Clinical trials: Dyskinesia
Restlessness, Pain
Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Dexmedetomidine is a highly selective α2 adrenoreceptor agonist approved by the US FDA for short-term postoperative sedation and analgesia.It can also reduce the stress response without respiratory depression.
- Trial name
- NCT01517932
- Testing
- dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Fang Luo
Scapular Dyskinesis, Sedentary Behavior
Compare the Scapular Muscular Endurance, Stabilization and Dyskinesis Parameters of Sedentary Individuals
The aim of this study was to compare the parameters of scapular muscular endurance, scapular stabilization, scapular dyskinesia, upper extremity functional status and postural alignment of adult women aged between 40-65 years old…
- Trial name
- NCT04296539
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Aging Problems, Coordination Impairment
Effects of Jaques-Dalcroze Eurhythmics Program on Postural Stability in Elderly Women.
This study investigated the effect of exercise using the Emil Jaques-Dalcroze's method on the postural stability of women over 65 years of age. The study model was based on a randomized controlled trial - parallel group design.
- Trial name
- NCT05015777
- Testing
- Emil Jaques-Dalcroze's Eurhythimcs Exercise Program
- Where
- Poland
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Kidney Transplant Recipients, Old Age
Neurocognitive Function Changes With Extended-Release Tacrolimus Among Older Kidney Transplant Recipients
The objective of this randomized controlled study is to assess the neurocognitive outcomes between individuals using immediate-release (IR) tacrolimus (Prograf®) and those who were converted to extended-release tacrolimus…
- Trial name
- Neuro-KTR (NCT06751992)
- Testing
- Conversion to extended-release tacrolimus, Maintenance of immediate-release tacrolimus
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Massachusetts General Hospital
Delirium, Agitation
Randomized Controlled Trial of Dexmedetomidine for the Treatment of Intensive Care Unit (ICU) Delirium
The purpose of the research is to see if dexmedetomidine (a drug that has a calming effect - a sedative) is effective for the treatment of acute delirium
- Trial name
- NCT00351299
- Testing
- Dexmedetomidine, Standard of Care
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Brigham and Women's Hospital
Oral Cancer
Morphological Changes of Upper Trapezius Muscle After Physotherapy in Oral Cancer
The study aims to evaluate the morphological changes of upper trapezius muscle, using B-mode ultrasonography, in patients with oral cancer undergone neck dissection and physiotherapy.
- Trial name
- NCT07166575
- Testing
- B-mode ultrasonography
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
SPINOCEREBELLAR ATAXIA 2
Safety and Tolerability of Lithium in Spinocerebellar Ataxia 2 (SCA2)
The purpose of this study is to determine safety and tolerability of the treatment with lithium in Spinocerebellar Ataxia 2. Moreover, clinical symptoms, neuronal loss, quality of life and depressive symptoms, will be considered…
- Trial name
- LISCA2 (NCT00998634)
- Testing
- LITHIUM CARBONATE
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Federico II University
Tourette Syndrome, Tic Disorders
Cognitive Behavior Therapy and Habit Reversal Training for the Treatment of Chronic Tic Disorders in Children
This study will determine the effectiveness of cognitive behavior therapy (CBT) with habit reversal training (HRT) in treating chronic tic disorders (CTDs) in children and adolescents.
- Trial name
- CBIT (NCT00218777)
- Testing
- Comprehensive Behavioral Intervention for Tics
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Tourette Association of America
Rett Syndrome
Treatment of Mitochondrial Dysfunction in Rett Syndrome With Triheptanoin
The aim of this study is to evaluate the safety and tolerability of triheptanoin in participants with Rett syndrome using laboratory values, electrocardiogram, rate of adverse events (AE), and physical exam.This study also seeks…
- Trial name
- NCT02696044
- Testing
- triheptanoin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Center for Rare Neurological Diseases, Norcross, GA
Huntington's Disease
HD-Charge: Indirect and Out-of-Pocket Costs of Huntington's Disease in the United States
Huntington's disease (HD) is a rare, inherited and progressive neurodegenerative disorder for which hallmark symptoms include movement disorders, loss of cognitive faculties and psychiatric disturbances.
- Trial name
- NCT03628235
- Testing
- Online survey
- Where
- 11 sites in United States
- Volunteers
- 233 people
- Sponsor
- CHDI Foundation, Inc.
Huntington Disease
Study to Evaluate the Pharmacodynamics, Safety and Efficacy of SKY-0515 in Participants With Huntington's Disease
The goal of this clinical trial is to test if the drug SKY-0515, an oral medication, can lower harmful proteins linked to Huntington's Disease (HD) and improve the symptoms of participants with HD.
