Clinical trials: Dyssomnia
Insomnia, COPD
A Behavioral Therapy for Insomnia Co-existing With COPD
Difficulty falling asleep, staying asleep or poor quality sleep (insomnia) is common in people with chronic obstructive pulmonary disease.
- Conditions
- Insomnia, COPD, Chronic Obstructive Pulmonary Disease, Fatigue
- Trial name
- NCT01973647
- Testing
- Cognitive Behavioral Therapy for Insomnia, COPD Education, Attention Control
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of Illinois Chicago
Obstructive Sleep Apnea (OSA)
Evaluating the Efficacy of PAP Therapy for Treating OSA in the Home Environment
This study will take between 4-6 months (with first patient first visit to last patient last visit expected to span 3-4 months across all study sites).
- Trial name
- NCT04744038
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- 2 sites in United States, Australia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- ResMed
Obstructive Sleep Apnea
Weight Loss and Obstructive Sleep Apnea
The purpose of this study is to evaluate the effects of moderate energy restriction on the body adiposity, severity of OSA, blood pressure, sympathetic activity, oxidative stress, inflammatory biomarkers, metabolic profile and…
- Trial name
- NCT02206126
- Testing
- Energy Restriction
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Insomnia
Effects of Ramelteon on Driving Ability
The primary purpose of this study is to investigate the effects of bedtime administration of a single dose of ramelteon (8 mg), zopiclone (7.5 mg), and placebo on next-morning on-road driving performance.
- Trial name
- NCT00319215
- Testing
- Ramelteon 8 mg, Zopiclone 7.5 mg
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Utrecht Institute for Pharmaceutical Sciences
Insomnia
Polysomnographic Study Comparing the Use of Dexmedetomidine and Zolpidem to Induce Natural Sleep
The purpose of this study is to determine whether dexmedetomidine can be used to induce normal physiological sleep in humans.
- Trial name
- NCT01485393
- Testing
- Dexmedetomidine, Zolpidem
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Depression, Insomnia
Treatment of Insomnia and Depression in Elders (TIDE)
Insomnia and depression are two of the most prevalent mental health disorders and often co-occur. Health disparities in rural America and among African-Americans are well documented.
- Trial name
- TIDE (NCT01648049)
- Testing
- Integrated Cognitive Behavioral Therapy (CBT), Treatment as usual
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama, Tuscaloosa
Menopause, Insomnia
The Treatment of Insomnia in Symptomatic Peri- and Postmenopausal Women
To examine the change in sleep patterns and mood symptoms in response to eszopiclone (Lunesta) using a double-blind placebo-controlled cross-over study design in perimenopausal and postmenopausal women who experience insomnia…
- Trial name
- NCT00374192
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Insomnia
Effects of Relaxation Training and Stimulus Control in Chronic Insomnia Patients
The study aims to validate the effect of relaxation training and stimulus control on reducing hyperarousal states and improving maladaptive sleep behaviors.
- Trial name
- NCT06658171
- Testing
- Relaxation training and stimulus control, Sleep hygiene education
- Where
- China
- Volunteers
- 88 people
- Sponsor
- Xuanwu Hospital, Beijing
Sleep, Fatigue
Sleep, Mindfulness, and Shift-Level Safety Performance in Perianesthesia Nurses
Perianesthesia (preoperative and postanesthesia care unit, PACU) nurses work rotating, often extended shifts that can disrupt sleep and increase fatigue, both of which are recognized threats to patient safety in high-acuity…
- Conditions
- Sleep, Fatigue, Patient Safety
- Trial name
- NCT07832721
- Testing
- Sleep, Mindfulness, and Shift-Level Safety Observation Toolkit
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Sleep Deprivation, Gut Microbiota
Microbiota Profiles in Newly Married Couples: Potential Effects on Vision, Sleep and Psychometric Parameters
Oral, fecal and conjunctival samples will be collected from participants and will be stored (at - 20 and - 80 ◦C) until further processing.
- Conditions
- Sleep Deprivation, Gut Microbiota, Optometry Examinations, Oral Microbiota
- Trial name
- NCT06638606
- Testing
- Sleep improvement techniques
- Where
- Iran
- Volunteers
- 1,740 people, healthy volunteers welcome
- Sponsor
- Reza Rastmanesh
Sleep Apnea, Obstructive
Upper Airway Toning for Improve the Compliance of CPAP
The obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a breathing disorder which happens at night and consists of the interruption of airflow for more than five seconds.
