Clinical trials: Dyspnoea
Respiratory Insufficiency
B-type Natriuretic Peptide (BNP)-Guided Diagnostic Strategy in Intensive Care Unit (ICU) Patients With Respiratory Failure
Heart failure is a common reason for respiratory failure in ICU patients. The rapid and accurate differentiation of heart failure from other causes of respiratory failure remains a clinical challenge.
- Trial name
- NCT00130559
- Testing
- BNP guided diagnostics and initial therapy
- Where
- 6 sites in Switzerland
- Volunteers
- 286 people
- Sponsor
- University Hospital, Basel, Switzerland
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial
Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest
This study is meant to compare the amount of oxygen required for hypoxemia relief between current standard of care (oxygen only) and oxygen with the addition of high flow air for Chronic Obstructive Pulmonary Disease (COPD)…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Interstitial, Pulmonary Fibrosis, Hypoxemia
- Trial name
- NCT04170062
- Testing
- Nasal Delivery of High-Flow Air and Oxygen Therapy, Nasal Delivery of Oxygen Therapy
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Johns Hopkins University
Chronic Obstructive Pulmonary Disease
The Role of Substance P on Perception of Breathlessness During Resistive Load Breathing
Substance P is released from sensory nerves and transmits pain information into the central nervous system. As pain and dyspnea share many characteristics, including similar neurological pathways, it is possible that substance P…
- Trial name
- SP-RLB (NCT01580423)
- Testing
- aprepitant
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Inhalation Therapy; Complications
The Effect of Stress Ball Utilisation on Treatment Duration, Dyspnea Severity and Anxiety Level in Nebuliser Therapy
Nebul Therapy is very effective in quickly improving the symptoms of respiratory system diseases. While applying this treatment, patients are expected to complete a sufficient period of time.
- Trial name
- NCT06297356
- Testing
- Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
COPD
The Effect of Face Hand Fan Application on Dyspnea
Diagnosing and managing dyspnea in patients with COPD is very important. Although pharmacological and non-pharmacological methods are used in the management of dyspnea, it is recommended that pharmacological methods be supported…
- Trial name
- HandfanCOPD (NCT06265831)
- Testing
- Hand-fan application to the face
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Bartın Unıversity
Respiratory Distress Syndrome, Newborn
Thoracic Fluid Content by Electric Bioimpedance Versus Lung Ultrasound in Preterm Neonates With Respiratory Distress
A prospective cohort study aims to evaluate the predictive value of thoracic fluid content measured by electric bioimpedance for detecting the need for surfactant administration or positive pressure ventilation requirement…
- Trial name
- NCT05594030
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Lung; Disease, Cystic Fibrosis
Orkambi Exercise Study
Shortness of breath (dyspnea) during exercise is a major source of distress and is a commonly reported symptom in patients with cystic fibrosis (CF).
- Trial name
- Orkambi (NCT02821130)
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of British Columbia
Dyspnea, Pain
Effectiveness of I COUGH Program to Dyspnea, Respiratory Parameters, Mobility and Pain After Major Abdominal Surgery
The purpose of the current study was to investigate the effect of the I COUGH care program following major abdominal surgery dyspnea, oxygen saturation, pulmonary function, mobility, and pain after major abdominal surgery (MAS)…
- Conditions
- Dyspnea, Pain, Respiratory Insufficiency, Mobility Limitation
- Trial name
- NCT06255327
- Testing
- I COUGH care program
- Where
- 3 sites in Libya
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Lung Cancer
The Effect of Mindfulness-Based Breathing Exercises on Dyspnea, Symptom Control, and Quality of Life in Lung Cancer Patients Undergoing Chemotherapy
This research is designed to determine the effect of mindfulness-based breathing exercises on dyspnea, symptom control, and quality of life in lung cancer patients undergoing chemotherapy.
- Trial name
- NCT07520799
- Testing
- Mindfulness-Based Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Firat University
Acute Respiratory Failure
Low Dose Morphine to Relieve Dyspnea in Acute Respiratory Failure (OPIDYS)
This study evaluates a pharmacological intervention to relieve dyspnea in intensive care unit patients. Indeed, opioids can be particularly beneficial since 1) dyspnea and pain share many similarities, 2) the benefit of opioids…
- Trial name
- OPIDYS (NCT04358133)
- Testing
- Chlorhydrate de morphine, NaCl 0,9%,
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Smog-Induced Pneumonia, Pneumonia
Effects of Buteyko Breathing Versus Incentive Spirometry on Oxygen Saturation, Dyspnoea, Exercise Tolerance, and Sputum Clearance in Patients With Smog Induced Pneumonia
The current study will be a single-blind, parallel-group randomized controlled trial involving 62 patients diagnosed with smog-induced pneumonia.
