Clinical trials: Dyspnea
ILD
Edmonton Dyspnea Inventory- Validation Study
Breathlessness is a common problem for many patients with Interstitial lung disease (ILD). ILD is a group of lung diseases that cause inflammation (swelling) and scarring in the lung tissue where gas exchange (oxygen and carbon…
- Trial name
- NCT06290635
- Testing
- Breathlessness Assessment Tool
- Where
- 3 sites in Canada, Denmark and 1 more
- Volunteers
- 79 people
- Sponsor
- University of Alberta
Interstitial Lung Disease
Clinical Impact of HOME Oxygen SATURation Measurement (SATURHOME)
The use of saturometry at home is more and more widespread in patients suffering from interstitial pulmonary diseases (IPD), the patients seeing it as reassurance and a concrete way to follow the evolution of their disease.
- Trial name
- SATURHOME (NCT04624191)
- Testing
- Saturation at home
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Laval University
Malignancy
Does Transcranial Magnetic Stimulation of the Cingulate Cortex Modulate the Perception of Dyspnoea?
The treatment we are studying is Transcranial Magnetic Stimulation (TMS). In TMS, an electromagnetic pulse is passed into the brain through a coil placed on the head.
- Trial name
- TMS (NCT00830921)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Oxford
Lung Neoplasms, Breast Neoplasms
Acupuncture for Shortness of Breath in Cancer Patients
The purpose of this study is to determine whether acupuncture is effective in relieving shortness of breath among breast and lung cancer patients.
- Trial name
- NCT00067691
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) Activity: Serotonin Transporter (SERT), Cytokines and Depression (CASCADE Study)
The goal of the study is to look at how genes and certain chemicals in the body are related to depression and chronic obstructive pulmonary disease.
- Trial name
- CASCADE (NCT01074515)
- Where
- 4 sites in United States
- Volunteers
- 350 people
- Sponsor
- University of Washington
Pulmonary Disease, Chronic Obstructive, Health-Related Quality Of Life
Mobile-Application Based Respiratory Rehabilitation For COPD
Abstract Purpose: This study aimed to determine the effect of mobile application-based exercise programs on the quality of life and dyspnea of patients with chronic obstructive pulmonary disease.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Health-Related Quality Of Life, Dyspnea
- Trial name
- NCT05890443
- Testing
- Exercise
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ordu University
COPD, Postural; Defect
Spinal Structure and Mobility in Chronic Obstructive Pulmonary Disease
In recent studies with musculoskeletal system disorders in chronic respiratory patients, it has been reported that postural control is affected in COPD patients.
- Conditions
- COPD, Postural; Defect, Respiratory Function Impaired, Dyspnea
- Trial name
- NCT05021068
- Testing
- Postural Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Izmir Katip Celebi University
Allergy, Respiratory Distress
Primary Allergy and Its Impact on the Occurrence of Respiratory Distress in Infants at 12 Months of Age
The number of people with allergies has been steadily increasing over the years. Symptoms in infants, such as bronchiolitis, gastroesophageal reflux, eczema, or atopic dermatitis, can be early warning signs of allergies in…
- Conditions
- Allergy, Respiratory Distress, Atopic Manifestations, Immediate Postnatal Parameters
- Trial name
- AIRE (NCT07832643)
- Testing
- questionnaire
- Where
- France
- Volunteers
- 508 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Oxygen, Respiratory Insufficiency
INSPIRatory Efforts Estimation Under High-flow Nasal Oxygen
High-flow nasal oxygen (HFNO) is recommended as first-line treatment to prevent intubation in acute hypoxemic respiratory failure and to prevent reintubation after extubation.
- Conditions
- Oxygen, Respiratory Insufficiency, Work of Breathing, Dyspnea
- Trial name
- INSPIRE-Pilot (NCT07228676)
- Testing
- Non-invasive estimation of inspiratory effort
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Poitiers University Hospital
SARS-CoV 2, COVID
Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19
Brief Summary: SARS-CoV-2 virus infection is known to cause Lung Injury that begins as dyspnea and exercise intolerance, but may rapidly progress to Critical COVID-19 with Respiratory Failure and the need for noninvasive or…
- Conditions
- SARS-CoV 2, COVID, ARDS, ALI
- Trial name
- AVICOVID-2 (NCT04360096)
- Testing
- ZYESAMI™ (aviptadil acetate)
- Where
- 13 sites in United States
- Volunteers
- 144 people
- Sponsor
- APR Applied Pharma Research s.a.
