Clinical trials: Dyssomnia
Sleep Quality, Menopausal Symptoms
Sleep Quality in CHIMES (MF101)
Menopausal women often complain of difficulty sleeping and the transition from pre- to postmenopausal status is associated with an incresase in self-reported sleep disturbance.
- Trial name
- NCT00454441
- Testing
- MF101
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bionovo
Sleep Apnea, Obstructive
New Versus Existing Auto-titrating CPAP Device to Treat Obstructive Sleep Apnea in Adults
Obstructive sleep apnea (OSA) is a condition of disordered breathing characterised by intermittent partial and/or complete upper airway obstruction during sleep.
- Trial name
- APAP (NCT01210261)
- Testing
- Compumedics Somnilink SPAP - Auto-titrating CPAP, Resmed Autoset S8 - Auto-titrating CPAP
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Compumedics Limited
Obstructive Sleep Apnea
AutoSet for Her Quality of Life Clinical Trial
Obstructive sleep apnea (OSA) has detrimental effects on the health and quality of life of suffers. Recent literature has shown that females may be particularly susceptible to adverse the quality of life effects, and that female…
- Trial name
- FEM-PAP (NCT02400073)
- Testing
- AutoSet for Her
- Where
- 3 sites in Germany, Spain
- Volunteers
- 122 people
- Sponsor
- ResMed
Chronic Insomnia
Safety and Efficacy of Ramelteon in Elderly Subjects With Chronic Insomnia.
This purpose of this study is to assess the efficacy and safety of Ramelteon, once daily (QD), in elderly subjects with chronic insomnia.
- Trial name
- NCT00671294
- Where
- 18 sites in United States
- Volunteers
- 100 people
- Sponsor
- Takeda
PostTraumatic Stress Disorder, Sleep Disorder
NightWare Open Enrollment Study
This study will provide measures of safety and efficacy of the NightWare digital therapeutic system (iPhone + Apple watch + proprietary application) for the treatment of nightmare disorder associated with post-traumatic stress…
- Conditions
- PostTraumatic Stress Disorder, Sleep Disorder, Stress Disorder, Sleep Initiation and Maintenance Disorders
- Trial name
- NWOES (NCT03828656)
- Testing
- NightWare Therapeutic System
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- NightWare
Insomnia, Sleep
Vestibular Nerve Stimulation to Improve Sleep
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS) compared to a sham control a as a means of improving sleep as measured by ISI scores and EEG recordings The…
- Conditions
- Insomnia, Sleep, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT04219566
- Testing
- VeNS
- Where
- India
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Excessive Daytime Sleepiness, Narcolepsy
Study to Assess Patient Reported Outcomes With Armodafinil Treatment for Excessive Sleepiness in Adults With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome
The purpose of this study is to assess patient reported outcomes with armodafinil treatment in terms of improvement in sleepiness, satisfaction with treatment, impact on ability to engage in life activities (ie, daily or work and…
- Conditions
- Excessive Daytime Sleepiness, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)
- Trial name
- NCT00228566
- Testing
- Armodafinil
- Where
- 43 sites in United States
- Volunteers
- 247 people
- Sponsor
- Cephalon
Sleep-disordered Breathing, Hypercapnia
Physiological Study to Compare Noninvasive Ventilation (NIV) Masks
Noninvasive ventilation (NIV) is an established therapy that delivers positive pressure to the upper airways to provide respiratory support.
- Trial name
- NCT04926805
- Testing
- CPAP with Mask A, CPAP with Mask B
- Where
- New Zealand
- Volunteers
- 40 people
- Sponsor
- Fisher and Paykel Healthcare
Insomnia
Effect of Activated Charcoal and Time of Dose on the Pharmacokinetics of LY2624803 in Healthy Subject
The purpose of this study is to determine the effect of activated charcoal and dosing time on the absorption of LY2624803 in healthy subjects.
- Trial name
- NCT01236105
- Testing
- LY2624803, Activated Charcoal
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Obstructive Sleep Apnea, Obesity
UBT251 Injection Phase Ⅲ Study (OSA-NPAP)
The objective of this clinical trial is to evaluate the efficacy of investigational drug UBT251 in the treatment of moderate-to-severe obstructive sleep apnea (OSA) with obesity, as well as to assess its safety.
- Trial name
- UNISHAPE-OSA-1 (NCT07767942)
- Testing
- UBT251
- Volunteers
- 150 people
- Sponsor
- The United Bio-Technology (Hengqin) Co., Ltd.
