Clinical trials: Dysarthria
Dysarthria
INcorporating VoIce AcTivated Communication Aids Into Everyday Communication
Dysarthria is a speech disorder resulting in speech that is slow, slurred and difficult to understand, limiting a person's opportunities to study, work, and develop relationships.
- Trial name
- INVITE (NCT05859438)
- Testing
- Communication aid support
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Sheffield
Hearing Loss, Sensorineural, Dysarthria
Application of Ideal Binary Masking to Disordered Speech
Dysarthria and hearing loss are communication disorders that can substantially reduce intelligibility of speech and the addition of background noise adds a further challenge.
- Trial name
- NCT05244603
- Testing
- Ideal binary mask
- Where
- United States
- Volunteers
- 435 people, healthy volunteers welcome
- Sponsor
- Utah State University
Stroke, Dysarthria
Deep Brain Stimulation + Therapy for Stroke
The purpose of this study is to evaluate the safety and potential benefits of combining deep brain stimulation (DBS) with targeted speech and swallowing rehabilitation in individuals who have experienced a stroke and have…
- Conditions
- Stroke, Dysarthria, Apraxia, Dysphagia
- Trial name
- NCT07849114
- Testing
- Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pirondini, Elvira, PhD
Parkinson's Disease
Evaluation of Intensive Language Therapy
Due to Parkinson's Disease (PD) speech and language (SL) deficits may occur. Further, the literature reports that PD patients, who have not undergone deep brain stimulation (DBS), have deficits regarding voice quality (e.g.
- Trial name
- EILT (NCT02935842)
- Testing
- Specific SL-therapy, Rhythmic Balance-Movement Training (rBMT)
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Parkinson Disease, Multiple System Atrophy
Differential Diagnosis Between Parkinson's Disease and Multiple System Atrophy Using Digital Speech Analysis - Part 2
Parkinson's disease (PD) is the second most common neurodegenerative disease. Multiple system atrophy (MSA) is a relentlessly progressing rare neurodegenerative disease of unknown etiology.
- Trial name
- Voice4PD-MSA (NCT05807373)
- Testing
- voice recordings
- Where
- 2 sites in France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Dystonia, Primary, Dysarthria
Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular
To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement…
- Conditions
- Dystonia, Primary, Dysarthria, Dysphonia, Dysphagia
- Trial name
- DOM (NCT03380676)
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Acute Stroke
The Incidence of Aphasia, Dysarthria and Dysphagia Following Stroke
The objective of the study is to estimate the incidence and recovery of aphasia, dysarthria and dysphagia in an acute setting (first week) with the NIHSS sub-item scores for language and speech and a dysphagia screening.
- Trial name
- NCT03472625
- Testing
- Screening and diagnosis of aphasia, dysarthria, dysphagia
- Where
- Belgium
- Volunteers
- 557 people
- Sponsor
- University Hospital, Ghent
Dysarthria, Stroke
Non-invasive Brain Stimulation as a Treatment for Dysarthria Post-stroke
The proposed study aimed to determine if tDCS can help post-stroke patients with dysarthria.
- Trial name
- NCT05497362
- Testing
- Real tDCS
- Where
- Hong Kong
- Volunteers
- 9 people
- Sponsor
- The University of Hong Kong
Dysarthria
Development of Dual Language (Urdu and English) Digital Software for SA, Management Of Adult Dysarthria
The research focuses on the development of a dual-language (Urdu and English) digital software designed for the self-assessment and management of adult dysarthria patients.
- Trial name
- NCT07129291
- Testing
- Experimental: Dual-Language Dysarthria Self-Assessment and Management Software (D-SAMS)
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Superior University
Tetraplegia/Tetraparesis, Quadriplegia
VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration
The VOICE Study is an early feasibility study to evaluate the initial clinical safety and efficacy of the N1 and R1 Systems device design concept in providing an ability to communicate.
