Clinical trials: Dysphonia
Dysphonia Resulting From Vocal Fold Scarring, Age-related Dysphonia
Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia
The objectives of this study are to assess the safety of azficel-T treatment for dysphonia related to vocal fold function and to evaluate the efficacy of azficel-T for the treatment of dysphonia related to vocal fold function.
- Trial name
- NCT02120781
- Testing
- Azficel-T (autologous fibroblasts)
- Where
- 3 sites in United States
- Volunteers
- 21 people
- Sponsor
- Castle Creek Biosciences, LLC.
Functional Voice Disorder, Psychogenic Voice Disorder
Autonomic Dysfunction in Functional Dysphonia
The first objective of this research project is to compare the occurrence and frequency of symptoms and/or disorders related to autonomic dysfunction in patients with functional dysphonia with gender- and age-matched vocally…
- Conditions
- Functional Voice Disorder, Psychogenic Voice Disorder, Muscle Tension Dysphonia
- Trial name
- NCT06100601
- Testing
- ANS regulation therapy, conventional voice therapy (CVT), ANS regulation therapy + CVT
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Ghent
Anesthesia, Pain, Postoperative
The Evaluation of the Effect of Preoperatively Applied Throat Lozenge
Purpose:The aim of this study is to evaluate the effect of preoperative throat lozenge on pain relief in the postoperative period of the mucosal damage caused by intubation in patients who underwent operations in the head and…
- Trial name
- NCT06114771
- Testing
- strepsilis
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Dysphonia
Artificial Intelligence and Benign Lesions of Vocal Folds Recognition
The development of Artificial Intelligence (AI), the evolution of voice technology, progresses in audio signal analysis, and natural language processing/understanding methods have opened the way to numerous potential applications…
- Trial name
- NCT05754606
- Testing
- Audio recordings
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia
Dysphagia and Dysphonia in Anterior Cervical Spinal Surgery
Introduction: The anterior cervical approach is used to treat a variety of spinal disorders; among these, the Smith-Robinson approach is the most commonly used, as it allows access to discs, bony structures, and anterior lesions…
- Conditions
- Dysphagia After Anterior Cervical Decompression and Fusion of the Spine, Dysphonia, Anterior Cervical Spinal Surgery
- Trial name
- NCT07713693
- Testing
- Fiberoptic Endoscopic Evaluation of Swallowing, 30-item questionnaire designed to assess the impact of speech dysfunction on the patient's daily life, EAT-10 questionnaire
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Postoperative Sore Throat, Endotracheal Intubation
Scheduled Endotracheal Tube Cuff Pressure Management and Postoperative Sore Throat
This randomized controlled trial evaluated whether scheduled measurement and adjustment of endotracheal tube cuff pressure using a handheld manometer could reduce postoperative sore throat in adults undergoing elective surgery…
- Trial name
- NCT07842081
- Testing
- Handheld Endotracheal Tube Cuff Manometer, Pilot-Balloon Palpation
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people
- Sponsor
- Hitit University
Hypocalcemia, Vitamin D Deficiency
The Effect of Preoperative Oral Dexamethasone Supplementation on the Outcome of Thyroidectomised Patients.
Glucocorticoids are well known for their analgesic, anti-inflammatory, immunomodulatory and anti-emetic effects. Recovery time after thyroid surgery may depend on several factors, such as postoperative pain, nausea and vomiting…
- Conditions
- Hypocalcemia, Vitamin D Deficiency, Postoperative Complications, Postoperative Nausea
- Trial name
- Dexa (NCT04412694)
- Testing
- Dexamethasone oral tablet 8mg (Dexamethasone Krka tablets(8mg), Warsaw, Poland)., Preoparative blood laboratory tests, Postoperative laboratory blood tests at 6 hour
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Lodz
Dystonia
The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias
Dystonia is a disorder characterized by excessive involuntary contraction of muscles with repetitive and patterned movements. The isolated dystonias are the most common type of dystonia and include Limb dystonias (like writer's…
- Trial name
- DCP (NCT01373424)
- Where
- 42 sites in United States, Australia and 5 more
- Volunteers
- 3,265 people
- Sponsor
- Emory University
Vocal Fold Nodules, Muscle Tension Dysphonia
Preliminary Study 2 to Test the Effects of Ambulatory Voice Biofeedback
Patients with vocal hyperfunction will undergo standard of care voice therapy with ambulatory voice monitoring before therapy and after the first 3 voice therapy sessions.