Insomnia Disorder
Phase Ⅰb/Ⅱ Study of HS-10506 in Chinese Participants With Insomnia Disorder
The primary purpose of this phase Ⅰb/Ⅱ study is to investigate the safety, tolerability, pharmacokinetics (the study of the way a drug enters and leaves the blood and tissues over time) after multiple dose administration and the…
- Trial name
- NCT06279286
- Testing
- HS-10506
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive
A Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Participants With Moderate to Severe Obstructive Sleep Apnea, and in Adult and Elderly Participants With Moderate to Severe Chronic Obstructive Pulmonary Disease
The primary purpose of the study is to determine whether lemborexant increases the apnea hypopnea index (AHI) on Day 8 of treatment in adult and elderly participants (adults greater than or equal to [>=] 45 to less than [<] 65…
- Conditions
- Sleep Apnea, Obstructive, Pulmonary Disease, Chronic Obstructive, Respiration Disorders
- Trial name
- NCT04647383
- Testing
- Lemborexant 10 mg
- Where
- 11 sites in United States
- Volunteers
- 63 people
- Sponsor
- Eisai Inc.
Obstructive Sleep Apnea Syndrome
PErsonalized and Adaptive Kinesthetic stImulation Therapy, Based on Cardio-respiratory Holter moNitoring, for Sleep Apnea syndrOmes
This study aims at quantifying the performance of kinesthetic stimulation to reduce the burden of obstructive sleep apneas and hypopneas.
- Trial name
- EKINOx (NCT02789748)
- Testing
- Kinesthetic stimulation
- Where
- 4 sites in France
- Volunteers
- 42 people
- Sponsor
- LivaNova
Insomnia Disorder
Study to Assess the Long Term Safety and Tolerability of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep
Study to assess the long term safety and tolerability of daridorexant in adult and elderly subjects suffering from difficulties to sleep
- Trial name
- NCT03679884
- Testing
- Daridorexant 10 mg, Daridorexant 25 mg, Daridorexant 50 mg
- Where
- 106 sites in United States, Belgium and 12 more
- Volunteers
- 804 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Obstructive Sleep Apnea (OSA), Syndrome, Obstructive Sleep Apnea
Implantable Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea
The objective of this study is to evaluate the safety and preliminary effectiveness of an implantable hypoglossal nerve stimulation system for moderate-to-severe obstructive sleep apnea (OSA).
- Conditions
- Obstructive Sleep Apnea (OSA), Syndrome, Obstructive Sleep Apnea, Respiration Disorders, Sleep Apnea Syndrome, Obstructive
- Trial name
- NCT07711678
- Testing
- Implantable Hypoglossal Nerve Stimulation System
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Beijing Pins Medical Co., Ltd
Skin Condition, Sleep Disturbance
Efficacy Testing of Collagen Drink on Skin Beauty and Sleep Aid
To assess Collagen Drink on skin condition and sleep quality improvement
- Trial name
- NCT05182814
- Testing
- Collagen Juice Drink
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Snoring, Apnea, Obstructive
Dental Appliance to Treat SDB in Children
The clinical hypothesis of this study is that a currently marketed mouthguard may also be able to reduce the symptoms of sleep-disordered breathing in children.
- Conditions
- Snoring, Apnea, Obstructive, Upper Airway Resistance Syndrome, Sleep-Disordered Breathing
- Trial name
- NCT05661747
- Testing
- Vivos Grow/Vivos Way Device
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Vivos BioTechnologies, Inc.
Sleep Apnea (Disorder)
Evaluation of a Disposable Sound Sensor for Recording Respiration During Sleep
Split-night prospective monocentric study to evaluate, in real conditions, the effectiveness of a disposable tracheal sound sensor.
- Trial name
- NCT05272449
- Testing
- Sleep apnea diagnosis
- Volunteers
- 20 people
- Sponsor
- CIDELEC
Sleep Initiation and Maintenance Disorders
The Ability of Songha Night ® to Improve Sleep in Patients With Mild to Moderate Sleep Disturbances
To evaluate the effect of Songha Night ® on insomnia, anxiety and quality of life compared to placebo in patients with mild to moderate insomnia.
- Trial name
- NCT02183714
- Testing
- Songha Night ®
- Volunteers
- 146 people
- Sponsor
- Boehringer Ingelheim
Narcolepsy
Expanded Access to SUVN-G3031 (Samelisant) for the Treatment of Subjects With Narcolepsy
The study is planned to provide expanded access treatment to subjects with narcolepsy who have completed the 2-week treatment phase and follow-up in study CTP2S13031H3 (NCT04072380), and in instances when the investigator as well…
- Trial name
- NCT05530447
- Testing
- Samelisant
- Sponsor
- Suven Life Sciences Limited
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