Clinical trials: Dyspepsia
Postprandial Distress Syndrome, Functional Dyspepsia
Postprandial Distress Itopride Cohort Trial
Functional Dyspepsia (FD) is a common gastrointestinal disorder affecting about 7.2% of the population, characterized by gastroduodenal symptoms without an identifiable organic cause.
- Conditions
- Postprandial Distress Syndrome, Functional Dyspepsia, Epigastric Pain Syndrome
- Trial name
- PASSPORT (NCT07165301)
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Functional Dyspepsia, Self-help Mobile Cognitive Behavioral Therapy
Effects of Cognitive Behavioral Therapy Through a Mobile App on Patients With Refractory Functional Dyspepsia
Functional dyspepsia (FD) is a common gastrointestinal disease, which is associated with decreased life quality and increased medical cost.
- Conditions
- Functional Dyspepsia, Self-help Mobile Cognitive Behavioral Therapy, Antipsychotic Drug
- Trial name
- NCT06756139
- Testing
- cognitive behavioural therapy mobile application, Flupentixol and Melitracen Tablets
- Where
- 7 sites in China
- Volunteers
- 88 people
- Sponsor
- Air Force Military Medical University, China
Gastritis, Peptic Ulcer
Helicobacter Pylori Eradication With Berberine Quadruple Therapy Versus Clarithromycin Quadruple Therapy
This study aims at evaluating efficacy and safety of berberine-containing quadruple therapy(berberine, lansoprazole, bismuth and amoxicillin) versus clarithromycin-containing quadruple therapy (clarithromycin,lansoprazole…
- Conditions
- Gastritis, Peptic Ulcer, Dyspepsia
- Trial name
- NCT02633930
- Testing
- Berberine, clarithromycin, Bismuth
- Where
- 2 sites in China
- Volunteers
- 566 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Dyspepsia
The Role of Narrow-Band Imaging Endoscopy in Diagnosing Gastric Intestinal Metaplasia
The purpose of this study is to determine if endoscope with NBI(narrow banding imaging)can detect intestinal metaplasia( consider pre malignant condition) and use a targeting biopsy in case of suspected intestinal metaplasia
- Trial name
- NCT00673699
- Testing
- Gastric mucosal biopsy
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Hillel Yaffe Medical Center
Dyspepsia
The Effect of Rikkunshito on Gastric Accommodation and Nutrient Volume Tolerance in Functional Dyspepsia
Functional dyspepsia (FD) is a common chronic gastrointestinal (GI) disorder. Rikkunshito, a traditional Japanese Kampo medicine, has shown efficacy in improving FD symptoms in controlled trials in Japan.
- Trial name
- NCT03856294
- Testing
- Rikkunshito
- Where
- Belgium
- Volunteers
- 34 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Helicobacter Gastritis, Dyspepsia
Activation and Recruitment of GIL During Hp Infection
Helicobacter pylori is a major human pathogen that infects over half of the world population. Infection initiates a series of changes in the gastric mucosa, beginning with gastritis and leading in some patients to peptic ulcer…
- Trial name
- NCT00275886
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Functional Gastrointestinal Disorders
The Association of Clinical Symptom Clusters With Underlying Mechanisms in Functional Gastrointestinal Disorders
Functional gastrointestinal disorders (FGID) are amongst the most common causes of abdominal pain and dysfunction seen in clinical practice, affecting between 10 to 15% of most populations (1).
- Trial name
- NCT04331223
- Testing
- Observation
- Where
- Switzerland
- Volunteers
- 5,000 people
- Sponsor
- Brain-Gut Research Group
Gastroparesis, Functional Dyspepsia
Transauricular Vagal Nerve Stimulation; Functional Dyspepsia and Gastroparesis
The goal of this study is to establish parameters of gastric myoelectrical activity and heart rate variability in healthy human subjects and compare and contrast them to those with gastroparesis and functional dyspepsia, at…
- Conditions
- Gastroparesis, Functional Dyspepsia, Healthy, Digestive System Disease
- Trial name
- AVNS (NCT05405842)
- Testing
- Transauricular Vagal Nerve Stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Helicobacter Pylori Infection
Efficacy and Safety of Lacidofil® STRONG as an Adjuvant for Helicobacter Pylori Treatment in Non-ulcer Dyspepsia
Treatment for H. pylori eradication includes antibiotics. The treatment has decreased its efficiency (lower capability to eradicate the infection) due to increasing antibiotic resistance in the population.
