Clinical trials: Dyssomnia
Obstructive Sleep Apnea
"Six-week Study of the Safety and Efficacy of JZP-110 in the Treatment of Excessive Sleepiness in OSA"
This trial is a 6-week, double-blind, placebo-controlled, randomized-withdrawal, multicenter study of safety and efficacy of JZP-110 in the treatment of excessive sleepiness in adult subjects with OSA.
- Trial name
- OSA (NCT02348619)
- Testing
- JZP-110
- Where
- 30 sites in United States, Finland and 3 more
- Volunteers
- 174 people
- Sponsor
- Jazz Pharmaceuticals
Sleep
The Effects of White Noise for Adult Patients' Sleep Quality in Intensive Care Unit.
Poor sleep quality is one of the most common problems among adult patients in the intensive care unit (ICU). The causes of sleep disturbance are complicated.
- Trial name
- NCT05785130
- Testing
- white noise
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Neurological Diseases or Conditions, Cardiovascular Conditions After Birth
Cereset Research Exploratory Study
The purpose of this study is to evaluate the use of Cereset Research to improve autonomic function in participants with symptoms of stress, anxiety, or insomnia.
- Conditions
- Neurological Diseases or Conditions, Cardiovascular Conditions After Birth, Psychophysiologic Disorders
- Trial name
- NCT03777267
- Testing
- Active CR
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Wake Forest University Health Sciences
Obstructive Sleep Apnea-hypopnea Syndrome
Measuring Various Variables in Obstructive Sleep Apnea
This study included 90 volunteer Obstructive Sleep Apnea Syndrome patients. Only 7 mL blood samples collected from patients. Some biochemicals parameters analyzed in blood serum/plasma.
- Trial name
- OUAS (NCT06284083)
- Testing
- taking a blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Cumhuriyet University
Obstructive Sleep Apnea (OSA)
Development of Advanced Leak Detection Technologies for Positive Airway Pressure Devices Therapies
This study will take between 1-2 months (with first patient first visit to last patient last visit). Each participant will use the supplied PAP device and mask for a period of up to 14 nights.
- Trial name
- NCT04741854
- Testing
- Positive Airway Pressure (PAP) Therapy
- Where
- Australia
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- ResMed
Sleep Apnea, Obstructive
Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.
The solution offered by the Genio System to treat OSA patients with CCC using bilateral HGNS has a favorable risk-benefit ratio, as demonstrated by evidence from 2 studies.
- Trial name
- ACCCESS (NCT05592002)
- Testing
- Genio System
- Where
- 16 sites in United States
- Volunteers
- 124 people
- Sponsor
- Nyxoah S.A.
Sleep Apnea
Effects of Upper Airway Muscle Training on Obstructive Sleep Apnea Severity
The purpose of this study is to evaluate the effect of Asate Silent Sleep Training on obstructive sleep apnea (OSA) severity in patients with mild to moderate OSA.
- Trial name
- NCT04053153
- Testing
- Exercise equipment (a musical instrument that is based on the Medical Didgeridoo)
- Sponsor
- Stanford University
Insomnia, Traumatic Brain Injury
University of Colorado - Restoring Efficient Sleep After TBI
Sleep disturbance is a common condition following traumatic brain injury (TBI) and impairs recovery and quality of life. While efficacious interventions exist many are not accessible to all patients due to a variety of factors…
- Trial name
- CU-REST (NCT05683145)
- Testing
- Computerized Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- VA Eastern Colorado Health Care System
Chronic Pain, Chronic Insomnia
Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain
The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.
- Conditions
- Chronic Pain, Chronic Insomnia, Opioid Use
- Trial name
- NCT06345872
- Testing
- CBT-I, Treatment as usual, Tapered Withdrawal
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obesity, Obstructive Sleep Apnea
Does Treating Obstructive Sleep Apnea in Obese Canadian Youth Improve Blood Sugar Control?
To determine whether, in obese children with moderate-severe Obstructive Sleep Apnea who are prescribed Positive Airway Pressure(PAP) therapy, increased hours of PAP usage per night over a one-year period is associated with a…
- Trial name
- IMPACT Obesity (NCT01116375)
- Where
- 4 sites in Canada
- Volunteers
- 27 people
- Sponsor
- Katz, Sherri Lynne, M.D.