- Trial name
- FALCON-HD (NCT07378644)
- Testing
- SKY-0515
- Where
- 31 sites in United States, Argentina and 8 more
- Volunteers
- 400 people
- Sponsor
- Skyhawk Therapeutics, Inc.
Huntington Disease
Longitudinal Endpoint Assessment of Disease Burden in HD
LEAD-HD is intended to collect and analyze self-reported health information from individuals with Huntington Disease (HD) or prodromal HD participating in a 24-month longitudinal natural history study using remote technologies.
- Trial name
- LEAD-HD (NCT06475898)
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Huntington Study Group
Focal Hand Dystonia, Musician's Dystonia
Somatosensory Processing in Focal Hand Dystonia
Patients with focal dystonia experience uncontrollable movements of the hand during certain types of skilled movements. Though the origin of the disorder is not fully understood, it is thought that brain areas involved in moving…
- Conditions
- Focal Hand Dystonia, Musician's Dystonia, Writer's Cramp, Dystonic Cramp
- Trial name
- NCT00579033
- Testing
- Tactile training + rTMS
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Dementia, Alzheimer Disease
The Healthy Patterns Sleep Study
The Healthy Patterns Study intervention is a home-based activity intervention designed to improve symptoms of circadian rhythm disorders (CRD) and quality of life (QOL) in home-dwelling persons with dementia.
- Conditions
- Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder
- Trial name
- NCT03682185
- Testing
- Attention-Control Condition, Timed Activity Intervention
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Primary Ciliary Dyskinesia (PCD), Cystic Fibrosis (CF)
Clean Air for Rare MUcociliary Clearance dIsorders
The goal of this clinical trial is to learn whether using a high efficiency particulate air (HEPA) air purifier can improve respiratory health in children and adults with Cystic Fibrosis (CF) or Primary Ciliary Dyskinesia (PCD).
- Trial name
- CARMUCI (NCT07417267)
- Testing
- Intervention configuration - air purifiers equipped with HEPA and three other filters for efficient particle filtration
- Where
- Cyprus
- Volunteers
- 62 people
- Sponsor
- University of Cyprus
Parkinson's Disease, Levodopa Induced Dyskinesia (LID)
Efficacy and Safety of JM-010 in PD With Levodopa-Induced Dyskinesia
The purpose of a randomized, double-blind, placebo-controlled, 2-way crossover study is to evaluate the efficacy, safety/tolerability and pharmacokinetics of JM-010 for the treatment of subjects with Parkinson's Disease (PD) with…
- Trial name
- LID (NCT02439203)
- Testing
- JM-010
- Where
- South Africa
- Volunteers
- 30 people
- Sponsor
- Bukwang Pharmaceutical
Sphincter of Oddi Dysfunction
Evaluating Predictors & Interventions in Sphincter of Oddi Dysfunction
The Evaluating Predictors \& Interventions in Sphincter of Oddi Dysfunction(SOD) study (EPISOD) is a randomized sham-controlled study of biliary and pancreatic sphincterotomy as treatment for patients with pain after…
- Trial name
- EPISOD (NCT00688662)
- Testing
- ERCP with sphincterotomy, ERCP without sphincterotomy
- Where
- 7 sites in United States
- Volunteers
- 214 people
- Sponsor
- Medical University of South Carolina
Cervical Dystonia, Primary
The Effects of Waning of Botulinum Toxin in the Treatment of Cervical Dystonia
The main treatment for cervical dystonia is botulinum toxin injections. However, some patients receiving this treatment after many years tend to experience short duration of benefit.
- Trial name
- NCT06886750
- Testing
- Botulinum toxin type A injection
- Volunteers
- 45 people
- Sponsor
- Western University, Canada
Primary Ciliary Dyskinesia
Clearing Lungs With ENaC Inhibition in Primary Ciliary Dyskinesia
To evaluate the safety and efficacy of treatment with VX-371 with and without ivacaftor, and the effect of VX-371 with and without ivacaftor on quality of life (QOL) in subjects with primary ciliary dyskinesia (PCD).
- Trial name
- CLEAN-PCD (NCT02871778)
- Testing
- VX-371, Hypertonic Saline, VX-371 + HS
- Where
- 34 sites in United States, Canada and 6 more
- Volunteers
- 123 people
- Sponsor
- Parion Sciences
Scapular Dyskinesis, Shockwave Therapy
Routine Rehabilitation Versus Shock Wave Therapy for Scapular Dyskinesis
It has been proposed that altered scapular muscle function can contribute to alterations in shoulder kinematics, which often lead to SD and are frequently associated with other shoulder pathologies.
- Trial name
- NCT07633340
- Testing
- Radial extracorporeal shock wave therapy (active comparator)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.