Clinical trials: Dyspnoea
Interstitial Lung Disease (ILD)
Nasal High-flow Oxygen Therapy During Acute Exercise in Fibrotic Interstitial Lung Disease
Hallmarks of fibrotic interstitial lung disease (f-ILD) include severe hypoxemia, dyspnea and exercise limitation. Although ambulatory oxygen (O2) therapy is widely prescribed, standard low-flow O2 systems (nasal prongs) fail to…
- Trial name
- PID-OXacute (NCT07129707)
- Testing
- Exercise testing
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Dieulefit Santé Centre de Réadaptation
Emphysema
Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease
The purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.
- Trial name
- NCT00034112
- Testing
- osteopathic manipulative treatment
- Where
- United States
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Covid19, Dyspnea
Follow-up of Respiratory Sequelae of Hospitalized Patients With COVID-19
The objective of this multicenter observational study is to describe respiratory sequelae of COVID-19 patients hospitalized for severe pneumonia requiring oxygen supply.
- Trial name
- SISCOVID (NCT04505631)
- Where
- 14 sites in France
- Volunteers
- 332 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Chronic Obstructive Pulmonary Disease (COPD), Neuromuscular Electrical Stimulation (NMES)
Effect of Neuromuscular Electrical Stimulation of Lower Limbs on Improving Exercise Self-Efficacy, Dyspnea During Activity and Fatigue in Patients With Chronic Obstructive Pulmonary Disease
Patients diagnosed with COPD who meet the inclusion and exclusion criteria, either inpatients or outpatients, will be informed about the study'sstudy's purpose and procedures by the principal investigator.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Neuromuscular Electrical Stimulation (NMES), Exercise Self-Efficacy, Dyspnea During Activity
- Trial name
- NMES (NCT06851195)
- Testing
- lower limb neuromuscular electrical stimulation, pulmonary rehabilitation exercises
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Asthma
Effects of Abdominal Binder on Dysnea, Control Pause and Quality of Life in Asthmatic Patients
This study investigates the effects of using an abdominal binder as an adjunct to diaphragmatic breathing in asthma patients. The goal is to determine if the binder improves respiratory mechanics, specifically reducing dyspnea…
- Trial name
- NCT07612384
- Testing
- Abdominal binder -assisted diaphragmatic breathing, Conventional diaphragmatic breathing exercise
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Foundation University Islamabad
COPD
Effect of Different Form of Upper Limb Muscles Training on Dyspnea in COPD
Evaluate the effect of upper limbs strength training versus the effect of upper limbs endurance training, on dyspnea, in patients with COPD during a pulmonary rehabilitation program.
- Trial name
- REHABSUP (NCT03611036)
- Testing
- Strength training, Endurance training
- Where
- 2 sites in France
- Volunteers
- 280 people
- Sponsor
- University Hospital, Brest
Dyspnea, Heart Failure Acute
Evaluation of the Effectiveness of the CardioStory Device in Distinguishing Heart Failure From Other Causes in Patients Presenting With Dyspnea
The CARDIOSTORY.TN study is a prospective observational study at Sahloul University Hospital (Sousse, Tunisia) evaluating the CardioStory device for distinguishing heart failure (HF) from other causes of acute dyspnea.
- Trial name
- CARDIOSTORY (NCT07147699)
- Testing
- cardiostory
- Sponsor
- Hôpital Universitaire Sahloul
Coma, Major Trauma
Succinylcholine vs Rocuronium for Prehospital Emergency Intubation
All adult patients with spontaneous cardiac activity and requiring tracheal intubation in the pre hospital emergency context will be included in order to compare the use of succinylcholine vs Rocuronium for prehospital emergency…
- Conditions
- Coma, Major Trauma, Respiratory Distress, Shock
- Trial name
- CURASMUR (NCT02000674)
- Testing
- Succinylcholine : 1mg/kg, Rocuronium : 1.2 mg/kg
- Where
- 17 sites in France
- Volunteers
- 1,321 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Heart Failure, COPD
Ultrasound in Acute Dyspnea in the Field
Acute heart failure is one of the main causes of acute respiratory distres in prehospital emergency setting. The early and correct diagnosis is important because the misdiagnosis can result in deleterious consequeance to…
- Conditions
- Heart Failure, COPD, Asthma
- Trial name
- NCT01235182
- Where
- Slovenia
- Volunteers
- 248 people
- Sponsor
- University Medical Centre Maribor
COPD
Continuous Chest Wall Vibration in COPD Rehabilitation
Dyspnea, the sensation of breathing discomfort or shortness of breath, is one of the main symptoms for patients affected by Chronic Obstructive Pulmonary Disease (COPD), particularly during exercise.
