Clinical trials: Dysphagia
GERD
Intraoperative Endomanometric Laparoscopic Nissen Fundoplication Improves Postoperative Outcomes
Laparoscopic Nissen fundoplication (LNF) is a surgical intervention for gastroesophageal reflux disease (GERD); however, it can be followed by recurrent symptoms or complications that may affect patient satisfaction.
- Trial name
- NCT05851794
- Testing
- endomanometric guided LNF, laparoscopic Nissen fundoplication alone
- Volunteers
- 360 people
- Sponsor
- Zagazig University
Parkinson Disease
Impact of Myofascial Release on Dysphagia in Parkinson's Disease Patients
The goal of this clinical trial is to explore Clinical Effect of Myofascial Release Therapy in Dysphagic Parkinson's Patients. The main question it aims to answer is: Can Myofascial Release Therapy improve swallowing function in…
- Trial name
- NCT06328296
- Testing
- Rehabilitation treatment, Myofascial Release Therapy
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Oropharyngeal Dysphagia, Pneumonia
Health Education to Caregivers to Reduce Aspiration Pneumonia
Randomized clinical study with a control group for assessing the decrease in the incidence of pneumonia, in a 12-month follow-up, in older people with cognitive impairment, risk of bronchial aspiration, risk of malnutrition and…
- Conditions
- Oropharyngeal Dysphagia, Pneumonia, Malnutrition
- Trial name
- HECGPN (NCT05405829)
- Testing
- Health education
- Where
- Spain
- Volunteers
- 178 people
- Sponsor
- Universitat Internacional de Catalunya
Head and Neck Cancer
Pre-treatment Exercises Versus Post-treatment Exercises for Dysphagia
The purpose of this project is to determine if pre-treatment swallowing exercises can improve post-treatment swallowing function in patients undergoing radiation with or without chemotherapy for advanced squamous cell carcinoma…
- Trial name
- NCT00584129
- Testing
- Pre-treatment swallowing exercises, Post-treatment swallowing exercises.
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Alabama at Birmingham
Dysphagia
Anterior Cervical Discectomy and Fusion (ACDF) - Behavioral Intervention
This study will prospectively recruit and enroll patients undergoing primary Anterior Cervical Discectomy and Fusion (ACDF) surgeries at NYU Langone.
- Trial name
- NCT06520579
- Testing
- Proactive pharyngeal-laryngeal Exercise Program, Premier Protein Clear ® High Protein, Hydration Counseling
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Deglutition Disorders, Dysphagia
AI-Enabled Mobile App for Safe Eating in Older Adults With Dysphagia
Difficulty swallowing (called dysphagia) is common in older adults and can make eating and drinking unsafe. It may lead to serious problems such as choking, lung infections, poor nutrition, and reduced quality of life.
- Trial name
- NCT07654088
- Testing
- AI-Enabled Mobile Application plus Standard Care, Standard Dysphagia Education
- Where
- Hong Kong
- Volunteers
- 332 people
- Sponsor
- KAM Chi Shan Anna
Head Neck Cancer, Oral Cancer
Swallowing Function in Patients With Head and Neck Cancers
Head and neck cancer (HNC) is the sixth most common cancer worldwide, accounting for 2.8% of all malignancies. The presence of tumor itself, as well as the treatment, can result in neuromuscular damage affecting any stage of the…
- Trial name
- NCT05833841
- Testing
- Surface Electromyography and Video fluoroscopy
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Banaras Hindu University
Oropharyngeal Dysphagia, Deglutition Disorders
Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia
Oropharyngeal dysphagia induces aspirations which could be responsible of aspiration pneumonia and denutrition. It could be present in the majority of central neurological disease (degenerative or vascular disease), which…
- Trial name
- TENSDEG (NCT01971320)
- Testing
- Urostim I stimulation
- Where
- 6 sites in France
- Volunteers
- 2 people
- Sponsor
- University Hospital, Rouen
Gastroesophageal Reflux Disease and Esophageal Motility Disorders
NEQOL Survey Spanish Validation in a Hispanic Clinic Based Population
Chronic esophageal disorders affect approximately one third part of global population, with a deleterious impact in the quality of life of patients.
- Trial name
- NCT02959424
- Testing
- Spanish Northwestern Esophageal Quality of Life questionnaire
- Where
- Ecuador
- Volunteers
- 385 people
- Sponsor
- Carlos Robles-Medranda
Paralytic Stroke, Cough
Diaphragmatic Function in Stroke Patients.
This study attempts to elucidate whether stroke patients with dysphagia have reduced diaphragm movement during voluntary coughing, and also during deep inspiration and expiration than stroke patients without dysphagia.