- Trial name
- NCT04473079
- Testing
- Lacidofil
- Where
- Thailand
- Volunteers
- 90 people
- Sponsor
- Lallemand Health Solutions
Helicobacter Pylori-positive With Functional Dyspepsia
Effect of H. Pylori Eradication on Alleviating Symptoms in Functional Dyspepsia Patients
In patients with Helicobacter pylori-positive functional dyspepsia, long-term follow-up for 6 months after standard triple therapy first-line eradication treatment, the rate of symptom disappearance and degree of improvement of…
- Trial name
- NCT05786807
- Testing
- K-CAB
- Where
- South Korea
- Volunteers
- 315 people
- Sponsor
- Wonkwang University Hospital
Functional Dyspepsia
Transcutaneous Auricular Vagus Nerve Stimulation Treatment on Functional Dyspepsia
Objective: To observe the effect of the treatment of transcutaneous auricular vagus nerve stimulation (taVNS) for the functional dyspepsia (FD). Methods: We accrued 94 patients at Beijing TongRen Hospital.
- Trial name
- NCT04706871
- Testing
- taVNS, tnVNS
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Tongren Hospital
Functional Dyspepsia
Treatment of Functional Dyspepsia With Acupuncture
Functional dyspepsia (FD) is one of the most common chronic gastrointestinal disorders affecting humans. Existing therapies for FD are still far from satisfactory and new therapies are constantly being sought.
- Trial name
- NCT00786214
- Testing
- Acupuncture
- Where
- Singapore
- Volunteers
- 42 people
- Sponsor
- National University Hospital, Singapore
Dyspepsia
Low-value Chronic Prescription of Acid Reducing Medication Among Dutch General Practitioners
Dyspepsia is a commonly encountered clinical condition in Dutch general practice, which is often treated through the prescription of acid-reducing medication (ARM).
- Trial name
- NCT06108817
- Testing
- Information material, No Intervention
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Dyspepsia
Efficacy of Bromopride and Simethicone Versus Bromopride in Functional Dyspepsia
Multi-center, randomized, superiority, double blind clinical trial to asses the efficacy of fixed-dose combination of bromopride and simethicone versus isolated bromopride on research participants diagnosed with functional…
- Trial name
- NCT02604576
- Testing
- FDC Bromopride 10 mg and Simethicone 80 mg, Bromopride 10 mg
- Where
- 10 sites in Brazil
- Volunteers
- 339 people
- Sponsor
- EMS
Functional Dyspepsia
Effect of Amitriptyline and Trifluoperazine on Patients With Functional Dyspepsia
The goal of this clinical trial is to assess and compare the effect of amitriptyline and trifluoperazine in improving dyspeptic symptoms in patients with functional dyspepsia.
- Trial name
- NCT07008235
- Testing
- Tablet Amitriptyline 10 milligrams, Tablet Trifluoperazine 1 milligrams twice daily, Standard First-Line Therapy
- Where
- Bangladesh
- Volunteers
- 120 people
- Sponsor
- Md. Moktadirul Hoque Shuvo
Functional Dyspepsia
Tradipitant for Functional Dyspepsia
To evaluate the effects of tradipitant relative to placebo on gastric motor functions, satiation, and postprandial symptoms in patients with functional dyspepsia.
- Trial name
- NCT05653310
- Testing
- Tradipitant
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Xiao Jing (Iris) Wang
Functional Dyspepsia
Intestinal Permeability in Children/Adolescents With Functional Dyspepsia
The main purpose of this study is to evaluate whether intestinal permeability and/or serum zonulin concentration is increased in children/adolescents with functional dyspepsia (FD).
- Trial name
- NCT00363597
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Dyspepsia
The Predictive Value of Alarm Symptoms in Patients With Dyspepsia Based on Roman IV
Functional dyspepsia is one of the most common gastrointestinal disorders (FGIDs) encountered in clinical practice.Clinical diagnosis is notoriously unreliable in diagnosing the underlying cause of dyspepsia,but a number of alarm…
- Trial name
- NCT03479528
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Tongue Coating Thickness
Evaluation on the Availability of Tongue Diagnosis System
The aim of the proposed study is to investigate the agreement between the measurement of the tongue diagnosis system (TDS) and the conventional way of tongue diagnosis about the tongue coating thickness (TCT) in the tongue…
- Trial name
- NCT01864837
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Korea Health Industry Development Institute
Dyspepsia
Evaluation of Food Hypersensitivity in Children/Adolescents With Functional Dyspepsia
The main purpose of this study is to determine if standard and investigational tests used to help diagnose and treat food allergies can provide information that will be useful in determining the cause of dyspepsia and helpful in…
- Trial name
- NCT00328679
- Testing
- in vitro and in vivo allergy testing
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Children's Mercy Hospital Kansas City