- Trial name
- NCT07759583
- Testing
- Buteyko Breathing Technique (BBT), Incentive Spirometry (IS)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Lahore University of Biological and Applied Sciences
COPD, Heart Failure, Congestive
Clinical Assessment of Patients With Chronic Obstructive Pulmonary Disease (COPD) and/or Chronic Heart Failure (CHF)
Cigarette smoking, the major risk factor for COPD, causes not only airway and lung inflammation, but also systemic effects. These systemic effects of smoking could substantially contribute to the development of chronic diseases…
- Trial name
- NCT01114386
- Testing
- Lung function testing, echocardiography, blood sampling
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Interstitial Lung Disease, Scleroderma
Effects of Whole Body Vibration Training in Patients With Interstitial Lung Disease
Interstitial lung disease (ILD) is a diverse group of parenchymal lung disorders characterized by restrictive lung function and impaired alveolar diffusion capacity, leading to dyspnea on exertion, reduced exercise endurance, and…
- Conditions
- Interstitial Lung Disease, Scleroderma, Idiopathic Pulmonary Fibrosis
- Trial name
- NCT03560154
- Testing
- Whole Body Vibration Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Coronavirus Infection
Describing Chinese Herbal Medicine Telehealth Care for Symptoms Related to Infectious Diseases Such as COVID-19
The purpose of the study is to design and execute a prospective, longitudinal, descriptive cohort study in a pragmatic clinical practice for adults with symptoms that may be related to COVID-19.
- Trial name
- NCT04380870
- Testing
- Chinese Herbal Medicine
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Center for Integrated Care
Dyspnea, Respiratory Distress Syndrome
LUng and Cardiac Ultrasound for REspiratory Distress in ElDerly
Prospective trial to evaluate the impact on the initial therapeutic inadequacy of a management strategy for acute dyspnea in the elderly based on the use of lung and cardiac ultrasonography.
- Trial name
- LUCREED (NCT06807983)
- Testing
- diagnostic strategy based on lung and cardiac ultrasonography
- Where
- France
- Volunteers
- 504 people
- Sponsor
- University Hospital, Toulouse
Chronic Obstructive Pulmonary Disease, Arthritis
Modifying Exercise for the COPD Patient
This study will test whether using the Biodex BioStep Semi Recumbent Elliptical for the chronic obstructive pulmonary disease (COPD) patient with arthritic limitations will improve participation in a pulmonary rehab program…
- Conditions
- Chronic Obstructive Pulmonary Disease, Arthritis, Pain
- Trial name
- NCT02143206
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Angela N Fellner PhD CCRP
Post-Acute COVID19 Syndrome, Long COVID
Exercise Intervention Using mHealth in Patients With Post-Acute COVID-19 Syndrome: a Randomized Clinical Trial
Post-Acute Syndrome COVID-19 is a disease resulting from infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
- Conditions
- Post-Acute COVID19 Syndrome, Long COVID, Post COVID-19 Condition
- Trial name
- COVIDReApp (NCT05725538)
- Testing
- COVIDReApp Group, Control Group
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Cadiz
COPD, Chronic Bronchitis
The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis
Specific Aim: To determine the effectiveness of Roflumilast in improving i) whole right lung and ii) peripheral right lung mucociliary clearance (MCC) in patients with COPD and chronic bronchitis.
- Conditions
- COPD, Chronic Bronchitis, Emphysema
- Trial name
- NCT03073798
- Testing
- Roflumilast
- Volunteers
- 12 people
- Sponsor
- Johns Hopkins University
Chronic Obstructive Pulmonary Disease
Efficacy and Safety of Tulobuterol Patch Combined With Tiotropium Bromide for Relieving Dyspnea Symptom of Chronic Obstructive Pulmonary Disease
Phrase: IV Indication: dyspnea symptom of chronic obstructive pulmonary disease (COPD) Objective: to evaluate efficacy and safety of tulobuterol patch combined with Tiotropium bromide for relieving dyspnea symptom of COPD Design…
- Trial name
- NCT01465906
- Testing
- tulobuterol, Tiotropium Bromide
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Shanghai Zhongshan Hospital
ILD
Edmonton Dyspnea Inventory- Validation Study
Breathlessness is a common problem for many patients with Interstitial lung disease (ILD). ILD is a group of lung diseases that cause inflammation (swelling) and scarring in the lung tissue where gas exchange (oxygen and carbon…
- Trial name
- NCT06290635
- Testing
- Breathlessness Assessment Tool
- Where
- 3 sites in Canada, Denmark and 1 more
- Volunteers
- 79 people
- Sponsor
- University of Alberta
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