Clinical trials: Dysphagia, completed
GERD
Post-POEM GERD in Patients Undergoing Conventional Versus Oblique Fibers Sparing Posterior Myotomy for Achalasia Cardia
In this study, we will evaluate the incidence of reflux esophagitis between two different techniques of posterior per-oral endoscopic myotomy (POEM) i.e. conventional POEM versus oblique/ sling fiber sparing POEM.
- Trial name
- POEM (NCT04229342)
- Testing
- Per-oral endoscopic myotomy
- Where
- India
- Volunteers
- 114 people
- Sponsor
- Asian Institute of Gastroenterology, India
GERD
The Prospective Observational Study Evaluating the Clinical Profile and Correlation of Subjective and Objective Parameters of GERD in a Tertiary Care Hospital : An Indian Perspective
This prospective, single-center study at AIG Hospitals, Hyderabad, aims to establish normal 24-hour ambulatory esophageal pH-impedance values, including acid exposure time (AET), in 50 healthy Indian adults.
- Trial name
- NCT07919522
- Where
- India
- Volunteers
- 50 people
- Sponsor
- Asian Institute of Gastroenterology, India
Laryngopharyngeal Reflux, Laryngopharyngitis Chronic
Method of Early Diagnosis of Laryngopharyngeal Reflux
The investigator will issue a Patient Information Consent for the participant in the study. 1.Patients will be asked to complete the Reflux Symptom Index questionnaire. Clinical survey, medical history. 2.
- Conditions
- Laryngopharyngeal Reflux, Laryngopharyngitis Chronic, Gastro Esophageal Reflux, Laryngitis
- Trial name
- LPR (NCT04771221)
- Testing
- pH metry, Filling out the questionnaire, Endoscopic laryngoscopy
- Where
- 2 sites in Kazakhstan
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Kazakh Medical University of Continuing Education
Dysphagia, Stroke
Effect of Superficial Neuromuscular Stimulation in Post-stroke Dysphagic Patients.
Swallowing disorder in stroke patients is a significant cause of morbidity and mortality as it can cause aspiration pneumonia. Electrical stimulation has proven to be effective in post-stroke dysphagic patients.10 patients who…
- Trial name
- NCT06321406
- Testing
- NMES (neuromuscular electrical stimulation), Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Kayseri City Hospital
Gastroesophageal Reflux Disease, GERD
Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD?
Purpose: 1. Determine if oral quercetin increases the expression of claudin-4 in the lining of the esophagus of patients with a diagnosis of gastroesophageal reflux disease (GERD); and 2.
- Conditions
- Gastroesophageal Reflux Disease, GERD, Acid Reflux, Reflux
- Trial name
- NCT02226484
- Testing
- Quercetin
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of North Carolina, Chapel Hill
Parkinson's Disease, Dysphagia
Efficacy of Voice Treatment for Parkinson's Disease
The purpose of the research study is to determine the effects of two different kinds of speech treatment on certain behaviors in individuals with parkinson's disease.
- Conditions
- Parkinson's Disease, Dysphagia, Dysarthria
- Trial name
- NCT00123084
- Testing
- Voice/Respiration Treatment, Speech/Articulation Treatment
- Where
- 2 sites in United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
GERD (Gastroesophageal Reflux Disease)
Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult Volunteers
A Randomized, Open-label, Oral in healthy volunteers
- Trial name
- NCT07364838
- Testing
- DW4421
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Gastroesophageal Reflux Disease, Obesity, Morbid
Determination of Change in Reflux Disease After Sleeve Gastrectomy by Intraluminal Impedance and pH-meter
710 / 5.000 Çeviri sonuçları Laparoscopic sleeve gastrectomy (LSG) has become the most common bariatric procedure in obesity. The overall relationship between sleeve gastrectomy and gastroesophageal reflux disease is still…
- Trial name
- NCT05405816
- Testing
- laparoscopic sleeve gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Gastroesophageal Reflux
Verification Study on Lafutidine in Mild Reflux Oesophagitis - Double Blind Controlled Study With Famotidine -
The purpose of the study is to verify superiority of the lafutidine group over the placebo group and non-inferiority to the famotidine group in terms of endoscopic healing rate of the patients with mild reflux oesophagitis.
- Trial name
- NCT00229424
- Testing
- Lafutidine, Famotidine
- Where
- Japan
- Volunteers
- 325 people
- Sponsor
- Taiho Pharmaceutical Co., Ltd.
Dysphagia
Madrid - Tolerance and Acceptability Study
Tolerance and Acceptability of a gum based thickener.
- Trial name
- NCT03834896
- Testing
- AYMES MADRID
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Aymes International Limited
Dysphagia
Tongue Pressure Profile Training for Dysphagia Post Stroke
People with swallowing impairment experience particular difficulty swallowing thin liquids safely; the fast flow of liquids makes them difficult to control.
