Clinical trials: Dyspnoea
Decompensated Heart Failure
Sensation of Dyspnea and Experience of Patients With Heart Failure
This randomized clinical trial aims to evaluate patients with decompensated heart failure undergoing an early mobilization protocol with the use of immersive virtual reality glasses compared with patients undergoing the same…
- Trial name
- MOVE (NCT05596292)
- Testing
- Immersive Virtual Reality glasses, early mobilization protocol
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Post-COVID19 Condition
Effect of Vitamin D Supplementation on Glutathione Peroxidase (GPx) Activity, Interleukin-6 (IL-6) Levels and Clinical Outcomes in Post-COVID-19 Patients
The goal of this clinical trial is to evaluate the effectiveness of vitamin D supplementation in treating neuropsychiatric symptoms and improving antioxidant levels in individuals diagnosed with post-COVID-19 condition, a state…
- Trial name
- VITDPOSTCOVID (NCT06419712)
- Testing
- vitamin D (cholecalciferol) supplementation
- Where
- Mexico
- Volunteers
- 54 people
- Sponsor
- Escuela Militar de Graduados de Sanidad, SEDENA
Progressive Muscle Relaxation, Deep Breath
Progressive Muscle Relaxation and Deep Breathing Exercises
The population of the study was composed of 186 patients whose cells were assigned to Atatürk University Hospital Educational Diseases Polyclinic between April and June 2023, and whose cells were found to have COPD according to…
- Conditions
- Progressive Muscle Relaxation, Deep Breath, COPD
- Trial name
- NCT05846204
- Testing
- Progressive Muscle Relaxation, Deep Breathing Exercise Group-DBE
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ataturk University
COVID-19
Pulmonary Rehabilitation in Post-Acute Period of COVID-19 Infection
The aim of this study is to investigate the efficacy of pulmonary rehabilitation(PR) applied in the isolation processes of post-acute patients with mild and moderate symptoms who had positive COVID-19 test on dyspnea,muscle…
- Trial name
- NCT04365738
- Testing
- Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people
- Sponsor
- Istanbul Bilgi University
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Pursed-Lip Breathing With Different I:E Ratios on Respiratory Outcomes in COPD Patients
The goal of this clinical trial is to evaluate whether different inspiratory-expiratory (I:E) ratios in the pursed-lip breathing (PLB) technique can improve respiratory outcomes in patients with stable Chronic Obstructive…
- Trial name
- PLB I:E Ratio (NCT07573826)
- Testing
- Participants perform PLB with inspiratory-expiratory ratio 1:3 (2 seconds inspiration, 6 seconds expiration), Participants perform PLB with inspiratory-expiratory ratio 1:4 (2 seconds inspiration, 8 seconds expiration), Participants perform PLB with inspiratory-expiratory ratio 1:5 (2 seconds inspiration, 10 seconds expiration)
- Volunteers
- 122 people
- Sponsor
- Scholastica Fina Aryu Puspasari
Lung Non-Small Cell Carcinoma, Lung Small Cell Carcinoma
Testing a Cognitive Behavioral Model for Reducing Dyspnea in Patients With Lung Cancer
This trial studies the effect of a form of cognitive-behavioral therapy, Take a Breath, on reducing the intensity and frequency of dyspnea (difficulty breathing) in patients with lung cancer.
- Trial name
- NCT05304793
- Testing
- Best Practice, Cognitive Behavior Therapy, Questionnaire Administration
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Chronic Obstructive Pulmonary Disease (COPD), Dyspnea
Evaluation of the Benefits of Hypnosis in Improving the Quality of Life of Patients With Chronic Obstructive Pulmonary Disease (COPD) Suffering From Persistent Dyspnea
Chronic Obstructive pulmonary Disease (COPD) is a common progressive disorder characterized by persistent airflow limitation. It is usually caused by exposure to tobacco smoke, toxic particles, or toxic gases.
- Trial name
- HYPNODYS (NCT07637604)
- Testing
- Hypnosis, standardized telephone calls
- Where
- France
- Volunteers
- 154 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dyspnea
Non-pharmacological Treatment of Dyspnea in Chronic Obstructive Pulmonary Disease (COPD)
Dyspnoea is one of the most important determinants of quality of life and often limits the activities of daily life, in subjects suffering from moderate-to-severe chronic obstructive pulmonary disease (COPD).
- Trial name
- COPD (NCT04231058)
- Testing
- TENS and pulmonary rehabilitation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Azienda USL Toscana Nord Ovest
COPD, Dyspnea
Pulmonary Rehabilitation, Dyspnoea and Emotional Cognition in COPD
To evaluate whether pulmonary rehabilitation improves emotional cognition, using facial emotions recognition and smile production, by improving the emotional dimension of dyspnoea in patients with chronic obstructive pulmonary…
- Conditions
- COPD, Dyspnea, Rehabilitation; Tobacco Use, Emotional Disturbances
- Trial name
- READ-COG BPCO (NCT03092700)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Hypoxia, Normobaric Hypoxia
Effect of Acute Hypoxia on RIght VEntRicular Function in Healthy Adults.
