Clinical trials: Dysglycemia
Dysglycemia, Cognitive Deficit
Long-acting Exenatide and Cognitive Decline in Dysglycemic Patients
The overall objective of the study is to assess the potential effects of the long-acting GLP-1 analogue exenatide in preventing/slowing the progression of cognitive dysfunction and related biomarkers in dysglycemic/prediabetic…
- Trial name
- DRINN (NCT02847403)
- Testing
- Exenatide
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Metabolic Syndrome
Effect of Vitamin D on Metabolic Parameters in Patients With the Metabolic Syndrome
In recent years emphasis has been given to investigate the role of vitamin D in areas beyond bone metabolism and maintenance of calcium homeostasis.
- Trial name
- NCT01237769
- Testing
- Vitamin D3, Lifestyle advice
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Ioannina
Dysglycaemia
Achieving Normal Glucose In Hospital Settings
The main objective of this study is to evaluate the efficacy and safety of 24 hours of closed-loop glucose control compared with standard diabetes treatment, in patients with type 2 diabetes treated by non-insulin…
- Trial name
- Angie01 (NCT01359241)
- Testing
- closed-loop insulin delivery, Usual diabetes treatment regimen
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- University of Cambridge
Diabetes, Obesity
Polish Registry of Diabetes (PolReD)
The aim of this project is to create a registry of diabetic patients, containing a detailed clinical profile of each patient, along with omics data, which will be analyzed using artificial intelligence algorithms, and their…
- Conditions
- Diabetes, Obesity, PreDiabetes, Dysglycemia
- Trial name
- PolReD (NCT04657367)
- Testing
- Observational study - registry
- Where
- Poland
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Dysglycemia
Berberine, Curcumin, Inositol, Banaba and Chromium Picolinate in Patients With Fasting Dysglycemia
Dysglycemia is an important pre-risk condition which can potentially lead to diabetes if not adequately treated. The variation of glycemic balance can lead to cardiovascular disorders.
- Trial name
- NCT04107987
- Testing
- Reglicem
- Where
- Italy
- Volunteers
- 148 people
- Sponsor
- University of Pavia
Gestatiaonl Diabetes Mellitus, GDM
Study to Prevent Dysglycemia in Women With GDM
Women with a history of gestational diabetes mellitus (GDM) have a 7-fold increased risk of type 2 diabetes (T2D), with the risk at its highest during the 3-6 years postpartum.
- Trial name
- NCT07269405
- Testing
- Intervention, Conventional care
- Where
- Hong Kong
- Volunteers
- 800 people
- Sponsor
- Chinese University of Hong Kong
COVID-19, Dysglycemia
Can Intensive Insulin Therapy Improve Outcomes of COVID-19 Patients
Evaluation of the reciprocal relation between hyperglycemia/diabetes mellitus (HG/DM) and COVID-19 disease and the effect of mode of insulin therapy; intensive (IIT) or conventional (CIT) on patients' outcomes All patients…
- Trial name
- NCT05441631
- Testing
- Insulin, Subcutaneous Insulin
- Where
- Egypt
- Volunteers
- 436 people
- Sponsor
- Benha University
Gestational Diabetes
Continuous Glucose Monitoring to Detect Postpartum Dysglycemia in Patients With Gestational Diabetes
The aim of this study is to determine the ability of postpartum continuous glucose monitoring (CGM) for subjects with gestational diabetes (GDM) to predict dysglycemia on 4-12 week postpartum oral glucose tolerance test (OGTT).
- Trial name
- NCT07034261
- Testing
- Blinded Continuous Glucose Monitoring Device
- Volunteers
- 50 people
- Sponsor
- University of Chicago
Gestational Diabetes Mellitus (GDM)
Screening for Dysglycemia During Postpartum Period in Women With GDM
Gestational diabetes mellitus (GDM) is one of the most common clinical conditions in pregnancy, with an increasing incidence due to the rise in overweight women and the postponement of motherhood.
- Trial name
- NCT07489456
- Testing
- Whatsapp message
- Where
- Brazil
- Volunteers
- 182 people
- Sponsor
- University of Sao Paulo General Hospital
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Cystic Fibrosis
Treatment of Dysglycemia Using Sitagliptin in Adolescents With Cystic Fibrosis
This pilot study will be conducted in adolescents with cystic fibrosis (CF) without diabetes but with abnormal glucose tolerance, and will assess the effects of sitagliptin on glucose regulation.
