Clinical trials: Dyspnoea
Dyspnea
Prognostic Value of Pulse Oximetry Differences
This prospective observational study aims to evaluate whether the difference between finger, earlobe and forehead SpO₂ (ΔSpO₂) measured at emergency department (ED) presentation is associated with clinical outcomes in adult…
- Trial name
- NCT07824414
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Yonsei University
Dyspnea Caused by 2019-nCoV
Bevacizumab in Post-acute Sequelae of COVID-19 : Efficacy and Safety (Pilot Study)
The aim of this research is to evaluate an innovative treatment, Bevacizumab, in patients suffering from respiratory complications related to COVID-19.
- Trial name
- BASECOVID (NCT07089719)
- Testing
- Bevacizumab Injection
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Asthma
A Long-term Safety Study of QMF149 in Japanese Participants With Asthma
The purpose of this study was to provide long term safety data of QMF149 in Japanese participants with inadequately controlled asthma for the registration of QMF149 in Japan.
- Trial name
- NCT03100500
- Testing
- QMF149
- Where
- 15 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Novartis Pharmaceuticals
Dyspnea, Hypoxia
Diaphragmatic Paralysis in Arthroscopic Shoulder Surgery
This study aims to assess consequences and causes of hemidiaphragmatic paralysis for ambulatory arthroscopic shoulder surgery in patients with BMI ≥ 30 kg/m².
- Conditions
- Dyspnea, Hypoxia, Analgesia
- Trial name
- NCT03192865
- Testing
- diaphragmatic assessment using ultrasounds.
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Clinique Medipole Garonne
Pulmonary Disease, Chronic Obstructive (COPD), Dyspnea
Asymmetric High-Flow Nasal Cannula During Pulmonary Rehabilitation in COPD
This randomized pilot trial evaluated the feasibility and preliminary effects of using asymmetric high-flow nasal cannula (A-HFNC) during exercise-based pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary…
- Conditions
- Pulmonary Disease, Chronic Obstructive (COPD), Dyspnea, Exercise Tolerance, Rehabilitation
- Trial name
- A-HFNC-PR (NCT07497230)
- Testing
- Asymmetric High-Flow Nasal Cannula (A-HFNC), Conventional Pulmonary Rehabilitation Program
- Where
- Chile
- Volunteers
- 30 people
- Sponsor
- Universidad de Santiago de Chile
Cystic Fibrosis, Parents
Development,Validity and Reliability of a Caregiver Version of the Breathlessness Beliefs Questionnaire
The goal of this methodological study is to determine the reliability and validity of the The Breathlessness Beliefs Questionnaire Caregiver Version (BBQ-C) version in assessing dysfunctional breathlessness beliefs in caregivers…
- Trial name
- NCT06289972
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Halic University
Pulmonary Disease, Chronic Obstructive
Fluticasone Propionate/Salmeterol Combination 250/50 DISKUS in the Exercise Endurance Time in Patients With Chronic Obstructive Pulmonary Disease
The objective of this study is to demonstrate that, when added to tiotropium (TIO), fluticasone propionate/salmeterol combination (FSC) DISKUS 250/50 significantly increases exercise endurance time (EET) in the endurance shuttle…
- Trial name
- ESWT (NCT01124422)
- Testing
- fluticasone propionate/salmeterol inhalation powder DISKUS 250/50, tiotropium bromide inhalation powder HandiHaler
- Where
- 27 sites in United States, Canada
- Volunteers
- 255 people
- Sponsor
- GlaxoSmithKline
COPD
Effect of Different Form of Upper Limb Muscles Training on Dyspnea in COPD
Evaluate the effect of upper limbs strength training versus the effect of upper limbs endurance training, on dyspnea, in patients with COPD during a pulmonary rehabilitation program.
- Trial name
- REHABSUP (NCT03611036)
- Testing
- Strength training, Endurance training
- Where
- 2 sites in France
- Volunteers
- 280 people
- Sponsor
- University Hospital, Brest
Acute Respiratory Failure
High Flow During Weaning From Mechanical Ventilation
Detection and relief of dyspnea in mechanically ventilated patients is a priority. Optimization of mechanical ventilation settings is unfortunately often insufficient to relieve dyspnea in patients entering the weaning process.