- Trial name
- NCT03416868
- Testing
- Ambulatory voice biofeedback
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Massachusetts General Hospital
Herpes Esophagitis, Vocal Fold Palsy
Unusual Clinical Findings of Herpes Esophagitis
Herpes esophagitis presents a clinical diagnostic challenge. The investigators report the first case of herpes esophagitis presenting as vocal fold palsy in an immunocompetent host.
- Trial name
- NCT01501526
- Where
- Taiwan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Dysphonia, Connective Tissue Disease
Characterization of "Bamboo" and Other Vocal Cord Lesions Responsible for Dysphonia in Patients With Systemic Autoimmune Diseases (BAMBOO)
The goal of this multicenter retrospective observational study is to provide an inventory of the specific and non specific cord vocal lesions that can cause dysphonia in patients with systemic autoimmune diseases.
- Conditions
- Dysphonia, Connective Tissue Disease, Vasculitis
- Trial name
- BAMBOO (NCT06779799)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Laryngeal Dystonia
Brain-Computer Interfaces in Laryngeal Dystonia
The researchers will develop and evaluate the use of adaptive closed-loop brain-computer interface therapeutic intervention in laryngeal dystonia.
- Trial name
- NCT04421365
- Testing
- neurofeedback brain-computer interface (BCI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kristina Simonyan
Thyroid Diseases, Postoperative Voice Change
Oxidized Regenerated Cellulose and Voice Quality After Total Thyroidectomy
This randomized controlled trial evaluated whether placement of oxidized regenerated cellulose (ORC) over the recurrent laryngeal nerves during total thyroidectomy affects early postoperative voice quality.
- Trial name
- NCT07681557
- Testing
- Oxidized Regenerated Cellulose
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara University
Laryngeal Injury, Hoarseness
Innovative Endotracheal Tube Design Reduces Postoperative Laryngeal Injury
The goal of this randomized clinical trial is to compare two different orotracheal tubes in patients which require orotracheal intubation for general anesthesia.
- Conditions
- Laryngeal Injury, Hoarseness, Cough, Sore-throat
- Trial name
- Triglotix® (NCT06108271)
- Testing
- Triglotix®, Conventional endotracheal tube
- Where
- Spain
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital of the Nuestra Señora de Candelaria
Temporomandibular Joint Disorders, Voice Change
Impact of Temporomandibular Joint Dysfunction on Objective and Subjective Vocal Measures
The present study aims to investigate the impact of temporomandibular joint dysfunction (TMD) on objective and subjective vocal parameters and the quality of life in affected patients.
- Trial name
- NCT06046521
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dystonia, Primary, Dysarthria
Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular
To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement…
- Conditions
- Dystonia, Primary, Dysarthria, Dysphonia, Dysphagia
- Trial name
- DOM (NCT03380676)
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Laryngeal Nerve Injuries, Thyroidectomy
Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery
The frequent occurrence of impaired function in the external branch of the superior laryngeal nerves following thyroid surgery is recognized as a prevalent complication leading to a diminished quality of life.
- Conditions
- Laryngeal Nerve Injuries, Thyroidectomy, Voice Change
- Trial name
- NCT06002984
- Testing
- Using Neuromonitoring to find EBSLN
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Dysphonia, Vocal Cord Cyst
Voice Rest Versus Hypofunctional Whispering After Phonosurgery
This randomized controlled trial compares two postoperative voice behavior protocols in patients undergoing microlaryngeal surgery (phonosurgery) for benign vocal fold lesions such as polyps, cysts, and Reinke's edema.
- Conditions
- Dysphonia, Vocal Cord Cyst, Vocal Cord Polyp, Bening Vocal Cord Lesions
- Trial name
- NCT07704125
- Testing
- Absolute Voice Rest, Hypofunctional Whispering
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Celal Emre Çavlan
Dysphonia, Fibromyalgia
Relationship Between Dysphonia And Anxiety In Fibromyalgia
Our aim in conducting this study is to determine the relationship between voice disorders and anxiety in patients with fibromyalgia syndrome (FS).
- Conditions
- Dysphonia, Fibromyalgia, Anxiety Disorders
- Trial name
- NCT05410756
- Testing
- Assessment of Voice Quality and Function
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Phonation Disorder, Spastic Dysphonia
Sensory Function in Idiopathic Voice Disorders
This research study is designed to improve understanding about voice disorders that are due to uncontrolled muscle contractions affecting the voice box.
- Conditions
- Phonation Disorder, Spastic Dysphonia, Voice Disorder
- Trial name
- NCT00001922
- Where
- United States
- Volunteers
- 370 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)