Clinical trials: Dyspnoea
Dyspnea, Peripheral Edema
NT-proBNP and New Biomarkers in Patients With Dyspnea and/or Peripheral Edema
The objectives of this study are to: Evaluate the sensitivity and specificity of NT-proBNP (N-terminal prohormone brain natriuretic peptide) and new biomarker measurements for the diagnosis of heart failure in patients with acute…
- Trial name
- MANPRO (NCT00143793)
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Universitätsmedizin Mannheim
Respiratory Distress Syndrome
Ventilatory Monitoring in Children With Respiratory Distress Syndrome With Electrical Impedance Tomography
INTRODUCTION: Electrical impedance tomography is a tool for noninvasive monitoring of pulmonary ventilation in real time, which is used during alveolar recruitment maneuvers in patients with acute respiratory distress syndrome.
- Trial name
- NCT03768921
- Testing
- PEEP Titriation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Metodista de Piracicaba
Cancer, Dyspnea
Effects of a Functional Re-education and Environmental Adaptation Programme in Cancer Patients With Associated Respiratory Pathology
the investigators propose an interdisciplinary intervention, carried out by occupational therapists, nurses, physiotherapists and doctors specialised in this type of patient, aimed at improving conventional clinical practice and…
- Conditions
- Cancer, Dyspnea, Functionality, Quality of Life
- Trial name
- NCT06035263
- Testing
- FUNCTIONAL REEDUCATION AND ENVIRONMENTAL ADAPTATION PROGRAMME, Health education programme:
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Salamanca
Shortness of Breath, Heart Failure
Biomarkers in Acute Heart Failure
Primary Objectives 1. Mid Region pro Adrenomedullin (MR-proADM) is superior to BNP for the prognosis of heart failure (HF) patients and adds incremental value in predicting outcomes for patients presenting to the Emergency…
- Trial name
- BACH (NCT00537628)
- Where
- 15 sites in United States, Germany and 6 more
- Volunteers
- 1,641 people
- Sponsor
- Brahms AG
Respiratory Rate
On the PhonE Respiratory rAte Study (OPERA)
Introduction. The increasing use of telephone medical advice requires the development of telemedicine tools to assess the patient's severity.
- Trial name
- OPERA (NCT04077593)
- Testing
- RRate Mobile app
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Grenoble
Dyspnea, Muscle Strain
Muscle Reflex Inhibition in Hypoxic Exercise
The goal of this interventional study is to compare muscle reflex function under settings of normoxia (normal oxygen level), acute hypoxia (brief oxygen-lack) and chronic hypoxia (long-duration exposure to oxygen-lack).
- Trial name
- NCT05619887
- Testing
- Fentanyl, Saline
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cystic Fibrosis (CF), Cystic Fibrosis in Children
Physical Impairments in Children With Cystic Fibrosis
It is aimed to reveal impairments regarding urinary incontinence, dyspnea, muscle strength, functional capacity or quality of life in children and adolescents with cystic fibrosis compared to healthy children and adolescents.
- Trial name
- NCT06984679
- Testing
- Physical Evaluations in Children with Cystic Fibrosis, Physical Evaluations in Healthy Children
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izmir Democracy University
Pulmonary Embolism
Pulmonary Rehabilitation to Improve Physical Capacity After Pulmonary Embolism
This project aims to evaluate a rehabilitation program as treatment and uncover potential pathophysiological mechanisms of a newly identified chronic condition named "Post Pulmonary Embolism Syndrome" (PPS).
- Trial name
- NCT03405480
- Testing
- Rehabilitation
- Where
- Norway
- Volunteers
- 209 people
- Sponsor
- Ostfold Hospital Trust
Dyspnea, Acute Heart Failure Syndrome
Precision of IMED-4 Lung Fluid Measurements
The purpose of this study is to determine if IMED-4 recordings have sufficient precision to detect a clinically significant change in lung fluid status in acute heart failure syndrome with pulmonary congestion.
- Conditions
- Dyspnea, Acute Heart Failure Syndrome, Pulmonary Congestion
- Trial name
- NCT02187770
- Testing
- IMED-4
- Where
- 3 sites in United States
- Volunteers
- 46 people
- Sponsor
- Intersection Medical, Inc.
Pulmonary Cancer
Multidisciplinary Rehabilitation After Cancer Pulmonis Operation
The purpose of this investigation is to determine the effects of exercise training on quality of life and physical capacity, 3 months and 1 year after radical operation for pulmonary cancer.