- Trial name
- NCT01637649
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Eosinophilic Esophagitis
Esophageal Motility in Eosinophilic Esophagitis Evaluated by High Resolution Manometry.
Esophageal Motility in eosinophilic esophagitis will be evaluated by High Resolution Manometry before and after medical treatment - motility is suspected to change/improve after therapy.
- Trial name
- HIMEOS (NCT02331849)
- Testing
- High resolution manometry (HRM)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Technical University of Munich
Acute Stroke, Dysphagia
Improving SWAllowing After Stroke With Transcranial Direct Current Stimulation
In the acute phase of stroke, dysphagia (difficulty/inability to swallow) is a common problem that can have serious consequences such as aspiration pneumonia, increased lenght of hospitalisation, and death.
- Trial name
- iSWAT (NCT01758991)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Acute Stroke, Dysphagia
Prediction of Functional Health Status and Aspiration Using Multiple Dysphagia Scales Over 6 Months After Acute Stroke
In order to discover dysphagia scales, which shows meaningful predictability of aspiration and functional health status in patients with acute stroke, authors plan to find out more predictable indicators than existing…
- Trial name
- NCT03787524
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Ulsan University Hospital
Morbid Obesity, Gastroesophageal Reflux Disease
Effect of RING on Gastroesophageal Reflux (GERD) After RYGBP
Silastic rings have been used around the gastric pouch in order to promote better weight loss after Roux-and-Y gastric bypass surgery ( RYGBP).
- Conditions
- Morbid Obesity, Gastroesophageal Reflux Disease, Vomiting
- Trial name
- RING (NCT01212835)
- Testing
- RYGBP-RING
- Where
- 3 sites in Brazil
- Volunteers
- 114 people
- Sponsor
- Clinica Gastrobese
Esophageal Motility Disorders
Effect of Esophageal Contractile Reserve on Changes in Esophageal Motility and Symptoms After ARS in Patients With GERD
rapid swallow (MRS) can assess the contractile reserve capacity of the oesophageal body and identify and diagnose oesophageal motility disorders, but the impact of preoperative oesophageal reserve capacity on postoperative…
- Trial name
- NCT05380791
- Testing
- Follow-up visits
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Shandong University
Gastroesophageal Reflux Disease (GERD)
A Study of the Safety and Effectiveness of Rabeprazole for the Treatment of Gastroesophageal Reflux Disease (GERD) in Pediatric Patients
The purpose of the study is to access the effectiveness and safety of oral rabeprazole in the treatment of acid-related disorders in pediatric patients, focusing specifically on the manifestation of GERD (symptomatic and erosive…
- Trial name
- NCT00787891
- Testing
- rabeprazole
- Volunteers
- 127 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Stroke
Complementary Acupuncture Treatment of Dysphagia in Stroke
A Taiwanese study pointed out that stroke patients who have language barriers, dysphagia, and aspiration pneumonia are more likely to suffer from prolonged hospitalization.
- Trial name
- NCT05429424
- Testing
- Verum acupuncture group
- Where
- Taiwan
- Volunteers
- 336 people
- Sponsor
- China Medical University Hospital
Obesity & Overweight, Gastroesophageal Reflux Disease
Effect of Omeprazole on Gut Microbiota in Adults With Obesity and GERD
This randomized, open-label, parallel-group study will evaluate the effect of short-term omeprazole therapy on gut and oral microbiota in adults aged 50-65 years with obesity and symptomatic gastroesophageal reflux disease.
- Trial name
- NCT07850960
- Testing
- Omeprazole, Standard Non-pharmacological Recommendations for GERD
- Where
- Russia
- Volunteers
- 26 people
- Sponsor
- Federal State Budgetary Scientific Institution
Deglutition Disorders
Validation of a Revised Version of the Danish McGill Ingestive Skills Assessment
The McGill Ingestive Skills Assessment (MISA) for measuring dysphagic clients' functional performance during meals has been previously translated into Danish (MISA-DK) and this translated version validated.
- Trial name
- NCT02328196
- Testing
- The Danish McGill Ingestive Skills Assessment (MISA-DK)
- Where
- Denmark
- Volunteers
- 328 people
- Sponsor
- Metropolitan University College
Swallowing Disorders, Stroke
The Effectiveness of Oral Health in Improving Dysphagia of Patients After Stroke of Swallowing Function and Oral Health Quality of Life
The prevalence of chewing dysphagia in the domestic rehabilitation department ward was about 53.61%.Nasal tube retention of about 31%, due to nasogastric tube feeding, often overlooked oral hygiene, easy to cause respiratory…
- Trial name
- NCT03219346
- Testing
- oral care program
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chang Gung Memorial Hospital