Clinical trials: Dyskinesia
Muscle Dystonia
Neuromuscular Electrical Stimulation for Jaw-closing Dystonia
6 patients with jaw-closing dystonia will be treated with neuromuscular electrical stimulation over 8 weeks. The distance the mouth can be opened voluntarily and the oro-mandibular dystonia questionnaire (OMDQ-25) will be…
- Trial name
- NCT03889704
- Testing
- Omnistim® FX²
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Edward Burton
Dementia
Study of Mirtazapine for Agitation in Dementia
This clinical trial evaluates whether Mirtazapine is more effective than placebo in treating agitation in people with dementia. The trial will assess the safety, clinical and cost effectiveness of the treatment.
- Trial name
- SYMBAD (NCT03031184)
- Testing
- Mirtazapine
- Where
- United Kingdom
- Volunteers
- 207 people
- Sponsor
- University of Sussex
Ataxia Telangiectasia
Immunogenicity of Pneumococcal Vaccines in Ataxia-telangiectasia Patients
Ataxia-telangiectasia (AT) is a rare genetic disorder characterized by gait disorders, neuromotor dysfunction, eye abnormalities and immune deficiency.
- Trial name
- NCT01075438
- Testing
- Prevenar® (7-valent pneumococcal conjugate vaccine), Pneumovax® (pneumococcal polysaccharide vaccine)
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Cerebral Palsy.
Exploring Hypertonia in Children With Cerebral Palsy
Abnormal limb and trunk movements are seen in many children with cerebral palsy. Recognizing the difference between types of these movements is not well understood.
- Trial name
- HypE-CP (NCT01744158)
- Testing
- No intervention applicable
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Women's and Children's Hospital, Australia
Agitation
Acute Agitation in Emergency Psychiatry
The purpose of the study is to improve the pharmacological treatment of psychiatric patients with acute agitation.
- Trial name
- NCT06752616
- Testing
- Sublingual Dexmedetomidine, Buccal midazolam, Oral lorazepam
- Where
- Denmark
- Volunteers
- 132 people
- Sponsor
- Lone Baandrup
Spinocerebellar Ataxia Type 10
Genetic Mechanism of Conserved Ancestral Haplotype in SCA10
Spinocerebellar ataxia type 10 (SCA10) is a hereditary ataxia whose ancestral mutation occurred in East Asia. The mutation is likely to have migrated during peopling of American continents from East Asia.
- Trial name
- CAHSCA10 (NCT04495426)
- Testing
- Non-interventional study
- Where
- 3 sites in United States, Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Acoustic Stimulation, Parkinson Disease
Rhythmic Auditory Stimulation on Upper-limb Movements in PD Patients
The goal of this clinical trial is to examine effects of training involving rhythmic auditory stimulation (RAS) on upper-limb movements and functions in patients with Parkinson's disease (PD).
- Conditions
- Acoustic Stimulation, Parkinson Disease, Movement, Abnormal, Bradykinesia
- Trial name
- NCT05637593
- Testing
- Upper-limb movement training with the aid of RAS, Upper-limb movement training without the aid of RAS
- Where
- China
- Volunteers
- 38 people
- Sponsor
- The Hong Kong Polytechnic University
Huntington's Disease
Follow-up Measurement of Brain PDE10A Enzyme Levels in Huntington´s Disease Gene Expansion Carriers
The aim of this study is to measure longitudinally the availability of the PDE10A enzyme in HDGECs using the radioligand [18F]MNI-659.
- Trial name
- LONGPDE10 (NCT02956148)
- Testing
- Radioligand [18F]MNI-659
- Where
- 7 sites in Denmark, Netherlands and 2 more
- Volunteers
- 45 people
- Sponsor
- CHDI Foundation, Inc.
Cystic Fibrosis, Primary Ciliary Dyskinesia
Inflammatory and Microbiologic Markers in Sputum: Comparing Cystic Fibrosis With Primary Ciliary Dyskinesia
The objective of this study is to compare the lower airways inflammatory response to infection/pulmonary exacerbation among children known to have Primary Ciliary Dyskinesia (PCD) with children known to have Cystic Fibrosis (CF)…
- Trial name
- NCT01155115
- Testing
- Sputum Collection, Pulmonary Function Testing, Exhaled Nitric Oxide
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- The Hospital for Sick Children
Parkinson Disease
Strategy for Daily Activity Improvement in Patients With Parkinson's Disease
The symptoms and signs of patients with Parkinson's disease (PD) include bradykinesia, rigidity, tremor and poor sensory integration, which result in mobility disability.
