Clinical trials: Dyspnea
COVID-19 Pandemic, Diabetes
Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19
The COVID-19 pandemic has emerged as the most significant public health crisis of the 21st century. As of the end of January 2023, global confirmed cases have exceeded 670 million, with a domestic cumulative total of 10.24…
- Conditions
- COVID-19 Pandemic, Diabetes, Hypertension, Cardiac Disease
- Trial name
- NCT06231225
- Testing
- Incentive Spirometer respiratory training
- Volunteers
- 100 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Chronic Obstructive Pulmonary Disease
Ryme Medical TLD Pilot Study
Targeted lung denervation (TLD) with the Ryme Medical Lung Denervation System in patients with chronic obstructive pulmonary disease (COPD) - Ryme Medical TLD Pilot Study
- Trial name
- NCT05967091
- Testing
- Targeted Lung Denervation
- Where
- 7 sites in Australia, Austria and 4 more
- Volunteers
- 60 people
- Sponsor
- Ryme Medical, Inc.
Dyspnea, Lung Diseases
Effects of Automated Oxygen Titration Alone or With High Flow Nasal Therapy on Dyspnea and Exercise Tolerance
The main purpose of this study is to evaluate the effects of automated oxygen administration (FreeO2 system) alone or with high-flow oxygen on dyspnea and exercise tolerance in people with desaturating chronic lung disease…
- Conditions
- Dyspnea, Lung Diseases, Pulmonary Hypertension, Chronic Obstructive Pulmonary Disease
- Trial name
- NCT05267418
- Testing
- Automated nasal O2 titration with FreeO2
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
Palliative Care, Dyspnea
The Effect of Acupressure on the Management of Dyspnea
Dyspnea can develop at any stage of the disease, but it is more common in the last period of life. Complementary and integrative methods used for dyspnea symptoms include acupuncture, acupressure, visualization techniques, herbal…
- Trial name
- NCT05884450
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Pulmonary Cancer
Multidisciplinary Rehabilitation After Cancer Pulmonis Operation
The purpose of this investigation is to determine the effects of exercise training on quality of life and physical capacity, 3 months and 1 year after radical operation for pulmonary cancer.
- Trial name
- NCT01048762
- Testing
- physical exercise and dyspnoea counseling, home training
- Where
- Denmark
- Volunteers
- 78 people
- Sponsor
- Aalborg University Hospital
Dyspnea, Coma
The Use of a Point-of-care Thoracic Ultrasound Protocol for Hospital Medical Emergency Teams
Study to assess the possible effects of the use of a point-of-care thoracic ultrasound protocol for hospital medical emergency teams (MET)
- Conditions
- Dyspnea, Coma, Hypotension and Shock
- Trial name
- METUS (NCT03214809)
- Testing
- ultrasound protocol
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Rijnstate Hospital
COVID-19
Trial to Study the Adjuvant Benefits of Quercetin Phytosome in Patients With COVID-19
The purpose of this study is to investigate if Quercetin Phytosome is beneficial for the treatment of COVID-19.
- Trial name
- NCT04578158
- Testing
- Standard COVID-19 care, Quercetin Phytosome
- Where
- Pakistan
- Volunteers
- 152 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Heart Failure, Congestive Cardiac Failure
B-type NAtriuretic Peptide In Critically Ill : A Multicentric Diagnostic Study (B-rAPID)
Difficulty in breathing or increased rate of breathing are common causes of admission to intensive care unit. This may be due to heart failure, or other causes such as infection in the lungs.
- Conditions
- Heart Failure, Congestive Cardiac Failure, Dyspnoea
- Trial name
- B-RAPID (NCT01685385)
- Testing
- Patients who will receive the BNP test
- Where
- 4 sites in India
- Volunteers
- 800 people
- Sponsor
- Mahatma Gandhi Institute of Medical Sciences
Chronic Obstructive Pulmonary Disease
Unsupported Arm Exercise and Breathing Strategy in Patients With Chronic Obstructive Pulmonary Disease
Controlling the way people with lung problems breathe during arm exercises may reduce their breathlessness during activities of daily living that require them to lift their arms (i.e.
