Clinical trials: Dyspnoea
Breathlessness, Cardiovascular
"Breathlessness Diagnostics in a Box" (BiaB) for Primary Care. A Multi-country Quality Improvement Project Using a Randomized Stepped-wedge Design
This prospective stepped-wedge study evaluates whether use of the Breathlessness diagnostics in a Box (BiaB) tool shortens the time to diagnosis in patients presenting with breathlessness, compared with usual care.
- Conditions
- Breathlessness, Cardiovascular, Pulmonary, Mental Disease
- Trial name
- BiaB (NCT07320703)
- Testing
- Breathlessness diagnostics in a Box (BiaB)
- Where
- 3 sites in Netherlands, Portugal and 1 more
- Volunteers
- 900 people
- Sponsor
- General Practitioners Research Institute
Asthma (Diagnosis) With Forward Head Posture
Comparative Effects of Posture Correction Exercises and Papworth Technique in Asthmatic Forward Head Posture
This study aims to evaluating and contrasting the effects of posture correction and papworth technique on dyspnea, chest expansion and quality of life in asthmatic patients with forward head.
- Trial name
- NCT07573904
- Testing
- papworth teachnique, posture correction exercises
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
COPD, ILD
SWEEP: Shuttle Walking Test for Exercise Evaluation in Pulmonary Resection
This is a prospective observational study that evaluates whether the Shuttle Walking Test (SWT) can predict postoperative symptoms, particularly dyspnea, in patients with chronic respiratory diseases undergoing lung resection.
- Conditions
- COPD, ILD, Bronchiectasis, Lung Cancer NOS
- Trial name
- SWEEP (NCT07102589)
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Bundang Hospital
COVID-19, Post-Acute COVID-19 Syndrome
Study on Post-Acute COVID-19 Syndrome in Improvement of COVID-19 Rehabilitated Patients by Respiratory Training
Since the emergence of Corona Virus Disease 2019(COVID-19), it has spread rapidly around the world, And it has had a profound impact on the lives and health of people around the world, most of the COVID-19 positive patients are…
- Conditions
- COVID-19, Post-Acute COVID-19 Syndrome, Dyspnea, Incentive Spirometer
- Trial name
- NCT06165835
- Testing
- breathing training
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
COPD, Cancer
SELF - BREATHE for Chronic Breathlessness
Semi-structured qualitative interviews will be conducted to understand key factors that would enable / facilitate patients with chronic breathlessness to potentially use an online breathlessness intervention (SELF-BREATHE).
- Conditions
- COPD, Cancer, Heart Failure, Interstitial Disease
- Trial name
- NCT04466020
- Testing
- Qualitative research interviews to be conducted
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- King's College Hospital NHS Trust
Systemic Sclerosis, Shortness of Breath
Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With Ambrisentan
The purpose of this study is to determine the clinical characteristics and hemodynamic profiles that predict exercise induced pulmonary hypertension in 15 patients with systemic sclerosis.
- Conditions
- Systemic Sclerosis, Shortness of Breath, Pulmonary Hypertension
- Trial name
- NCT01051960
- Testing
- Ambrisentan
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, Los Angeles
COVID-19
Functional Capacity in Patients Post Mild COVID-19
Patients recovered from mild coronavirus 2019 (COVID-19) disease without pulmonary involvement may experience long-term physical impairment and dyspnea.
- Trial name
- NCT05323760
- Testing
- Cardiopulmonary exercise test (CPET)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Heart Failure, Congestive, Dyspnea
Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF
Heart failure (HF) is a disease that is caused by a reduced heart muscle function. Reduced heart muscle function can occur as a consequence of reduced pumping activity from a weak heart muscle or because of a stiff heart muscle.
- Conditions
- Heart Failure, Congestive, Dyspnea, Pulmonary Edema
- Trial name
- NCT00505791
- Testing
- Nesiritide
- Where
- United States
- Sponsor
- University of Medicine and Dentistry of New Jersey
Pulmonary Embolism, Dyspnea
Ventilation/Perfusion PET/CT With Galligas and 68Ga-MAA for Regional Lung Function Assessment After Pulmonary Embolism
In patients with pulmonary embolism (PE), after three or six months of anticoagulation, persistent dyspnea and impairment of quality of life are observed in at least 30% of cases.
- Trial name
- EOLE (NCT05103670)
- Testing
- Ventilation/Perfusion PET/CT with Galligas and 68Ga-MAA
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Brest
Dyspnea, Coronary Artery Disease
Dyspnea in Stable Patients With Coronary Artery Disease.
Single-centre prospective study to characterize causes of dyspnea in stable patients with coronary artery disease and evaluate the possibility to determine the cause of dyspnea before in-depth examination.