- Trial name
- FLOWEAN (NCT05577221)
- Testing
- High Flow Nasal Air
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Pulmonary Disease
Effect of Bronchodilation on Cycle vs Treadmill Exercise Endurance Time in COPD
Previous studies suggest that treadmill exercise may be a more relevant exercise stimulus than the cycle ergometer to demonstrate benefits with bronchodilator therapy in patients with COPD.
- Trial name
- ARFEET (NCT00754546)
- Testing
- Arformoterol tartrate, Treadmill Exercise, Cycle Exercise
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Main Heading (Descriptor) Terms
Impact of Kolcaba Comfort Theory Training on Dyspnea, Function, and Comfort in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is the third most fatal chronic disease worldwide, following cardiovascular diseases and cancer.
- Trial name
- NCT06588361
- Testing
- Training Based on Kolcoba Comfort Theory
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
COVID-19
Long-Term Respiratory Muscle Strength in Young COVID-19 Patients
The coronavirus disease 2019 (COVID-19) is a highly contagious disorder caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Trial name
- NCT05381714
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Shortness of Breath/Dyspnea
Open Trial of Biofeedback for Respiratory Symptoms
Biofeedback is a therapeutic paradigm that teaches patients how to gain awareness and control over previously unrecognized sympathetic changes such as body temperature, blood pressure, and heart rate.
- Trial name
- NCT05973513
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Los Angeles
Tuberculosis
Effects of the Active Cycle of Breathing Technique With and Without Balloon Blowing Therapy in Tuberculosis
The study design will be a randomized controlled trial. The data will be collected from Gulab Devi Teaching Hospital, Lahore. 34 kids aged 8 to 14 years will be randomly assigned either to an experimental group or a control…
- Trial name
- NCT07484490
- Testing
- Active cycle of breathing with Balloon therapy, Active Cycle of breathing
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Cystic Fibrosis (CF), Cystic Fibrosis in Children
Physical Impairments in Children With Cystic Fibrosis
It is aimed to reveal impairments regarding urinary incontinence, dyspnea, muscle strength, functional capacity or quality of life in children and adolescents with cystic fibrosis compared to healthy children and adolescents.
- Trial name
- NCT06984679
- Testing
- Physical Evaluations in Children with Cystic Fibrosis, Physical Evaluations in Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir Democracy University
Asthma, Asthma (Diagnosis)
Intercostal and Thoracic Cage Stretching on Chest Expansion , Dyspnea ,Oxygen Saturation in Asthma
The rationale of this study is to clarify distinct role of these two stretching techniques in pulmonary rehabilitation. Insight gained from this research could provide evidence based recommendations for implementing these…
- Trial name
- NCT07331662
- Testing
- thoracic cage stretching, intercostal stretching
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Heart Failure With Preserved Ejection Fraction, Obesity
Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF
The overall purpose of this study is to investigate whether pulmonary limitations that increase the oxygen (O2) cost of breathing impact dyspnea on exertion (DOE) and peak exercise capacity in patients with HFpEF and obesity.
- Trial name
- NCT05723679
- Testing
- HeO2 gas mixture, Room air gas mixture
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cancer
Progressive Relaxation Exercise on Dyspnea, Pain and Sleep Quality
This study was planned to examine the effect of progressive relaxation exercises applied to lung cancer patients receiving chemotherapy on dyspnea, pain and sleep quality.
- Trial name
- Progressive (NCT04978805)
- Testing
- Progressive Relaxation Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Sabahattin Zaim University
Asthma
Effects of Balloon-blowing Exercises in 90/90 Bridge Position With a Ball on Pulmonary Function Among Asthmatic Patients
In asthma, the airways in the respiratory system can experience inflammation and constriction, causing increased difficulty in expelling air during exhalation.
- Trial name
- NCT06660537
- Testing
- Balloon-blowing exercises in 90/90 bridge position with a ball., Buteyko breathing exercises management
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- Foundation University Islamabad
Heart Diseases
Pain Assessment, Incidence & Nature in Heart Failure
Heart failure, a chronic illness afflicting 5 million persons in the United States is known to cause shortness of breath and fatigue, yet at least half of persons with heart failure also report the presence of pain.
- Trial name
- PAIN-HF (NCT00444301)
- Where
- 14 sites in United States
- Volunteers
- 349 people
- Sponsor
- PC-HEART
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