- Trial name
- NCT01936038
- Testing
- CPAP, Upper Airway Toning for Improve the Compliance of CPAP
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- Fisiolistic
Obstructive Sleep Apnea-hypopnea Syndrome
Effects of Myofunctional Therapy With an Application in Severe Apnea/Hypopnea Sleep Obstructive Syndrome (MTASSAOS)
Background and study aims: Obstructive sleep apnea is a potentially serious sleep disorder. It causes breathing to stop and start repeatedly during sleep.
- Trial name
- MTASSAOS (NCT04438785)
- Testing
- The intervention consists of myofunctional therapy (MT) using the AirwayGym app.
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Quironsalud
Chronic Insomnia, Cancer-related Problem/Condition
The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients
Cancer-related fatigue (CRF) and insomnia are prevalent among cancer patients and have been linked to de-creases in quality of life and poorer overall survivorship.
- Conditions
- Chronic Insomnia, Cancer-related Problem/Condition, Cancer-Related Syndrome
- Trial name
- NCT05226078
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Depression, Bipolar Affective Disorder
The Efficacy of a Transdiagnostic Sleep and Circadian Intervention for Patients With Mental Disorders and Sleep Problems
The aim of this study is to examine the effect of a non-pharmacological transdiagnostic sleep intervention as add on to standard treatment for bipolar disorder, depression and attention deficit disorder.
- Conditions
- Depression, Bipolar Affective Disorder, Attention Deficit Disorder
- Trial name
- NCT05406414
- Testing
- Transdiagnostic sleep and circadian treatment, Active waitlist control group
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- University of Aarhus
Sleep, Wearable Technology
Effects of PeptiSleep on Sleep Quality in Healthy Adults
Examining the effects of PeptiSleep, a plant-based sleep aid, on sleep quality in healthy adults
- Conditions
- Sleep, Wearable Technology, Cortisol, Healthy Participants
- Trial name
- NCT07258433
- Testing
- PeptiSleep, Micro-crystalline cellulose
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
COVID-19 Pandemic, Yoga
Effect of Yoga-based Exercises of Healthcare Workers During COVID-19 Pandemic: Prospective Clinical Trial
To investigate the effect of yoga-based exercises therapy on functional capacity, dyspnea, quality of life, depression, anxiety, and sleep quality in healthcare professionals following COVID-19.
- Conditions
- COVID-19 Pandemic, Yoga, Exercise Therapy, Mind-Body Therapies
- Trial name
- NCT05279443
- Testing
- yoga-based exercises therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Ankara City Hospital Bilkent
Obstructive Sleep Apnea
Mask Study: One-handed vs. Two Handed Technique in Children
During induction of anesthesia in children, the investigators have observed significant variability in mask holding technique at our institution among different anesthesia practitioners.
- Trial name
- NCT03215121
- Testing
- One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Low Anterior Resection Syndrome, Rectal Cancer
The Safety and Efficacy of Transanal Irrigation in Patients With Sleep Disturbance From Low Anterior Resection Syndrome After Rectal Cancer Surgery (TraLARS)
The preservation surgery of the anal sphincter muscle has become the standard procedure in the treatment of rectal cancer and, thanks to advancements in surgical techniques, can now be performed for tumors located closer to the…
- Conditions
- Low Anterior Resection Syndrome, Rectal Cancer, Insomnia, Sleep Disorder
- Trial name
- TraLARS (NCT06222255)
- Testing
- Transanal Irrigation (TAI)
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Sleep Apnea, Obstructive Sleep Apnea
Prevalence, Phenotypes, Predictors and Prognostic Implication of Obstructive Sleep Apnea in Pulmonary Hypertension
The investigators propose a prospective, observational study to determine the impact of OSA and associated physiological parameters on clinical outcomes in patients with pulmonary hypertension.
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Pulmonary Hypertension, Epidemiology
- Trial name
- POSAPH (NCT05595200)
- Testing
- Level III portable sleep study
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Obstructive Sleep Apnea, Obesity
The Relationship Between Obesity-related Molecular Typing and Traditional Chinese Medicine Constitution
Obesity is an epidemic and a growing problem in the world. There are numerous causes of obesity, the most novel and personalized of which is genetic inheritance.
- Trial name
- NCT04326244
- Testing
- blood test, genetic test, Constitution in Chinese Medicine Questionnaire
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Chang Gung Memorial Hospital
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