- Trial name
- NCT00836108
- Testing
- breathing strategy
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- West Park Healthcare Centre
Dyspnea
Inhaled Ondansetron & Dyspnea
"Dyspnea" refers to the awareness of breathing discomfort that is typically experienced during exercise in health and disease. In various participant populations, dyspnea is a predictor of disability and death; and contributes to…
- Trial name
- NCT01851993
- Testing
- Ondansetron
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Tuberculosis
Effects of the Active Cycle of Breathing Technique With and Without Balloon Blowing Therapy in Tuberculosis
The study design will be a randomized controlled trial. The data will be collected from Gulab Devi Teaching Hospital, Lahore. 34 kids aged 8 to 14 years will be randomly assigned either to an experimental group or a control…
- Trial name
- NCT07484490
- Testing
- Active cycle of breathing with Balloon therapy, Active Cycle of breathing
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Chronic Obstructive Pulmonary Disease
Indacaterol Versus Tiotropium on Dynamic Hyperinflation in COPD
Exercise intolerance is a major complain of patients with chronic obstructive pulmonary disease (COPD). Dynamic hyperinflation has been recognized as an important limiting factor responsible for the appearance of intolerable…
- Trial name
- NCT01693003
- Testing
- Indacaterol, Tiotropium
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Irmandade Santa Casa de Misericórdia de Porto Alegre
Ankylosing Spondylitis, Respiratory Distress
Effectiveness of Mobile Respiratory Training in Ankylosing Spondylitis
Introduction and aim; Low functionality of respiratory muscles is frequently observed in various diseases such as chronic obstructive pulmonary disease, cystic fibrosis, idiopathic pulmonary fibrosis, and rheumatological diseases…
- Conditions
- Ankylosing Spondylitis, Respiratory Distress, Exercise Therapy, Breath Tests
- Trial name
- NCT06652984
- Testing
- Exercise 1, Exercise 2
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Uşak University
Obstructive Chronic Bronchitis
Acute Dyspnea After Use of Non-invasive Ventilation in COPD and Emphysema (Deventilation Syndrome)
Acute dyspnea after use of non-invasive ventilation (NIV) is a common phenomenon in patients with COPD and emphysema. This trial aims to document incidence and severity of augmented dyspnea in patients with long term NIV therapy.
- Trial name
- NCT02942134
- Volunteers
- 70 people
- Sponsor
- Felix JF Herth
Pulmonary Disease, Chronic Obstructive
Effect of Expiratory Positive Pressure on Dynamic Hyperinflation and Ability to Exercise With Upper Limbs in COPD
The study will evaluate the effect of positive airway expiratory pressure (EPAP) on patients with chronic obstructive pulmonary disease (COPD) during submaximal upper limb exercise.
- Trial name
- NCT03073564
- Testing
- Endurance test for upper limbs, Functional test
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Obstructive Pulmonary Disease
Effect of Inspiratory Muscle Training on Exercise Performance and Quality of Life in Patients With Chronic Obstructive Pulmonary Disease
The aim is to study effectiveness of inspiratory muscle training as a part of exercise training in patients with Chronic Obstructive Pulmonary Disease (COPD) and if it adds to general exercise training program in regard to…
- Trial name
- NCT02257463
- Testing
- theophylline, long acting bronchodilators (LABD) or combined LABD and inhaled steroids according to GOLD recommendations, peripheral muscles exercise training, inspiratory muscle training
- Volunteers
- 60 people
- Sponsor
- Mansoura University
COPD (With - Without Rehabilitation), Diffuse Interstitial Lung Diseases
Development of a New Tool for Dyspnea Measurement in Chronic Respiratory Diseases
The purpose of this study is the psychometric validation of a self-administered dyspnea questionnaire, usable in clinical practice in order to assess dyspnea and its impact on patients with chronic respiratory diseases.
- Conditions
- COPD (With - Without Rehabilitation), Diffuse Interstitial Lung Diseases, Pulmonary Arterial Hypertension Primary or Secondary (Post Embolic .....), Cystic Fibrosis of the Adult
- Trial name
- DYSLIM (NCT02229994)
- Testing
- Cross sectional psychometric evaluation of a self-administered dyspnea questionnaire.
- Where
- France
- Volunteers
- 199 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Pulmonary Disease, Dyspnea
Breathlessness Exertion and Morphine Sulphate
Breathlessness is an overwhelming symptom affecting tens of thousands of Australians every day. For many people, it persists even when all the underlying causes have been optimally managed (chronic breathlessness).
- Trial name
- BEAMS (NCT02720822)
- Testing
- Morphine Sulfate, Plus laxative (Docusate with senna), FitBit charge HR (Accelerometer)
- Where
- 15 sites in Australia, New Zealand
- Volunteers
- 171 people
- Sponsor
- Flinders University
Asthma, Bronchospasm
Virtual Teach-to-Goal Education vs. Brief Education for Children
The purpose of this study is to evaluate the effectiveness of two different ways to teach hospitalized children how to use a metered dose inhaler and to follow-up after discharge home from the hospital to determine durability of…
- Conditions
- Asthma, Bronchospasm, Shortness of Breath
- Trial name
- V-TTG vs BI (NCT04373499)
- Testing
- Virtual Teach to Goal, Brief Intervention
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Chicago
SARS-CoV 2, COVID
Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19
Brief Summary: SARS-CoV-2 virus infection is known to cause Lung Injury that begins as dyspnea and exercise intolerance, but may rapidly progress to Critical COVID-19 with Respiratory Failure and the need for noninvasive or…
- Conditions
- SARS-CoV 2, COVID, ARDS, ALI
- Trial name
- AVICOVID-3 (NCT05137795)
- Testing
- ZYESAMI™ (aviptadil acetate)
- Sponsor
- APR Applied Pharma Research s.a.