Clinical trials: Dysphagia, completed
GERD, Hiatal Hernia
Long-term Follow-up After Hiatal Hernia Repair by Tension-free Mesh Closure or Simple Suturing
10 years of follow-up after surgery for hiatal hernia by tension-free mesh closure or simple suturing.
- Conditions
- GERD, Hiatal Hernia, Dysphagia, Esophageal, Quality of Life
- Trial name
- NCT05069493
- Testing
- simple suturing, mesh
- Where
- Sweden
- Volunteers
- 103 people
- Sponsor
- Karolinska University Hospital
GERD
Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients
Researchers are trying to determine if abdominal breathing exercises can reduce symptoms associated with GERD (Gastroesophageal reflux disease).
- Trial name
- NCT04120025
- Testing
- Diaphragm Training
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Mayo Clinic
Gastroesophageal Reflux Disease, Health Economics
Economic Impact of Guidelines for Gastroesophageal Reflux Disease
This is a series of two prospective studies based on the Department of Veterans Affairs drug treatment guideline for the pharmacologic management of gastroesophageal reflux disease.
- Trial name
- NCT00057174
- Testing
- Disease management of gastroesophageal reflux disease
- Where
- United States
- Volunteers
- 484 people
- Sponsor
- US Department of Veterans Affairs
Constriction, Pathological
Fully Coated, Removable, Self-expanding Oesophageal Stents for Preventing Strictures Following Complete Barretts Excision.
The purpose of this study is to investigate whether preventative placement of a removable oesophageal stent reduces the rate of scar tissue, or stricture formation after removing the precancerous or early cancerous Barrett's…
- Trial name
- CBE-001-SEOS (NCT01554280)
- Testing
- Fully coated, removable , self-expanding oesophageal stent
- Where
- Australia
- Volunteers
- 12 people
- Sponsor
- Professor Michael Bourke
Stroke, Dysphagia
Investigation of The Effects of Different Exercise Methods on Swallowing Function in Stroke Patients
The aim of this study is to examine the effects of PNF (proprioceptive neuromuscular facilitation) and CTAR (Chin Tuck Against Resistance) exercises on swallowing rehabilitation in stroke patients.
- Conditions
- Stroke, Dysphagia, Swallowing Disorder
- Trial name
- NCT05678686
- Testing
- Active Comparator: Routine Exercise Group, Experimental: PNF Exercise, Experimental: CTAR Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Karamanoğlu Mehmetbey University
Otitis Media With Effusion
Suitable Method for Routine Diagnostics of EER in Children With Otitis Media With Effusion
The aim of the study was detection of pepsin in effusion in children with OME using Peptest as new quick and cheap method of detection and comparison results with results of other studies in which pepsin was detected by more…
- Trial name
- NCT02183974
- Testing
- Peptest
- Where
- Czechia
- Volunteers
- 44 people
- Sponsor
- University Hospital Ostrava
Paraesophageal Hernia, Gastro Esophageal Reflux
Partial Versus Total Fundoplication in the Surgical Repair of Para-esophageal Hernia.
Short-term follow up after surgery of para-esophageal hernia comparing two different types of fundoplication
- Trial name
- NCT04436159
- Testing
- Addition of 360 fundoplication after crural closure, Addition of 180 posterior fundoplication after crural closure
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Karolinska University Hospital
Gastroesophageal Reflux Disease
A Study to Evaluate the Effect of Lansoprazole on Infants With Gastroesophageal Reflux Disease.
The purpose of this study is to understand how quickly lansoprazole, once daily (QD), improves feeding in premature babies or babies less than 28 days of age.
- Trial name
- NCT00220818
- Testing
- Lansoprazole
- Volunteers
- 24 people
- Sponsor
- Takeda
Sedation for Gastroenteric Endoscopic Procedure, Deglutition Disorders
Valuation of Swallowing in Patient Sedated for Gastroenteric Endoscopic Procedure
Aim of this study is to evaluate swallowing functionality in patient sedated for gastroenteric endoscopic procedure. Swallowing will be study by laryngeal fibroscopy and evaluate using Penetration-Aspiration Scale and Aspiration…
- Conditions
- Sedation for Gastroenteric Endoscopic Procedure, Deglutition Disorders, Aspiration of Food
- Trial name
- SwallSed (NCT01789424)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Ospedale San Raffaele
Dysphagia, Oropharyngeal
AspiRATE: Novel Intervention to Acoustically Detect Silent Aspiration in Acquired Dysphagia.
This study will investigate whether silent aspiration during swallowing can reliably be detected using acoustic signal processing plus pulse oximetry.
