase 1 trial. The first part, called the Formative Study, will assess acceptability and feasibility of a novel physical activity intervention in adults at increased risk for cancer due…
- Conditions
- Physical Inactivity, Overweight or Obesity, Cancer
- Trial name
- NCT06125964
- Testing
- Intensity-Based Goals, Affect-Based Goals, TYPE/CONTEXT Enhancement
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Health Adult Subjects
Dose-response Effects of Dietary Nitrate on Running Time-to-exhaustion and Neuromuscular Fatigue: a Randomized Crossover Exploratory Pilot Study
Background: Dietary nitrate is a natural compound found in vegetables such as beetroot and leafy greens. Previous research suggests that consuming nitrate before exercise may improve endurance and physical performance.
- Trial name
- Nitrate TTE (NCT07735455)
- Testing
- Dietary Nitrate
- Where
- Spain
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Glabellar Frown Lines
Xeomin Treatment of Glabellar Lines Using OLD Versus COLD
This is a blinded, randomized study in the US to compare the duration response of two different concentrations of Xeomin in healthy female subjects with moderate to severe dynamic glabellar lines on maximum frown.
- Trial name
- NCT05305768
- Testing
- IncobotulinumtoxinA
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinical Testing of Beverly Hills
Vaccination; Infection
Study of the Impact of Time of Vaccination on Response to Influenza Vaccine in Patients With Chronic Renal Failure
Immune response to influenza vaccine in patients with chronic renal insufficiency.
- Trial name
- CHRONOVAX2 (NCT06907667)
- Testing
- Vaccine injection
- Where
- France
- Volunteers
- 735 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Respiratory Syncytial Virus Infections
A Study on the Safety and Immune Response to an mRNA-based RSV Investigational Vaccine in Healthy Adults Aged 18-45 Years
The purpose of this study is to assess the reactogenicity, safety and immune response of various formulations of the RSV mRNA investigational vaccine administered in healthy participants 18-45 years of age.
- Trial name
- NCT06573281
- Testing
- Investigational RSV vaccine 1, Investigational RSV vaccine 2, Investigational RSV vaccine 3
- Where
- 9 sites in United States, Australia and 1 more
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Physical Activity, Overweight or Obesity
eMOTION: Examining Implicit Attitudes in Physical Activity Engagement
This early-phase trial will test intervention strategies to influence implicit attitudes towards physical activity and determine whether changes in those mechanisms result in change in physical activity behavior among inactive…
- Conditions
- Physical Activity, Overweight or Obesity, Cancer
- Trial name
- NCT07044570
- Testing
- Physical Activity Goals mHealth Intervention, TYPE/CONTEXT enhancement, SAVOR enhancement
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- University of Southern California