- Trial name
- NCT04408612
- Testing
- Scales for assessment of symptoms
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- National Research Center for Preventive Medicine
Interstitial Lung Disease, Scleroderma
Effects of Whole Body Vibration Training in Patients With Interstitial Lung Disease
Interstitial lung disease (ILD) is a diverse group of parenchymal lung disorders characterized by restrictive lung function and impaired alveolar diffusion capacity, leading to dyspnea on exertion, reduced exercise endurance, and…
- Conditions
- Interstitial Lung Disease, Scleroderma, Idiopathic Pulmonary Fibrosis
- Trial name
- NCT03560154
- Testing
- Whole Body Vibration Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Heart Failure, Cardiovascular Disease
Use of Nesiritide in the Management of Acute Diastolic Heart Failure
Primary objective is to assess the effect of nesiritide in decreasing left ventricular (LV) filling pressure, defined as pulmonary artery capillary wedge pressure (PCWP) in a group of patients admitted with acute diastolic heart…
- Conditions
- Heart Failure, Cardiovascular Disease, Acute Heart Failure, Diastolic Heart Failure
- Trial name
- NCT00083772
- Testing
- Nesiritide
- Volunteers
- 9 people
- Sponsor
- M.D. Anderson Cancer Center
Lung Transplantation, Pulmonary Rehabilitation
Relation Between Muscle Strength With Exercise Capacity and Dyspnea in LTx
Severe exercise intolerance and shortness of breath are present in lung transplant candidates. Clinical features that reveal these symptoms in terminal period lung patients vary and are unclear.
- Trial name
- NCT03668483
- Testing
- Pulmonary rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Istanbul Medipol University Hospital
Pulmonary Disease, Chronic Obstructive
PEP Buddy Impact on Breathing, Exercise, and Sleep Quality in COPD Patients
Exercise intolerance and sleeping problems are among the most common symptoms experienced by patients with chronic obstructive pulmonary disease (COPD), which is associated with lung dynamic hyperinflation (DH).
- Trial name
- NCT06290245
- Testing
- PEP Buddy, aerobic exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Post-Acute COVID-19, Post-Acute COVID-19 Syndrome
Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID-19 Syndrome: A Randomized Controlled Trial
About 10-20% of persons who contract SARS CoV-2 will experience persistent post-acute sequelae of SARSCoV-2 infection (referred here as PASC).
- Conditions
- Post-Acute COVID-19, Post-Acute COVID-19 Syndrome, Post-Acute COVID-19 Infection, Long COVID
- Trial name
- NCT06156202
- Testing
- Comprehensive Rehabilitation, Augmented Usual Care
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Pennsylvania
Dyspnea
Systolic Time Intervals in the Diagnosis of Heart Failure in Emergency Departement
the gold standard for the diagnostic of acute heart failure is based on clinical, biological (BNP levels) and echocardiographic findings, but still in some cases, the diagnosis is difficult and requires further investigations.
- Trial name
- STA/AHF (NCT02161445)
- Testing
- the acoustic cardiographic parameters were calculated
- Where
- Tunisia
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- University of Monastir
COPD
Effect of a New Combination Bronchodilator on Exercise in GOLD Stage II Moderate COPD
Preliminary information from our laboratory indicated that even patients with milder chronic obstructive pulmonary disease (COPD) can have significant physiological derangements which become more pronounced during exercise…
- Trial name
- NCT01491802
- Testing
- LAMA/LABA, LAMA
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Queen's University
Dyspnea, Chronic Obstructive Pulmonary Disease
The Impact of Udenafil on Exercise Capacity in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients
Pulmonary hypertension (PH) is a serious complication of COPD which is associated with shorter survival, more frequent exacerbation, and increased use of health resources.
- Conditions
- Dyspnea, Chronic Obstructive Pulmonary Disease, Pulmonary Hypertension
- Trial name
- NCT01364181
- Testing
- Udenafil
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Seoul National University Hospital
Sleep Apnea
Sleep Apnea. Concordance Between Non-reference and Reference Centres
When a disorder is as prevalent as sleep apnea hypopnea syndrome various medical levels and strategies should be implicated. We to evaluate the degree of concordance in management between a sleep reference centre and…
- Trial name
- NCT00424658
- Testing
- SAHS diagnosis
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Hospital Clinic of Barcelona
Dyspnea, Cough
Respiratory Complaints Checklist Trial
This is a randomized clinical trial that evaluates the impact of using an internet-based checklist for systematic assessment of patients reporting respiratory complaints with the conventional assessment, without using the…
- Trial name
- RCC (NCT02283892)
- Testing
- Checklist, Conventional evaluation
- Where
- Brazil
- Volunteers
- 39 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
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