- Trial name
- NCT01048762
- Testing
- physical exercise and dyspnoea counseling, home training
- Where
- Denmark
- Volunteers
- 78 people
- Sponsor
- Aalborg University Hospital
Dyspnea
Aerosol Inhalation Treatment for Dyspnea - Patients
The purpose of this protocol is to develop and test aerosol furosemide, as a treatment that has the potential to significantly improve symptom management and enhance the quality of care for patients with intractable dyspnea.
- Trial name
- NCT02524054
- Testing
- Furosemide, Aerosolized saline
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Patients Hospitalized in the Hospices Civils of Lyon, COVID-19 Disease
Measurement of the Efficacy of MORPHINE in the Early Management of Dyspnea in COVID-19 Positive Patients
Morphine is used in the treatment of dyspnea and polypnea with a proven benefit on the improvement of these symptoms, both etiologically and symptomatically.
- Conditions
- Patients Hospitalized in the Hospices Civils of Lyon, COVID-19 Disease, Moderate to Severe Dyspnea, Without Resuscitation Objective Management
- Trial name
- CODYS (NCT04522037)
- Testing
- No intervention / Compare the difference in respiratory rate between H0 and H12 of the initiation of morphine between the control and interventional groups
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- Hospices Civils de Lyon
Asthma, COPD
Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient
An acute study carried out across three acute admissions units within Leicestershire. The study is aimed at discovery and validation of volatile organic compounds (VOCs) in exhaled breath.
- Conditions
- Asthma, COPD, Heart Failure, Community-acquired Pneumonia
- Trial name
- EMBER (NCT03672994)
- Where
- United Kingdom
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Leicester
COPD, Shortness of Breath
Comparison of Jacobson Relaxation Technique and Pranayama Technique in Patients With COPD
Comparison of Jacobson Relaxation Technique and Pranayama Technique in patients with COPD
- Conditions
- COPD, Shortness of Breath, Quality of Life, Cough
- Trial name
- NCT06463288
- Testing
- Jacobsons Breathing Technique, Pranayama Technique
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
ASTHMA
Breathing Training for Asthma
For the proposed randomized controlled treatment study, the investigators plan to compare the effects of this hypoventilation-based breathing training with a control intervention that will focus on breathing regularity and…
- Trial name
- NCT00975273
- Testing
- Capnometry Assisted Respiration Training, Breathing Awareness
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Southern Methodist University
Childhood Cancer, Cancer Survivors
Diaphragm Structure and Function in Childhood Cancer Survivors
The purpose of this research is to study the feasibility of a specific training program for the breathing muscles (inspiratory muscle training) and the effects on how breathing is regulated during exercise in childhood cancer…
- Trial name
- NCT06205251
- Testing
- POWERbreathe Plus IMT
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Maryland, Baltimore
Chronic Obstructive Pulmonary Disease
Combined Effects of Blow Bottle Device and Postural Drainage in Moderate to Severe Elderly COPD Patients
It will be a randomized clinical trial. Age of selected subjects will be between 40 to 70 years. Data will be collected from Wazirabad institute of cardiology. There will be 2 groups i.e.
- Trial name
- NCT06476769
- Testing
- blow bottle technique, percussion
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Vascular Filling, Newborn
Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life
At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the…
- Conditions
- Vascular Filling, Newborn, Weight Loss, Jaundice
- Trial name
- PERLE (NCT07243054)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pulmonary Disease, Chronic Obstructive, Chronic Bronchitis
Add-on Effects of Tiotropium Over Formoterol in Exercise Tolerance on Chronic Obstructive Pulmonary Disease Patients
The primary objective is to comparatively evaluate the isolated effects of a long-acting beta2-adrenergic (formoterol fumarate 12µg b.i.d.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Chronic Bronchitis, Pulmonary Emphysema
- Trial name
- NCT00680056
- Testing
- Formoterol plus Tiotropium
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Federal University of São Paulo
Acute Dyspnea
PAthwAy of Dyspneic patIent in Emergency in France
This observational retrospective multi-center study focuses on patients treated for acute dyspnea by emergency medical teams. The primary objective is to identify factors associated with the risk of mortality and…
- Trial name
- Fr-PArADIse (NCT06509854)
- Where
- 4 sites in France
- Volunteers
- 89,700 people
- Sponsor
- Pr. Nicolas GIRERD