Clinical trials: Dynamic Hyperinflation
COPD
The Changes in End Expiratory Lung Impedence Measured by EIT and End Expiratory Lung Volume Measured by Passive Expiratory in Controlled Mechanical Ventilated Exacerbation COPD Patients
The pathophysiological characteristics of respiratory failure on exacerbation of chronic pulmonary obstructive disease are the rapid deteriorate of respiratory symptoms, combined with aggravated flow limitation, gas trapping…
- Trial name
- NCT05585060
- Testing
- the changes of end expiratory lung impedence, the changes of end expiratory lung volume
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Bronchiectasis Adult
Predictors of Physical Activity Performance and Dynamic Hyperinflation in Patients With Bronchiectasis
Bronchiectasis is characterized by abnormal and irreversible airway dilation and can be caused by a wide variety of diseases, including congenital diseases, mechanical bronchial obstruction, respiratory infections, and…
- Trial name
- NCT04234789
- Testing
- cardiopulmonary exercise testing with dynamic hyperinflation maneuver, spirometry, pletysmography
- Where
- Brazil
- Volunteers
- 208 people
- Sponsor
- University of Sao Paulo General Hospital
Pulmonary Disease, Chronic Obstructive
Dynamic Hyperinflation In Mechanically Ventilated Chronic Obstructive Pulmonary Disease Patients
Chronic obstructive pulmonary disease is a common respiratory condition that is characterized by inflammation of the large and small peripheral airways , the alveoli and adjacent capillary networks.
- Trial name
- NCT03230617
- Testing
- Mechanical ventilator
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Chronic Obstructive Pulmonary Disease
Effects of Inhaled Corticosteroids in the Systemic Inflammation Induced by Exercise in Patients With COPD
Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary and systemic inflammation. The effect of inhaled corticosteroids (IC) on inflammation in COPD is controversial.
- Trial name
- NCT02209974
- Testing
- Fluticasone
- Where
- Spain
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Hospital Son Llatzer
Dynamic Hyperinflation
Dynamic Hyperinflation During Maximal Voluntary Ventilation in Healthy Subjects
Maximal Voluntary Ventilation (MVV) correlates well with maximal exercise capacity and is used to assess the ventilatory function during exercise in COPD (Chronic Obstructive Pulmonary Disease) patients.
- Trial name
- NCT02831465
- Testing
- Healthy Subjects
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Pulmonary Disease, COPD
Reducing Dynamic Hyperinflation Through Breathing Retraining
This study will compare the effects of exercise training and breathing retraining (using metronome tones) to exercise training only. Exercise training lasts 12 weeks.
- Trial name
- NCT01009099
- Testing
- breathing retraining, exercise training
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- US Department of Veterans Affairs
Chronic Obstructive Pulmonary Disease
The Effects of a Positive Expiratory Pressure (PEP) on Dyspnea and Dynamic Hyperinflation During Exercise in Chronic Obstructive Pulmonary Disease (COPD) Patients
From the relationship between pathophysiology of chronic obstructive pulmonary disease (COPD), dyspnea, and dynamic hyperinflation during ventilatory increasing, the investigators hypothesize that 1.
- Trial name
- NCT00741832
- Testing
- Conical Positive Expiratory Pressure Device (C-PEP), Control breathing
- Where
- Thailand
- Volunteers
- 11 people
- Sponsor
- Khon Kaen University
Chronic Obstructive Pulmonary Disease
Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in COPD
Pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen saturation in patients with chronic obstructive pulmonary disease (COPD) at rest.
- Trial name
- NCT01173328
- Testing
- Pursed-lip breathing, Normal Breathing
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal do Rio de Janeiro
COPD, Obesity
Effects of Obesity on COPD
The purpose of this study is to investigate whether obese COPD patients experience more or less discomfort in daily life. Furthermore the investigators will evaluate if body composition or body fat distribution has effects on…
- Conditions
- COPD, Obesity, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT06474858
- Where
- Netherlands
- Volunteers
- 166 people
- Sponsor
- Rijnstate Hospital
Pulmonary Disease, Chronic Obstructive
Efficacy of Self-titration of Ventilation in Overlap Syndrome (chronic Obstructive Pulmonar Disease + Sleep Apnea Syndrome ) with Dynamic Hyperinflation. EDIN-IDIN.
The combination of COPD and obstructive sleep apnea (OSA) can lead to undesirable interactions with the treatment approach. The investigators know that continuous positive airway pressure (CPAP) can increase dynamic…
- Trial name
- EDIN-IDIN (NCT06713486)
- Testing
- Fixed pressure obtained in the polysomnography for 28 days, Dynamic pressure in Dreamstation AVAPS-AAM PhilipsRespironic® mode
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Cystic Fibrosis, Lung Clearance Index
Exploratory Study on Link Between Dynamic Hyperinflation and Lung Clearance Index in Cystic Fibrosis
Recent improvements in cystic fibrosis management have enabled an important subset of patients to maintain normal spirometry. Nevertheless, even in these patients with normal spirometry, chest computed tomography (CT) might…
- Trial name
- ICP2DM (NCT03323983)
- Testing
- data collection
- Volunteers
- 12 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
COPD
Dynamic Hyperinflation and Tiotropium
We will detect dynamic hyperinflation (DH) in 40 COPD (chronic obstructive pulmonary disease) patients with moderately severe disease using metronome paced hyperventilation (MPH) with inspiratory capacity as the primary end…
- Trial name
- NCT00569270
- Where
- 2 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- Gelb, Arthur F., M.D.
Pulmonary Disease, Chronic Obstructive, Chronic Bronchitis
Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease Patients
The primary objective is to comparatively evaluate the isolated effects of a long-acting beta2-adrenergic (formoterol fumarate 12µg b.i.d.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Chronic Bronchitis, Pulmonary Emphysema
- Trial name
- NCT00680056
- Testing
- Formoterol plus Tiotropium
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Federal University of São Paulo
COPD, Emphysema
Tiotropium Induced Bronchodilation in Lung CT Scored Emphysema
To evaluate if tiotropium (Spiriva)induced bronchodilation of inspiratory capacity in patients with moderate to severe copd subjected to metronome paced hyperventilation induced dynamic hyperinflation is dependent upon the extent…
- Trial name
- NCT00570544
- Testing
- tiotropium
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Gelb, Arthur F., M.D.