Sleep Initiation and Maintenance Disorders
Efficacy of Head-point Acupuncture on Insomnia
The investigators will conduct a single-center case series study. A total of 40 participants with insomnia will be enrolled. The aim of the study is to assess the therapeutic effect of head-point acupuncture for the treatment of…
- Trial name
- NCT04255901
- Volunteers
- 40 people
- Sponsor
- Chang Gung Memorial Hospital
Pregnancy Related, Depression
Effects of Digitally Delivered and Group-based CBT-I in Pregnant Women With Comorbid Insomnia and Depression
Major depressive disorder (MDD) is a debilitating and recurrent illness associated with a constellation of grave consequences and is among the most common psychiatric disorders during the pregnancy and postpartum periods.
- Conditions
- Pregnancy Related, Depression, Insomnia
- Trial name
- NCT06054256
- Testing
- Group CBT-I, App-based CBT-I, Health related psychoeducation
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- The University of Hong Kong
Insomnia, Schizophrenia
Cognitive Behavioral Therapy for Insomnia (CBT-I) in Schizophrenia(SLEEPINS)
Sleep problems are pervasive in people with schizophrenia. In our study, our goal is to determine whether we can alleviate sleep symptoms and improve quality of life and well-being in patients with major psychiatric disorders…
- Conditions
- Insomnia, Schizophrenia, Schizoaffective Disorder
- Trial name
- SLEEPINS (NCT04144231)
- Testing
- iCBT-I, GCBT-I
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Helsinki University Central Hospital
Gastroesophageal Disease
To Determine if Sleep Deprivation Results in Increased Esophageal Acid Exposure
The purpose of this study is to determine if sleep deprivation results in increased esophageal acid exposure in healthy controls and gastroesophageal reflux disease (GERD) patients.
- Trial name
- IRUSESOM0428 (NCT01093339)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Southern Arizona VA Health Care System
Narcolepsy With Cataplexy
Exploratory Clinical Study to Evaluate Sodium Oxybate (Xyrem) on Potential Endocrine Changes
To monitor for endocrine changes in response to treatment of cataplexy with Xyrem, to focus on the hypothalamic pituitary axis and to confirm the safety of Xyrem on potential endocrine changes.
- Trial name
- NCT00345800
- Testing
- Sodium Oxybate (Xyrem)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- UCB Pharma SA
Obstructive Sleep Apnea
Right Ventricular Function in Patients With Obstructive Sleep Apnea
The purpose of this study is to determine whether patients with obstructive sleep apnea have any changes in right ventricular function evaluated by three dimensional echocardiography.
- Trial name
- NCT01201200
- Where
- Brazil
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Associação Fundo de Incentivo à Pesquisa
Osteo Arthritis Knee, Knee Osteoarthritis
Knee Arthritis Treatment With Autologous Fragmented Adipose Tissue and PRP - Comparison of Two Treatment Methods
This is a prospective, randomized, controlled study. The purpose of this study is to assess functional and clinical changes among patients with symptomatic knee OA treated with intra-articular injections of autologous adipose…
- Conditions
- Osteo Arthritis Knee, Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT04321629
- Testing
- autologous adipose tissue transfer, PRP injections
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Rehasport Clinic
Obstructive Sleep Apnea
Lifestyle Intervention for OSA in Adults
Obstructive sleep apnoea (OSA) is characterized by the presence in the polysomnogram test of more than five apnoea-hypopnoea episodes per hour of sleep (apnoea-hypopnoea index, AHI > 5), each episode lasting more than 10 seconds…
- Trial name
- NCT03851653
- Testing
- Lifestyle Intervention
- Where
- Spain
- Volunteers
- 89 people
- Sponsor
- Universidad de Granada
Sleep Apnea, Obstructive, Brain Ischemia
The Effect of Positional Device on the Obstructive Sleep Apnea in Patients With Ischemic Stroke
Supine positioning was reported to increase upper airway collapsibility, apnea frequency and duration. Positional therapy, designed to minimize supine sleep, was reported to be beneficial in the general sleep apnea population.
- Trial name
- NCT01699139
- Testing
- positional device, lumbar corset
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- Chang Gung Memorial Hospital
Recurrent Tonsillitis, Peritonsillar Abscess
Auricular Acupuncture for The Treatment of Post-Tonsillectomy Pain
The goal of this study is to assess the role of battlefield acupuncture in the reduction of pain scores status post adult tonsillectomy.
- Conditions
- Recurrent Tonsillitis, Peritonsillar Abscess, Obstructive Sleep Apnea
- Trial name
- NCT01790477
- Testing
- Auricular Acupuncture
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
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