- Trial name
- NCT01721382
- Testing
- Sitagliptin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Nemours Children's Clinic
PreDiabetes, Diabetes Mellitus
Dried Fruit and Postprandial Glycemia Trial
Dried fruits show promising potential for the management of blood glucose. Previous trials have reported beneficial effects of raisins on post-prandial glucose and insulin responses in healthy individuals when compared with white…
- Conditions
- PreDiabetes, Diabetes Mellitus, Dysglycemia
- Trial name
- NCT02960373
- Testing
- White Bread (Control), Dried Fruit - Glycemic Index, Catalytic Fructose Dose Effect
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hemodialysis, Diabete Mellitus
Continuous Glucose Monitoring in Dialysis Patients to Overcome Dysglycemia Trial
This randomized controlled trial will investigate whether use of continuous glucose monitoring (CGM) vs. usual care with self-monitored blood glucose 1) enhances glycemic control, 2) reduces hypoglycemia risk, and 3) improves…
- Conditions
- Hemodialysis, Diabete Mellitus, Continuous Glucose Monitoring
- Trial name
- CONDOR (NCT05509881)
- Testing
- Continuous glucose monitoring (CGM), Usual care (Self-monitored blood glucose)
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of California, Irvine
Diabetes Mellitus, Dysglycemia
The Effect of Continuous Glucose Monitoring in Surgical Patients With Diabetes.
The goal of this randomised controlled trial to investigate the effect of continuous glucose monitoring (CGM) compared to standard point-of-care (POC) blood glucose measurements in surgical patients with diabetes in patients.
- Conditions
- Diabetes Mellitus, Dysglycemia, Perioperative Complication
- Trial name
- WARD-glucose (NCT06314061)
- Testing
- Dexcom G7 Continuous Glucose Monitoring (CGM) System (G7)
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Christian S. Meyhoff
Obesity, Dysglycemia
Metabolic Effects of Betaine Supplementation
Betaine is important in cellular metabolic pathways. Few epidemiologic studies link betaine levels to diabetes and cardiovascular disease. Small human studies suggest benefit for non-alcoholic liver disease.
- Trial name
- NCT01950039
- Testing
- Betaine
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Joslin Diabetes Center
Dysglycemia, Dyslipidemia
Micronutrients and Health in Adult Chinese
Adult subjects were recruited from a health examination center. Their fasting blood samples were collected for laboratory analyses of multiple measures including mineral, glucose, lipids, etc.
- Trial name
- NCT04004143
- Testing
- No intervention
- Volunteers
- 1,520 people, healthy volunteers welcome
- Sponsor
- Shenzhen Center for Chronic Disease Control
Prediabetic State, Diabetes type2
Effect of Totum-63 on Glucose and Lipid Homeostasis in Subjects With Dysglycemia (REVERSE-IT)
This clinical study aims to assess the efficacy of TOTUM-63, a mix of 5 plant extracts, consumed at the daily regimen of three times per day on glucose and lipid homeostasis in dysglycemic subjects.
- Conditions
- Prediabetic State, Diabetes type2, Dysglycemia
- Trial name
- REVERSE-IT (NCT04423302)
- Testing
- TOTUM-63 3 intakes per day, TOTUM-63 2 intakes per day
- Where
- 52 sites in Bulgaria, France and 5 more
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Valbiotis
Stage 1 Diabetes Mellitus, Type 1
Fr1da Insulin Intervention
Type 1 diabetes (T1D) results from an autoimmune destruction of the insulin-producing beta cells. The process of autoimmune destruction is identified by circulating islet autoantibodies to beta cell antigens, and is mediated by a…
- Trial name
- NCT02620072
- Testing
- Oral Insulin
- Where
- Germany
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Gestational Diabetes Mellitus, Hypertension in Pregnancy
Supporting Transitions to Primary Care Among Under-resourced, Postpartum Women (STEP-UP)
STEP-UP will promote linkage to primary care and ongoing chronic disease evaluation for postpartum women with prior gestational diabetes mellitus (GDM) and/or hypertensive disorders of pregnancy (HDP).
- Conditions
- Gestational Diabetes Mellitus, Hypertension in Pregnancy, Dysglycemia
- Trial name
- NCT05852054
- Testing
- OB Provider Clinical Decision Support (CDS), Patient Education (OB Visit), Text messaging
- Where
- 2 sites in United States
- Volunteers
- 2,306 people
- Sponsor
- Northwestern University
Healthy, Overweight and Obesity
Strategies To OPpose Sugars With Non-nutritive Sweeteners Or Water (STOP Sugars NOW) Trial
Health authorities recommend a reduction in added sugars from sugar-sweetened beverages (SSBs) due to risk of obesity and diabetes. As a sugar-reduction strategy, finding the ideal SSB replacement is of the utmost importance.
- Conditions
- Healthy, Overweight and Obesity, Metabolic Syndrome, PreDiabetes
- Trial name
- NCT03543644
- Testing
- Sugar-sweetened beverage (SSB), Non-nutritive sweetened beverages (NSB), Water
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Toronto