Clinical trials: ECG
Cutaneous T-Cell Lymphoma/Mycosis Fungoides
PK and ECG Determinations Following 8 Weeks of HyBryte Treatment for Cutaneous T-Cell Lymphoma
To assess the blood levels of hypericin and any electrocardiogram (ECG) changes during 8 weeks of HyBryte (topical hypericin ointment) photodynamic therapy.
- Trial name
- NCT05380635
- Testing
- Hypericin
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Soligenix
Heart Failure
ECG Belt for CRT Response
The purpose of this clinical study is to compare ECG Belt Research System managed cardiac resynchronization therapy (CRT) patients and a control CRT group with respect to left ventricular (LV) remodeling.
- Trial name
- NCT03504020
- Testing
- ECG Belt Research System
- Where
- 43 sites in United States, Belgium and 5 more
- Volunteers
- 498 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Epilepsy
Study to Evaluate a New Device Designed to Collect Heart Activity and Body Movement Data
This study is designed to collect data to support development of a novel product designed to sense changes in heart rate or movement during periods of sleep in people with epilepsy.
- Trial name
- NCT01626599
- Testing
- ProGuardian
- Where
- 6 sites in United States
- Volunteers
- 147 people
- Sponsor
- Cyberonics, Inc.
Healthy Volunteers
Multiple-Dose Study of Effect of Bardoxolone Methyl on QT/QTC Interval Volunteers
This is a single-center, multiple-dose, randomized, double-blind, double-dummy, placebo-controlled, active-comparator, parallel study in healthy volunteers.
- Trial name
- NCT01689116
- Testing
- Bardoxolone Methyl 20mg, Bardoxolone Methyl 80mg, Moxifloxacin 400mg
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Biogen
Anemia
A Study of the Electrocardiogram Effects and Pharmacokinetics of Ferumoxytol in Healthy Men and Women
This study will define the effects of ferumoxytol on electrocardiogram (ECG) data as well as evaluate pharmacokinetics
- Trial name
- NCT00360425
- Testing
- ferumoxytol, moxifloxacin
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- AMAG Pharmaceuticals, Inc.
Atrial Fibrillation (AF), Paroxysmal Atrial Fibrillation (PAF)
Multi-Centre Based Study Recognition of Atrial Fibrillation With the Corsano CardioWatch 287-2 System
This concerns a multi-center, single-arm, diagnostic accuracy study. In this study, a wristband that monitors heart rythm is assessed in clinical and free living conditions.
- Trial name
- COR-AF (NCT06955273)
- Testing
- Corsano CardioWatch 287-2
- Where
- Netherlands
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Corsano Health B.V.
Carcinoma, Renal Cell
VEG111485: A QTc Study of Pazopanib
This is a Phase I, randomized, double-blind, placebo-controlled, study to estimate the effects of daily oral dosing of 800 mg pazopanib on electrocardiographic parameters (QTc interval duration) as compared with placebo in…
- Trial name
- NCT00861029
- Testing
- Pazopanib, Moxifloxacin
- Where
- 8 sites in United States
- Volunteers
- 2 people
- Sponsor
- GlaxoSmithKline
Systemic Lupus Erythematosus, Healthy Participants
An Investigational Study of Experimental Medication BMS-986165 in Healthy Participants to Study Electrocardiogram Effects
This is a study to investigate the experimental medication BMS-986165 in healthy participants in order to study the effects it has on electrocardiogram results.
- Trial name
- NCT03541564
- Testing
- BMS-986165, Moxifloxacin
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Healthy
Assess the Effect of Cangrelor at the Therapeutic Dose and a Supratherapeutic Dose Level on the QT/QTc Interval in Healthy Volunteers
To assess the safety of cangrelor on cardiac repolarization as measured by electrocardiogram (ECG) at therapeutic and supratherapeutic doses.
- Trial name
- NCT00699504
- Testing
- cangrelor, moxifloxacin
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- The Medicines Company
No Specific Conditions Under Study. Primary Focus: Adult Subjects Who Require PICC Placement
Assessment of the Precision of the Sherlock 3CG Tip Positioning System
Phase I determine the location of the peripherally inserted central catheter (PICC) tip upon observation of maximum p-wave amplitude Phase II determine the precision of PICC placement in the Sherlock 3CG group versus the standard…
- Trial name
- STAT-PICC (NCT01275430)
- Testing
- Sherlock 3CG, Blind Placement
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- C. R. Bard
Healthy Volunteers
Cardiac Safety Evaluation of P03277
The study is a Phase I, Single center, Randomized, Cross-over Double-blind Placebo-controlled and Open-label Positive-controlled (moxifloxacin) in healthy volunteers.