- Conditions
- Tetraplegia/Tetraparesis, Quadriplegia, Cervical Spinal Cord Injury, Amyotrophic Lateral Sclerosis
- Trial name
- NCT07224256
- Testing
- N1 Implant, R1 Robot
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Neuralink Corp
Primary Progressive Aphasia, Dementia
Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia
Difficulties with speech and language are the first and most notable symptoms of primary progressive aphasia (PPA). While there is evidence that demonstrates positive effects of speech-language treatment for individuals with PPA…
- Conditions
- Primary Progressive Aphasia, Dementia, Dementia, Frontotemporal, Alzheimer Disease
- Trial name
- NCT05741853
- Testing
- Video-Implemented Script Training for Aphasia (VISTA), Lexical Retrieval Training (LRT)
- Where
- 3 sites in United States, Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stephanie Grasso
Parkinson Disease
Effect of Speech Therapy in Combination With Non-invasive Brain Stimulation on Speech of Patients With Parkinson's Disease
Up to 90% of patients with Parkinson's disease (PD) have hypokinetic dysarthria (HD) in the early phase of the illness. HD is characterized by a harsh breathy voice quality, reduced variability of pitch and loudness and imprecise…
- Trial name
- NCT06416553
- Testing
- Home-based transcranial direct current stimulation- real tDCS, Lee-Silverman voice treatment
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Masaryk University
Parkinson's Disease, Dysarthria
Improve Speech Using an In-the-ear Device in Parkinson's Disease
This project will systematically examine the therapeutic effect of altered auditory feedback provided by the in-the-ear device on the speech impairments in patients with Parkinson's disease.
- Trial name
- MJFFSpeech (NCT00488657)
- Testing
- SpeechEasy Model ITC
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Rush University Medical Center
Acquired Dysarthria (Finding)
Immediate Effects of Postural Repositioning on Voice Production Tasks in Seated Individuals With Acquired Dysarthria:
To determine the effectiveness of a single 10-min postural repositioning session on the maximum phonation duration in individuals with acquired dysarthria.
- Trial name
- NCT04520828
- Testing
- postural repositioning
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Parkinson Disease, Dysarthria
Subthalamic Nucleus Deep Brain Stimulation in Speech Study
Parkinson's disease (PD) patients treated with deep brain stimulation (DBS) of the subthalamic nucleus (STN) have unpredictable and varied speech outcomes after this treatment.
- Trial name
- SiSS (NCT05493670)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Jeremy Greenlee
Cerebral Palsy, Dysarthria
Speech Motor Treatment in Cerebral Palsy
Cerebral palsy (CP) is the most frequent cause of motor disability worldwide, with a prevalence of 2-2.5 per 1000 live births. Children with CP may experience a variety of difficulties with communication including speech.
- Trial name
- NCT04189159
- Testing
- PROMPT
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS Fondazione Stella Maris
Anarthria, Dysarthria
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
The purpose of this study is to obtain preliminary device safety information and demonstrate proof of principle (feasibility) of the ability of people with tetraplegia to control a computer cursor and other assistive devices with…
- Conditions
- Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries
- Trial name
- BG-Speech-01 (NCT05724173)
- Testing
- BrainGate Neural Interface System
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Leigh R. Hochberg, MD, PhD.
Hypokinetic Dysathria
The Effect of LSVT LOUD for Mandarin-speaking Individuals With Hypokinetic Dysarthria Due to Parkinson's Disease
A handful of studies have examined the effects of the Lee Silverman Voice Treatment (LSVT) LOUD on hypokinetic dysarthria in English speakers with Parkinson's disease (PD).
- Trial name
- NCT02506205
- Testing
- Lee Silverman Voice Treatment (SVLT) LOUD
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Parkinson's Disease, Deep Brain Stimulation
Can Subthalamic Stimulation Using Directional Electrodes Improve Postoperative Management in Parkinson's Disease
The primary objective of the study is to determine if subthalamic nucleus (STN) deep brain stimulation (DBS) using the Vercise directional leads improves neuropsychiatric state and neuropsychiatric fluctuations 12 months after…
- Trial name
- Steeropt (NCT04578678)
- Testing
- Steering
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 105 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Parkinson Disease, Dysarthria, Hypokinetic
A Multidimensional Study on Articulation Deficits in Parkinsons Disease
Articulatory deficits are present in most speakers with dysarthria, which negatively impacts their speech intelligibility, yet little is known about the relationship between articulatory movement and speech intelligibility.
- Trial name
- NCT05754086
- Testing
- Clear Speech, Less Clear Speech
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Florida State University