Heart Failure
Pathophysiological Mechanisms of Activity-Related Dyspnea in Heart Failure: A Pilot Study
Dyspnea (breathlessness) on exertion is the most prevalent and distressing symptom of heart failure (HF). Nevertheless, the mechanisms of dyspnea in HF remain poorly understood.
- Trial name
- NCT02007486
- Testing
- Cardiopulmonary Exercise Testing
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- McGill University
Neuromuscular Disorders
Screening Questionnaire for Respiratory Muscle Weakness and Sleep-disordered Breathing in Neuromuscular Disorders
It is the aim of this project to develop and validate a German language screening questionnaire for symptoms of respiratory muscle weakness and sleep-disordered breathing (SDB) in patients with neuromuscular disorders.
- Trial name
- NCT02833168
- Testing
- patient-filled questionnaires, spiromanometry
- Where
- 2 sites in Germany
- Volunteers
- 90 people
- Sponsor
- Universität Münster
Acute Decompensated Heart Failure
Gas Exchange for Predicting Hospital Heart Failure Readmissions
To determine whether, and if so, which gas exchange parameters measured on the Shape-HF Cardiopulmonary Exercise Testing System predict 30 and 180 day re-hospitalization in subjects discharged from hospitalization for an episode…
- Trial name
- NCT01960218
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Shape Medical Systems, Inc.
Esophageal Perforation
A 75 Year Old With Dyspnea a Case Report.Observational Study
Clinical Case report Of spontaneous esophageal perforation in a 75 year old man. He prsented with breathlessness and on investigation found to have esophageal perforation
- Trial name
- NCT00422760
- Volunteers
- 1 people
- Sponsor
- Stanley Medical College
Respiratory Distress, Hypoglycemia
Adrenaline Injections to Children Born at Elective CS
Children born after elective C-section have a greater risk of respiratory problems and hypoglycemia - most likely due to a lower concentration of stress hormones compared to children born vaginally.
- Trial name
- NCT00322660
- Testing
- Adrenaline
- Where
- 2 sites in Denmark
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Chronic Obstructive Pulmonary Disease
Postural Drainage With and Without Percussion in Chronic Obstructive Pulmonary Disease
Effects Of postural drainage with and without percussion on mucus clearance, dyspnea and quality of life in Chronic Obstructive Pulmonary disease. 34 Patients will be explained in detail about the procedure under study.
- Trial name
- NCT05649423
- Testing
- POSTURAL DRAINAGE WITH PERCUSSION, Postural drainage
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Dyspnea
Prehospital Triage of Patients With Severe Shortness of Breath Using Biomarkers
Breathlessness is a dangerous symptom. Preliminary data from national and regional Danish databases show, that patients with shortness of breath in the ambulance have a very high mortality.
- Trial name
- PreBNP (NCT02050282)
- Testing
- Supplementary NT-proBNP measurement
- Where
- 9 sites in Denmark
- Volunteers
- 712 people
- Sponsor
- University of Aarhus
Pulmonary Disease, Chronic Obstructive
Effect of Tiotropium + Olodaterol on Breathlessness in COPD Patients
The primary objective of the present study is to evaluate the effect of tiotropium + olodaterol fixed dose combination (FDC) compared to tiotropium monotherapy on the intensity of breathlessness during the 3min constant speed…
- Trial name
- NCT02853123
- Testing
- Tiotropium, Olodaterol
- Where
- 13 sites in Belgium, Canada and 2 more
- Volunteers
- 106 people
- Sponsor
- Boehringer Ingelheim
Covid19, Sars-CoV-2 Infection
Post Acute Sequelae of COVID-19
COVID-19, a novel coronavirus, has caused widespread mortality and morbidity since it emerged in 2019. There is ongoing research and growing literature describing severe acute respiratory syndrome (SARS-COV-2).
- Conditions
- Covid19, Sars-CoV-2 Infection, Dyspnea Caused by 2019-nCoV, COVID-19 Acute Respiratory Distress Syndrome
- Trial name
- PASC (NCT04964115)
- Testing
- Cohort study
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Vanderbilt University Medical Center
COVID-19
Pulmonary Rehabilitation in Post-Acute Period of COVID-19 Infection
The aim of this study is to investigate the efficacy of pulmonary rehabilitation(PR) applied in the isolation processes of post-acute patients with mild and moderate symptoms who had positive COVID-19 test on dyspnea,muscle…
- Trial name
- NCT04365738
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Istanbul Bilgi University