- Trial name
- TPPT (NCT01370083)
- Testing
- Tongue Pressure Profile Training, Tongue-Pressure Strength-and-Accuracy Training
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Toronto Rehabilitation Institute
Gastroesophageal Reflux, Dysphagia
Establishing Pressures at the EGJ During Diaphragmatic Breathing Using High-resolution Esophageal Manometry
The goal of this study is to determine which position, maneuvers or combination thereof generates the highest pressure at the EGJ as assessed by high-resolution esophageal manometry and thus greater or more robust contraction of…
- Conditions
- Gastroesophageal Reflux, Dysphagia, Esophageal Motility Disorders
- Trial name
- NCT06329583
- Testing
- diaphragmatic breathing
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Vonoprazan, Proton Pump Inhibitor
Therapeutic Effect of Vonoprazan Versus Dexlansoprazole in Treatment of Gastroesophageal Reflux Disease
Gastroenterologists are often hesitated about whether to use the well known PPI in treatment of GERD or the usage of new H/K ATPase inhibitors so its highly needed to test the benefit of each class in Egyptian population to help…
- Conditions
- Vonoprazan, Proton Pump Inhibitor, Gastroesophageal Reflux Disease
- Trial name
- NCT06778395
- Testing
- Dexlansoprazole 60 mg, Vonoprazan 20 mg bid
- Where
- Egypt
- Volunteers
- 136 people
- Sponsor
- Ayman Magd Eldin Mohammad Sadek
Parkinson Disease, Dysphagia
Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease
Parkinson's disease (PD) is a chronic, degenerative disease described by motors and non-motors symptoms. Changes in swallowing and respiratory dynamics increase risk of tracheal aspiration largely responsible for increased…
- Trial name
- NCT01420796
- Testing
- Swallowing exercise, Breathing Exercises, Swallowing and breathing exercises
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Federal University of Bahia
Pharyngitis
A Study of Flurbiprofen 8.75 mg Lozenge in Patients With Pharyngitis
The purposes of this study is to demonstrate the analgesic efficacy of flurbiprofen 8.75 mg lozenge compared to its vehicle lozenge and to demonstrate the safety of the flurbiprofen lozenge throughout the course of treating sore…
- Trial name
- NCT01048866
- Testing
- flurbiprofen, acetaminophen 650mg
- Where
- United States
- Volunteers
- 198 people
- Sponsor
- Reckitt Benckiser LLC
GERD, Quality of Life
The Effect of Lifestyle-Adjustments Prior to Medical Treatment on the Effect of Medical Treatment in Reflux Patients
The purpose of this study is to determine whether the improvement in the quality of life after an initial treatment with esomeprazole 40mg for reflux disease is the same in patients who have already made lifestyle-adjustments as…
- Trial name
- NCT00524251
- Testing
- esomeprazole
- Where
- 54 sites in Netherlands
- Volunteers
- 990 people
- Sponsor
- AstraZeneca
Esophagitis, Gastro Oesophageal Reflux Disease
Clinical Investigation to Assess the Acid Neutralisation Activity of a Calcite Chewing Gum
This investigation is designed to evaluate the acid neutralisation action of a new test product versus unmatched placebo.
- Trial name
- NCT05129670
- Testing
- Calcite chewing gum
- Where
- Ireland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Deglutition Disorders, Intensive Care Unit Syndrome
Removal of Nasogastric Feeding Tube Post Extubation in ICU : a Prospective Randomized Trial
Post-extubation dysphagia (PED) is a frequent but still underestimated condition in the intensive care units (ICU). In the international literature, the manifestations and consequences of PED lead to intra- and post-intensive…
- Conditions
- Deglutition Disorders, Intensive Care Unit Syndrome, Swallowing Disorder, Feeding or Eating Disorder
- Trial name
- FIRST (NCT05795569)
- Testing
- Nasogastric Tube removal during extubation, Yale Swallow Protocol, Classif Nasogastric Tube Management
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Drug Interaction, GERD (Gastroesophageal Reflux Disease)
A Study to Investigate the Effect of Linaprazan Glurate on the Pharmacokinetics of Amoxicillin
This is an open, single arm, single-center Phase I trial designed to evaluate the effect of seven days repeated oral doses of linaprazan glurate on the pharmacokinetics (PK) of repeated doses of amoxicillin in healthy male and…
- Conditions
- Drug Interaction, GERD (Gastroesophageal Reflux Disease), Safety, and Tolerability
- Trial name
- NCT07308041
- Testing
- Drug Drug Interaction
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cinclus Pharma Holding AB
DYSPHAGIA
Evaluation Of The Effectiveness Of Safe Nutrition Program Applied To Acute Stroke Patients With Dysphagia
It was planned in a quasi-experimental design with a non-randomized control group. The study was planned to be completed in three stages: control, preparation and intervention periods.
- Trial name
- NCT06269575
- Testing
- SAFE NUTRITION PROGRAM
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Istanbul University - Cerrahpasa
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