- Trial name
- NCT03657264
- Testing
- P03277 0.1 mmol/kg, Moxifloxacin 400mg, NaCl 0.9%
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Guerbet
Ventricular Ejection Fraction, LVF
AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor
This prospective, multicenter, cluster-randomized controlled study aims to evaluate the accuracy of an investigational artificial intelligence (AI) Software as a Medical Device (SaMD) designed to compute ejection fraction (EF)…
- Conditions
- Ventricular Ejection Fraction, LVF, LV Dysfunction, Atrial Enlargement
- Trial name
- EFACT (NCT06699056)
- Testing
- 15-minutes of sitting during COR ECG Acquistion
- Where
- 8 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Peerbridge Health, Inc
Heart Diseases, Cardiac Surgery
Evaluation of an AI-Based Lightweight ECG Telemetry Monitoring System
This study aims to evaluate the clinical applicability of the AI-based lightweight ECG monitoring system (MEMO Patch Plus) as a telemetry ECG monitoring system in patients undergoing cardiac surgery.
- Conditions
- Heart Diseases, Cardiac Surgery, Cardiac Arrhythmias
- Trial name
- NCT07725445
- Testing
- MEMO Patch
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- HUINNO Co., Ltd
Patients Requiring Peripherally Inserted Central Venous Catheters
Application of Intracavity Electrocardiogram Positioning Technique in PICC
This study was a prospective, multicenter, randomized controlled study. The study aimed to exploring the influence of PICC intra catheter guide wire or PICC conductive tip as intra luminal electrode on the positioning accuracy of…
- Trial name
- NCT05555160
- Testing
- PICC
- Volunteers
- 3,051 people
- Sponsor
- Shandong Branden Med.Device Co.,Ltd
Emotion, Expressed
Study of Evoked Emotional Responses
Mental health and emotional awareness are a crucial need of the time. Changing lifestyles, stress, and anxiety are seen more commonly and affect many adults in the United States and other countries.
- Trial name
- NCT04044261
- Testing
- Emotion induction using video
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Monsoon Design Studio LLC
Healthy
The Effect of Hydrocodone Bitartrate (HYD) Extended-Release Tablets on QT /QTc Intervals in Healthy Adult Subjects
Evaluate the effect of multiple doses (once daily for 3 days each of HYD 80, 120, and 160 mg tablets) on the QT/QTc interval.
- Trial name
- NCT02243241
- Testing
- HYD, Moxifloxacin
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Purdue Pharma LP
Atrial Arrhythmia, QT Interval, Variation in
QT Changes as Detected From LINQ ECG During Antiarrhythmic Loading (LINQ QT)
The LINQ QT Study is a prospective, non-randomized, multi-center, observational, post-market clinical study investigating QT interval changes due to antiarrhythmic drug loading.
- Conditions
- Atrial Arrhythmia, QT Interval, Variation in, Arrhythmias, Cardiac
- Trial name
- LINQ QT (NCT05488470)
- Testing
- LINQ/LINQ II
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Healthy
Study to Assess the Effect of Macitentan on the Electrocardiogram (ECG) in Healthy Male and Female Subjects
The study is intended to demonstrate that macitentan does not have an effect on cardiac repolarization exceeding the threshold of regulatory concern after repeated administration of daily oral doses of 10 and 30 mg to healthy…
- Trial name
- NCT02050802
- Testing
- Moxifloxacin 400 mg, Macitentan 10 mg, Macitentan 30 mg
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Actelion
Arrhythmias, Cardiac
12 Lead ECG Database
The purpose of this investigation is to collect a database of simultaneous electrocardiogram (ECG) recordings from the SANSA device and a reference 12-lead ECG recording device.
- Trial name
- NCT06513637
- Testing
- 12-Lead ECG and home sleep study (HST) diagnostics
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Huxley Medical, Inc.
Acne Vulgaris
A Thorough ECG Study in Subjects With Acne Vulgaris Treated With SB204
A Double-Blind, Double-Dummy, Randomized, 4-Period Crossover Study to Define the ECG Effects of SB204 Using a Clinical and Supratherapeutic Dose Compared with Placebo and Moxifloxacin (a Positive Control) in Subjects with Acne…
- Trial name
- NCT02581072
- Testing
- SB204 4%, SB204 8% or 12%, Vehicle
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Novan, Inc.