- Trial name
- NCT03644888
- Testing
- Cycle ergometer training, Airway clearance program, Vibration therapy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Lung Cancer, Dyspnea
Acupuncture Feasibility Trial for Dyspnea in Lung Cancer
This is a single arm clinical trial to establish the feasibility of conducting a clinical trial of acupuncture in reducing dyspnea among lung cancer survivors who have completed chemoradiotherapy.
- Trial name
- NCT02094950
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Chronic Bronchitis
Early Mobilization With and Without Chest Physiotherapy in Chronic Bronchitis Patients.
It will be a randomized control trial study in which data are collected from hospital. A sample of 26 patients will divided into two group.
- Trial name
- NCT05646225
- Testing
- chest physiotherapy and early mobilization, early mobilization
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Wheezy Bronchitis, Asthmatic Bronchitis
Efficacy of Intermittent Tiotropium in Early Childhood Wheezing
This study evaluates the effect of intermittent tiotropium bromide and salbutamol as needed versus intermittent fluticasone propionate and salbutamol as needed, or solely, salbutamol as needed on episode-free days in infants and…
- Conditions
- Wheezy Bronchitis, Asthmatic Bronchitis, Wheezing, Obstruction Airway
- Trial name
- NCT03199976
- Testing
- Tiotropium Bromide, Fluticasone Propionate, Salbutamol
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Chronic Obstructive Pulmonary Disease (COPD)
The Effect of Walking Exercise in Patients With Chronic Obstructive Pulmonary Disease
"Patients were divided into two groups: the experimental group (E group) and the control group (C group). The E group received standard care, walking exercise, and elastic band exercise, and wore a smart bracelet to record…
- Trial name
- COPD (NCT07185659)
- Testing
- Elastic band, Xiaomi Mi Band 4 wearable device, Walking
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
COPD, Dyspnea
Deventilation Dyspnea in COPD Patients Using NIV
Non-invasive ventilation (NIV) has shown to be an effective therapy for patients with Chronic Obstructive Pulmonary Disease (COPD) with Chronic Hypercapnic Respiratory Failure (CHRF).
- Conditions
- COPD, Dyspnea, Mechanical Ventilation Complication
- Trial name
- NCT03503123
- Testing
- Monitoring physiology with Electrical Impedance Tomography, Electromyography and transcutaneous carbon dioxide measurements.
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
COPD, Asthma
Participatory Action Research to Evaluate the Delivery of the MISSION ABC Service Model and Assess Health Service and Clinical Outcomes
Innovations aimed at improving new patient identification, diagnosis, nonpharmacological treatment, supported self-management, and remote monitoring, together with new methods of clinical support could improve outcomes in…
- Conditions
- COPD, Asthma, Breathlessness
- Trial name
- NCT03096509
- Testing
- MISSION ABC Integrated Care clinic
- Where
- United Kingdom
- Volunteers
- 342 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Dyspnea
Diagnostic Performance of Chest Computed Tomography Scan in Patients Aged 65 and Over Presenting to Emergency Room With Acute Dyspnea
In acute dyspnea, the use of chest radiography is frequent and not very contributive, especially in the elderly patients. However, early diagnosis of the cause of dyspnea in the ED is associated with a better prognosis, in…
- Trial name
- CT-Dys (NCT06104475)
- Testing
- CT scan
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dyspnea, Congestive Heart Failure
The Use of Intranasal Fentanyl for the Treatment of Incident Dyspnea in Congestive Heart Failure: A Prospective Trial
Study Objective The primary object of this study is to investigate the safety and effectiveness of fentanyl on the management of incident dyspnea.
- Trial name
- NCT02454751
- Testing
- fentanyl
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- St. Boniface Hospital
Hypertrophic Cardiomyopathy
Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy
The primary objective of this study was to evaluate the effect of eleclazine (GS-6615) on exercise capacity as measured by Peak oxygen uptake (VO2) achieved during cardiopulmonary exercise testing (CPET), in participants with…
- Trial name
- LIBERTY-HCM (NCT02291237)
- Testing
- Eleclazine
- Where
- 46 sites in United States, Australia and 6 more
- Volunteers
- 172 people
- Sponsor
- Gilead Sciences
COPD, Inspiratory Muscle Training
Effectiveness of IMT/PEP Therapy in Group E COPD and Comparison of GOLD vs STAR Classifications
Background: Inspiratory muscle training combined with positive expiratory pressure (IMT/PEP) may improve outcomes in chronic obstructive pulmonary disease (COPD), but evidence in exacerbation-prone (Group E) disease is limited.
- Trial name
- NCT07001462
- Testing
- Inspiratory Muscle Training / Positive Expiratory Pressure (IMT/PEP) Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Bugra Kerget
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