More and more people are engaging in sports in the mountains, including individuals with heart or lung diseases. At the same time, such diseases are becoming more common in Switzerland.
- Conditions
- Hypoxia, Normobaric Hypoxia, Altitude Hypoxia, Right Heart Function
- Trial name
- RIVER-H (NCT07431567)
- Testing
- Normobaric Hypoxia
- Where
- 2 sites in Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mona Lichtblau
Chronic Obstructive Pulmonary Disease Exacerbation, COPD Exacerbation
The Addition of Inhaled Furosemide to Standard Treatment of COPD Exacerbation
The goal of this randomized controlled trial is to determine the effect of adding inhaled furosemide to the known treatment of patient with Chronic obstructive pulmonary disease (COPD) exacerbation.
- Trial name
- FUROSCOPE (NCT05769738)
- Testing
- Furosemide, Normal saline
- Volunteers
- 200 people
- Sponsor
- American University of Beirut Medical Center
Dyspnea
Inhaled Ondansetron & Dyspnea
"Dyspnea" refers to the awareness of breathing discomfort that is typically experienced during exercise in health and disease. In various participant populations, dyspnea is a predictor of disability and death; and contributes to…
- Trial name
- NCT01851993
- Testing
- Ondansetron
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McGill University
Amyotrophic Lateral Sclerosis
Alleviating Persistent Dyspnea in Amyotrophic Lateral Sclerosis Patients Treated With Non-Invasive Ventilation Through Immersive Virtual Reality
The evolution of amyotrophic lateral sclerosis (ALS) is marked by dyspnea, anxiety and pain, major determinants of suffering induced by this disease.
- Trial name
- RVI-SLA (NCT06021938)
- Testing
- Immersive virtual reality (IVR) & Music therapy
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COPD
PEP-buddy in COPD: Effect on Dyspnea Severity and Mechanism of Action
Chronic dyspnea is the most characteristic symptom of patients with Chronic Obstructive Pulmonary Disease (COPD), with intermittent increases during exercise and other events.Despite optimal standard therapy, episodic dyspnea is…
- Trial name
- RELIEF (NCT05938738)
- Testing
- PEP-buddy
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- University Medical Center Groningen
Parkinson Disease
Neural Control of Breathing in Parkinson's Disease
Breathing is a complex process, which can be controlled through voluntary command or neural control. Parkinson's disease (PD) is a progressive neurological disorder.
- Trial name
- NEURON-PD (NCT06074614)
- Testing
- Hypercapnic ventilatory response, Respiratory related evoked potential, Transcranial magnetic stimulation
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
COVID
Study of the Safety of Therapeutic Tx With Immunomodulatory MSC in Adults With COVID-19 Infection Requiring Mechanical Ventilation
This is a phase 1b randomized, double-blind, placebo-controlled study in adult subjects with Coronavirus Disease 2019 (COVID-19).
- Trial name
- NCT04397796
- Testing
- BM-Allo.MSC
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- ImmunityBio, Inc.
Patients Undergoing Laparoscopic Inguinal Hernia Repair
The Effect of Cold Vapor on Dyspnea, Thirst, Nausea, and Physiological Parameters in the PACU After Laparoscopic Inguinal Hernia Surgery
Cold vapor application is considered a promising intervention with the potential to alleviate side effects associated with anesthesia and surgery in the postoperative period.
- Trial name
- NCT07273162
- Testing
- Cold Vapor
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- TC Erciyes University
Heart Failure, Exercise Tolerance (Measured in Minutes)
High-Flow Nasal Cannula on Exercise Tolerance in Heart Failure Patients Undergoing Cardiac Rehabilitation
The goal of this clinical trial is to learn if a high-flow nasal cannula (HFNC) - a device that delivers warm, humidified air through a small tube placed in the nostrils - can improve exercise tolerance in adults with heart…
- Conditions
- Heart Failure, Exercise Tolerance (Measured in Minutes), Cardiac Rehabilitation
- Trial name
- NCT07613762
- Testing
- High-Flow Nasal Cannula (HFNC)
- Where
- Chile
- Volunteers
- 28 people
- Sponsor
- Universidad de Santiago de Chile
Dyspnea
Point-of-care Ultrasound Interest in Dyspneic Emergency Department Patients: an Observational Bicentric Study
The diagnostic value of Point-of-care ultrasound (POCUS) in emergency department (ED) dyspneic patients is shown by numerous studies with a limited number of patients. Recently, Zanobetti et al.
- Trial name
- ECUDYS (NCT04327882)
- Testing
- Point-of-care ultrasound
- Where
- 2 sites in France
- Volunteers
- 2,600 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Main Heading (Descriptor) Terms
Impact of Kolcaba Comfort Theory Training on Dyspnea, Function, and Comfort in COPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is the third most fatal chronic disease worldwide, following cardiovascular diseases and cancer.
- Trial name
- NCT06588361
- Testing
- Training Based on Kolcoba Comfort Theory
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ataturk University
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