Clinical trials: Dysentery
Shigella, Diarrhea
First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in Healthy Young Adults
Phase 1 trial to evaluate the Safety and Immunogenicity of Inventprise's (IVT) Shigella-04 in Healthy Young Adults
- Trial name
- NCT07205926
- Testing
- IVT Shigella-04
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inventprise Inc.
Dysentery, Shigella
Safety and Efficacy Study of WRSS1, a Shigella Sonnei Vaccine Candidate
This study is an inpatient trial to determine the safety, immunogenicity and efficacy of the WRSS1 candidate vaccine in healthy Thai adult volunteers.
- Conditions
- Dysentery, Shigella, Diarrhea
- Trial name
- NCT01080716
- Testing
- Part 1/Arm 1 of Study: WRSS1 vaccine, Part 2/Arm 1 of Study: S. sonnei 53G, Part 2/Arm 2 of Study: S. sonnei 53G
- Where
- Thailand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Testing Effect of Intervention
Zinc Supplementation in Shigella Patients
Shigellosis is a major cause of morbidity and mortality in young children in Bangladesh and other developing countries. Further, the increasing emergence of resistance to a wide range of antibiotics is of great concern.
- Trial name
- NCT00321126
- Testing
- Children in the zinc group received 20 mg of elemental zinc as acetate per day in a twice-daily dose for two weeks.
- Volunteers
- 56 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Diarrhea, Shigella
Multidrug Resistant Shigella Infection in Bangladesh
The purpose of this project is to systematically collect clinical and nutritional outcomes information on patients treated for Shigella infection so that physicians and clinical laboratories can better define which Shigella…
- Trial name
- NCT03778125
- Where
- Bangladesh
- Volunteers
- 2,000 people
- Sponsor
- University of Virginia
Diarrhea, Dysentery
New Hypo-Osmolar ORS (Recommended by WHO) for Routine Use in the Diarrhea Management- Surveillance Study for Adverse Effects
For more than 25 years WHO and UNICEF have recommended a single formulation of glucose-based Oral Rehydration Salts (ORS) to prevent or treat dehydration from diarrhoea irrespective of the cause or age group affected.
- Trial name
- NCT00490932
- Testing
- Hypo-osmolar ORS
- Where
- India
- Volunteers
- 27,966 people
- Sponsor
- Society for Applied Studies
Diarrhoea;Infectious;Presumed, Diarrhea, Infantile
Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa
This project is a community-based randomized controlled trial designed to test the effectiveness of two point-of-use water treatment technologies to improve clean drinking water access, reduce enteropathogen burden, and improve…
- Conditions
- Diarrhoea;Infectious;Presumed, Diarrhea, Infantile, Diarrhea Tropical, Environmental Exposure
- Trial name
- NCT03012048
- Testing
- Silver-impregnated ceramic tablet, Silver-impregnated ceramic water filter, Safe-storage water container
- Where
- South Africa
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- University of Virginia