Clinical trials: Dysphoria
Gender Dysphoria, Adolescent
Counseling Among Gender Diverse Adolescents Who Use Depot Medroxyprogesterone
Recommendations regarding contraceptive counseling and reproductive health differ amongst transgender and gender diverse (TGD) youth compared to cis-gender youth.
- Trial name
- NCT05726903
- Testing
- Depo-subQ Provera Injectable Product
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Gender Dysphoria
Gender Dysphoria and Transition
Persons with gender dysphoria present the difficulties of access to health care. Little time is devoted to education of health professionals about the care of transgender persons.
- Trial name
- DyGePeT (NCT04265885)
- Testing
- collection of testimonies from transgender people
- Volunteers
- 10 people
- Sponsor
- Central Hospital, Nancy, France
Gender Dysphoria, Adult, Blood Coagulation
Comparing the Effects of Sublingual Estradiol Treatment Versus Oral Estradiol With Cyproterone Acetate (CPA) Treatment on The Coagulation System in Transgender Women: A Prospective, Controlled Cohort Study
The goal of this clinical trial is to learn about the effects of different routes of estradiol administration on blood clotting in transgender women starting gender-affirming hormone therapy.
- Conditions
- Gender Dysphoria, Adult, Blood Coagulation, Coagulation Factors, Transgender Persons, M01.777.500
- Trial name
- NCT07145281
- Testing
- Estradiol (E2), Cyproterone Acetate (Androcur, BAY94-8367)
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Gender Incongruence, Transgenderism
Effect of Transgender Therapy on Muscle, Fat and Tissue Receptors
The purpose of this research is to find out if hormone therapy in transgender subjects' changes hormone receptors in blood, muscle and fat; fat production; muscle production; and inflammation processes.
- Trial name
- NCT04551144
- Testing
- testosterone cypionate, Estradiol Valerate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- St. Louis University
Gender Dysphoria, Gender Identity Disorder
Sexuality in Transmen During Hormone and Operative Treatment
With this analysis the investigators aim at discovering a difference in sexuality between transmen, cissexual women and cissexual men. A potential impact of body satisfaction will also be explored.
- Conditions
- Gender Dysphoria, Gender Identity Disorder, Transsexualism, Body Image
- Trial name
- Transmann (NCT03637920)
- Where
- Austria
- Volunteers
- 160 people
- Sponsor
- Medical University of Graz
Gender Dysphoria in Adolescents and Adults
Transgender Therapeutic Support Groups
This study seeks to explore the effects for transgender people undergoing surgical interventions of participating in pre/post-surgical therapeutic support groups in order to assess the value of adding these programs to hospital…
- Trial name
- NCT04217707
- Testing
- Pre- and Post-Surgical Transgender Therapeutic Support Group
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Denver Health and Hospital Authority
Transgender, Gender Incongruence
The Effect of Tucking on Semen Quality of Adult Trans Women
Because gender-affirming hormone therapy (GAHT) can lead to fertility impairment, current guidelines and treatment recommendations require that patients be informed about the possibility of fertility preservation prior to…
- Conditions
- Transgender, Gender Incongruence, Fertility Issues
- Trial name
- NCT06530992
- Testing
- tucking break
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Gender Incongruence
Optimizing Individual Health Care for Young People With Gender Incongruence
This observational study focuses on evaluating the effect of the current health care program for Danish children and adolescents with gender incongruence, which was established in January 2016.
- Trial name
- NCT06573177
- Testing
- Referral to the gender identity service.
- Where
- Denmark
- Volunteers
- 1,300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Gender Dysphoria
Cross-sex Hormone Therapy and Neuronal Plasticity
Transgender women (male-to-female) were invited to participate in this study to test the impact of Cross-Sex Hormone Therapy (CSHT) in the brain.
- Trial name
- NCT03651427
- Testing
- Estradiol
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Gender Dysphoria
Understanding Perceived Access and Receipt of Gender-affirming Treatments Among Transgender Veterans
Transgender Veterans (trans Vets) frequently experience gender dysphoria or distress related to discord between their gender identity and birth sex.