- Trial name
- Parkinson (NCT03972241)
- Testing
- foot insole
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kwan-Hwa Lin
Tremor, Limb
The Trans-cutaneous Effects on Physiological Tremor Entertainment During tACS
Transcranial alternating current stimulation (tACS) is a noninvasive neuromodulation method that works by passing alternating electric current between electrodes where at least one of them is attached to the head.
- Trial name
- NCT04065022
- Testing
- tACS at tremor frequency
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- KU Leuven
Huntington Disease
Open-label Extension Study of Pridopidine (ACR16) in the Symptomatic Treatment of Huntington Disease
Huntington disease (HD) is a hereditary neurodegenerative disorder causing impairment in movement, behavioral dysfunction and dementia.
- Trial name
- OPEN-HART (NCT01306929)
- Testing
- pridopidine
- Volunteers
- 134 people
- Sponsor
- Prilenia
Psychomotor Agitation, Psychiatric Disorder
Randomised Trial Ketiapine Olanzapine Fast Sedation Agitated Patients Emergency Ward
comparison of intramuscular olanzapine and ketamine efficacy as first medication for fast sedation of patients with agitation and aggressive behavior.
- Conditions
- Psychomotor Agitation, Psychiatric Disorder, Emergency Psychiatric, Tranquilizers
- Trial name
- IM-OK-FAST (NCT03216941)
- Testing
- Ketamine
- Where
- Argentina
- Volunteers
- 500 people
- Sponsor
- Universidad Nacional de Rosario
Multiple Sclerosis
Bilateral Anodal Cerebellar tDCS for Multidomain Dysfunctions in Patients With Multiple Sclerosis
The goal of this clinical trial is to learn if brain stimulation can improve movement and daily function in people with multiple sclerosis (MS).
- Trial name
- CerebellertDCS (NCT07555379)
- Testing
- Bilateral Cerebellar Transcranial Direct Current Stimulation (ctDCS)
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- University of Sharjah
Essential Tremor, Parkinson Disease
Physiology, Imaging and Modeling of Essential Tremor
This project aims to investigate novel ways to deliver brain stimulation to Essential Tremor (ET) patients by introducing software changes to their existing devices.
- Conditions
- Essential Tremor, Parkinson Disease, Dystonia
- Trial name
- NCT03811405
- Testing
- Active biphasic pulse stimulation---Home Settings, Active biphasic pulse stimulation---VIN Biphasic, Active biphasic pulse stimulation---Stimulator Off
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Essential Tremor, Dystonia
The Effect of Alcohol on Common Tremor Syndromes
The aim of this interventional study is to compare the response to alcohol in patients with essential tremor (ET), essential tremor plus (ETplus), dystonic tremor (DT), tremor associated with dystonia (TaD) and tremor in…
- Conditions
- Essential Tremor, Dystonia, Parkinson Disease
- Trial name
- NCT06403280
- Testing
- Alcoholic drink
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Medical University of Graz
Huntington Disease
31P-MRS and Huntington Disease
The purpose of this study is to identify and quantify a brain energy deficit in Huntington patients, using 31P-RMN spectroscopy.
- Trial name
- PRO-MH (NCT01359774)
- Testing
- 31P-MR spectroscopy, 31P-RMN spectroscopy
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Huntington Disease
Dosimetry of [11C]CHDI-180R and [11C]CHDI-626.
A better understanding of the HD pathogenesis mechanisms may lead to a better understanding of disease pathology, progression and development of targeted therapies.
- Trial name
- NCT05224115
- Testing
- [11C]CHDI-00485180-R, [11C]CHDI-00485626
- Where
- Belgium
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Parkinson's Disease
Long-Term Effects of Amantadine in Parkinsonian (AMANDYSK)
This is a French national trial, conducted using a double-blind, placebo-controlled, randomised design involving 7 centers and 80 patients of both sexes.
- Trial name
- AMANDYSK (NCT00632762)
- Testing
- mantadix
- Where
- 5 sites in France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Toulouse
Cervical Spondylosis
Recovery Profiles After c Spine Surgery: With or Without Dexmedetomidine as an Anesthetic Adjuvant
The purpose of this study is to determine the recovery profiles after general anesthesia in patient undergoing anterior cervical spine surgery.
- Trial name
- NCT02819089
- Testing
- Dexmedetomidine, NSS
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.