- Trial name
- AspiRATE (NCT03676582)
- Testing
- Acoustic analysis plus pulse oximetry
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Cervical Spine
Effect of Local Steroid Application on a Cervical Plate Versus Intravenous Steroids on Dysphagia Following Anterior Cervical Discectomy and Fusion (ACDF)
Local application of steroids in ACDF surgery will lead to decreased incidence of dysphagia compared to intravenous steroids or a control group
- Trial name
- NCT02577991
- Testing
- Decadron, Triamcinolone
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
GERD
Canadian, Multi-Centre Study of Symptom Burden and Clinical Management in Subjects With GERD
This is a cross-sectional study of symptom burden and clinical management. A subset of patients who have attended the Primary Care (PC) office with reflux symptoms during a retrospective period of 4 months (Index Visit) are…
- Trial name
- RANGE (NCT00634023)
- Where
- 15 sites in Canada
- Volunteers
- 500 people
- Sponsor
- AstraZeneca
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Gastroesophageal Reflux Disease
Scintigraphy Study to Compare the Antireflux Activity of the Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects
Primary Objective: Pharmacodynamics: assessment and comparison by gamma scintigraphy of the gastric retention of alginate rafts (raft performance) of Z0063 to the effect of Gaviscon Double Action Tablets, in healthy adult…
- Trial name
- NCT03065816
- Testing
- Z0063, Gaviscon
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sanofi
GERD
Response Surface Pathway Design With Two Interventional- and One Response Variable in Estimating Minimum Efficacy Dose
Response Surface Pathway (RSP) design was previously developed for dose-finding studies with one interventional and one response variable, but RSP to higher dimensions is requested.
- Trial name
- NCT03568825
- Testing
- Osteopatic Manual Therapy (OMT)
- Volunteers
- 15 people
- Sponsor
- Meddoc
Asthma, GERD
Safety and Efficacy Study to Determine Anti-Asthmatic Effect of Esomeprazole Magnesium; Nexium Reflux Asthma
The purpose of this study is to determine whether treatment with esomeprazole for 6 months will improve asthma in adult patients with moderate to severe asthma and symptoms of gastroesophageal reflux disease.
- Trial name
- RELAX (NCT00317044)
- Testing
- Esomeprazole
- Where
- 130 sites in United States, Argentina and 12 more
- Volunteers
- 961 people
- Sponsor
- AstraZeneca
Obesity, GERD
One Anastomosis Gastric Bypass With Excluded Stomach Fundoplication: FundoRing vs Nissen vs OAGB Without Fundoplication
Background and study aims: Currently, one anastomosis Gastric Bypass (OAGB) is a common bariatric procedure. Obesity and gastroesophageal reflux disease (GERD) are steadily increasing world weight and antireflux surgery must be…
- Trial name
- FundoRing (NCT04828733)
- Testing
- laparoscopic one anastomosis gastric bypass with excluded stomach fundoplication: FundoRingOAGB and suture cruroplasty, laparoscopic one anastomosis gastric bypass with excluded stomach Nissen fundoplication and suture cruroplasty, Standard laparoscopic one anastomosis gastric bypass with cruroplasty. Not used fundoplication.
- Where
- Kazakhstan
- Volunteers
- 150 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
GERD, Esophagitis
Esophageal Monitoring Device for Assessing Mucosal Impedance
The investigators are looking at a novel approach to measuring gastroesophageal reflux disease (GERD) damage and reducing the need for costly and less optimal testing presently used for diagnostic and treatment purposes.
- Trial name
- NCT01556919
- Testing
- Standard of care endoscopy
- Where
- United States
- Volunteers
- 429 people
- Sponsor
- Vanderbilt University
Stroke
Changes of Swallowing Function and Oropharyngeal Muscle Mass on Sonography After Comprehensive Swallowing Therapy and Neuromuscular Electrical Stimulation in Stroke Patients With Dysphagia
1. The inter-rater and intra-rater reliability of sonography. 2. To explore that sonography is a clinically practical tool for assessing the changes of oropharyngeal muscles mass. 3.
- Trial name
- NCT04728737
- Testing
- swallowing therapy, IOPI therapy, neuromuscular electrical stimulation (NMES) therapy
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Gastroesophageal Reflux Disease (GERD)
Retrospective Observational Study on GERD Management in General Hospitals in Korea
A RetrospectiVe ObservatIoNal Study of a CurrEnt Status and its Management of GERD (GastroEsophageal Reflux Disease) in General HOspitals in Korea
- Trial name
- VINCERO (NCT06974903)
- Where
- South Korea
- Volunteers
- 13,750 people
- Sponsor
- Chong Kun Dang Pharmaceutical
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.