- Trial name
- NCT06615401
- Where
- United States
- Volunteers
- 986 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Transgenderism, Erectile Dysfunction
Erectile Aid Use in Post-phalloplasty and Post-metoidioplasty Transgender Patients
This study seeks to explore the various methods used by transgender men for sexual intercourse following phalloplasty or metoidioplasty, focusing on their satisfaction with different erectile aids, as well as the satisfaction of…
- Conditions
- Transgenderism, Erectile Dysfunction, Gender Dysphoria, Sexual Dysfunction
- Trial name
- AID (NCT06639763)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Gender Incongruence, Cardiovascular (CV) Risk
Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway
Gender incongruence, now classified in ICD-11 as a "marked and persistent incongruence between an individual's experienced gender and the gender assigned at birth," is managed in dedicated, multidisciplinary centres that…
- Conditions
- Gender Incongruence, Cardiovascular (CV) Risk, Cardiovascular Disease Risk Factor, Cardiovascular Disease Acute
- Trial name
- CV-TGD (NCT07187947)
- Testing
- Feminizing GAHT, Masculinizing GAHT
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Speech Therapy, Transgender Women
Voice Feminisation in Transgender Women
The voice is a reflection of our identity. In the case of transgender women, there may be a gap between perceived male voice and female appearance.
- Conditions
- Speech Therapy, Transgender Women, Gender Dysphoria
- Trial name
- FemVoc (NCT03899896)
- Where
- France
- Volunteers
- 77 people
- Sponsor
- Central Hospital, Nancy, France
Gender Dysphoria
Gender Identity and Own Body Perception
This study will provide valuable information on the neurobiological underpinning of gender dysphoria (GD) and the effects of sex hormones, and promises to uncover functional or structural neural patterns that could predict…
- Trial name
- NCT04374708
- Testing
- fMRI
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gender Dysphoria
Developmental Correlates and Hormone Therapy Effects in Gender Dysphoria
The aim of the research is to study longitudinally the effects of reassignment hormonotherapy on the connectome of MtF (biological men who are transitioning to the female gender) dysphoric subjects after 6 months of hormone…
- Trial name
- DCHGD (NCT04309760)
- Testing
- MRI
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Premenstrual Dysphoric Disorder
Intranasal PH80 Spray for Acute Management of the Symptoms of Premenstrual Dysphoric Disorder
The objective of this study is to evaluate the effectiveness and safety in double-blind, randomized, placebo-controlled clinical trials of self administered PH80 intranasal spray for the acute management of cycle related symptoms…
- Trial name
- PH80-PMD (NCT01217775)
- Testing
- PH80
- Where
- United States
- Volunteers
- 1,400 people
- Sponsor
- Pherin Pharmaceuticals, Inc.
Gender Incongruence
Transgender In Transition
Prospective trial in gender dysphoric patients who undergo gender-affirming hormone therapy, aiming to investigate psychological, biological and behavioural consequences of hormonal therapy.
- Trial name
- TRANSIT (NCT04028219)
- Testing
- Online surveys
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 750 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Gender Dysphoria
Trans Care: An Online Intervention to Reduce Symptoms of Gender Dysphoria
The current project aims to improve the well-being of trans and nonbinary (TNB) individuals through an online intervention (Trans Care) targeting the reduction of symptoms of gender dysphoria.
- Trial name
- NCT05884307
- Testing
- Trans Care Web App
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Gender Identity, Gender Dysphoria in Adolescents and Adults
Puberty, Testosterone, and Brain Development
Transmasculine youth (female sex assigned at birth, male gender identity) who begin clinical gender affirming hormone therapy (GAHT) with testosterone (T) may experience changes in headache.
- Conditions
- Gender Identity, Gender Dysphoria in Adolescents and Adults, Headache, Transgender
- Trial name
- NCT06670053
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Colorado, Denver