Clinical trials: ED
Cancer Patients, Emergencies
Epidemiological Characteristics and Prognosis Factors of Cancer Patients Admitted at French Emergency Departments
Patients with cancer or hematological malignancy are susceptible to present acute complications linked to their disease or to their specific treatments (dyspnea, sepsis, coma, hemorrhagic syndrome).
- Trial name
- EPICANCER (NCT03393260)
- Where
- France
- Volunteers
- 1,380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetic Ketoacidosis
Intravenous Fluids in Adults With Diabetic Ketoacidosis in the Emergency Department
Diabetes mellitus is a common chronic disease. It is estimated that up to 40% of adults may develop diabetes in their lifetime. Patients with poorly controlled blood sugars often visit the emergency department for treatment of…
- Trial name
- BRISK-ED (NCT04926740)
- Testing
- Ringer's lactate
- Where
- Canada
- Volunteers
- 74 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Erectile Dysfunction, Peripheral Arterial Disease
Predicting Peripheral Arterial Disease in Men With Erectile Dysfunction
Erectile dysfunction is a common complaint and is found frequently in men with hyperlipidemia, hypertension, diabetes and those who smoke. ED may also be an early warning of peripheral arterial disease.
- Trial name
- PREPARED (NCT00743613)
- Testing
- Sexual Health Inventory for Men (SHIM), Ankle-Brachial Index (ABI)
- Where
- 5 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Bruton Avenue Family Practice
Obesity, Overweight
A Cafeteria Based Study of Weight Gain Prevention
The dramatic rise in overweight and obesity during the past several decades can be explained by environmental changes that foster increased energy intake and decreased energy expenditure.
- Trial name
- Cafeteria (NCT00573482)
- Testing
- REDE, control
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
PAD
Endovascular Denervation Improves Limb Ischemia in Patients With Peripheral Artery Disease
Sympathetic overactivity partly promotes the development of peripheral artery disease which mainly leads to ischemia of the lower limbs.
- Trial name
- NCT04060797
- Testing
- endovascular denervation, PTA
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Zhongda Hospital
Gout
Gout in the ED and Improving Research Participation
The prevalence of gout has been steadily increasing over several decades and is correlated with the rising burden of obesity, chronic cardiac and renal disease; all conditions overrepresented in the Southeastern U.S.
- Trial name
- NCT04075903
- Testing
- Storytelling
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Alabama at Birmingham
Acute Coronary Syndrome
Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myocardial Infarction
1. In chest pain patients with suspected acute coronary syndrome, a 2-hr delta Troponin-I as measured by the i-STAT immunoassay reliably identifies and excludes an acute myocardial infarction. 2.
- Trial name
- NCT02002546
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Chattanooga-Hamilton County Hospital Authority
Extensive Stage Lung Small Cell Carcinoma, Recurrent Lung Small Cell Carcinoma
Cisplatin/Carboplatin and Etoposide With or Without Nivolumab in Treating Patients With Extensive Stage Small Cell Lung Cancer
This randomized phase II clinical trial studies whether the addition of nivolumab to cisplatin (or carboplatin) and etoposide will improve outcomes when treating patients with extensive stage small cell lung cancer.
- Trial name
- NCT03382561
- Testing
- Carboplatin, Cisplatin, Etoposide
- Where
- 779 sites in United States
- Volunteers
- 160 people
- Sponsor
- National Cancer Institute (NCI)
Renal Colic
Comparative Efficacy of IV Dexamethasone vs. Nebulized Terbutaline for Renal Colic Pain in the ED
Adult patients (18-55 years of age) with clinical diagnosis of acute renal colic (sudden sharp colic flank pain with or without radiation to genitalia or groin and with or without urinary symptoms) who had pain score of 5 or more…
- Trial name
- NCT06980727
- Testing
- Terbutaline 2.5 mg, Dexamethasone
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Vertigo, Unsteadiness
Accuracy of a Diagnostic Algorithm for the Differential Diagnosis of Vertigo in the ED: the STANDING.
This study evaluate the diagnostic accuracy of a simplified clinical algorithm (STANDING) for the differential diagnosis of acute vertigo in the emergency department.
- Trial name
- STANDING (NCT02782962)
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Mechanical Ventilation, Respiratory Failure
The Emergency Department Sedation Pilot Trial
The ED-SED Pilot is a multicenter, prospective, before-and-after study conducted on 344 mechanically ventilated emergency department patients at three academic medical centers: Washington University in St.
- Trial name
- ED SED Pilot (NCT04410783)
- Testing
- Education, Standard post intubation sedation practices
- Where
- 3 sites in United States
- Volunteers
- 1,771 people
- Sponsor
- Washington University School of Medicine
Mental Disorder
Engaging Patients With Mental Disorders From the ED in Outpatient Care
This study will compare the effectiveness of professional and peer care managers in improving linkage to and engagement in outpatient care after an emergency department (ED) discharge, as well as the mechanisms by which…
- Trial name
- EPIC (NCT02989805)
- Testing
- Care Management
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- Emory University
Pain
Intravenous Lidocaine and Ketorolac for Pain Management
The literature regarding analgesic modalities, their combinations and routes of administrations for patients with pain related to renal colic is expanding.
- Trial name
- NCT02902770
- Testing
- Lidocaine, Ketorolac Tromethamine, Normal Saline Drip
- Volunteers
- 150 people
- Sponsor
- Antonios Likourezos
Sepsis, Septic Shock
Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients.
Infections in critically ill patients are a major healthcare problem and an important source of morbidity and mortality. Since critically ill patients often have altered pharmacokinetics (PK) compared to non-critically ill…
- Conditions
- Sepsis, Septic Shock, Infection, Bacterial, Critically Ill
- Trial name
- PHARAOH (NCT04470973)
- Testing
- Cefuroxime, Amikacin
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Migraine, Tension-type Headache
Comparing Naproxen to Sumatriptan for Emergency Headache Patients
2/3 of patients discharged from an emergency department after treatment for an acute headache will still be bothered by headache within 24 hours of emergency department (ED) treatment.
- Conditions
- Migraine, Tension-type Headache, Primary Headache Disorder
- Trial name
- HEDNet2 (NCT00449787)
- Testing
- Sumatriptan 100 mg, Naproxen
- Where
- 2 sites in United States
- Volunteers
- 401 people
- Sponsor
- Montefiore Medical Center
Pain, Acute
Analgesic Efficacy of Orally Administered VTS-K for Pain Management
A combination of ketamine and aspirin for the treatment of acute MSK pain in the ED would confer multimodal analgesia, with the contributions of aspirin and ketamine to an opioid sparing effect.
- Trial name
- NCT04702555
- Testing
- VTS-K
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Antonios Likourezos
Pneumonia
Pilot Deployment of ePNa Into Epic EHR
Intermountain Health has developed a electronic decision support tool to help doctors provide the best care for pneumonia. The purpose of this study is to enhance the existing tool (called ePneumonia (electronic Pneumonia) or…
- Trial name
- ePNa-Epic (NCT06008314)
- Testing
- ePNa
- Volunteers
- 6,917 people, healthy volunteers welcome
- Sponsor
- Nathan Dean
Kidney Injury
I USE LR in the ED
To study the difference in mortality and major adverse kidney events during and after treatment in the emergency department with intravenous fluids per standard of care at 30 days before and after the system-wide implementation.
- Trial name
- NCT03807648
- Testing
- Data Inclusion
- Where
- United States
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Homosexuality, Gender Identity
Patient Centered Methods to Collect Sexual Orientation and Gender Identity Status in the ED
This trial is the final phase of a three phase PCORI-funded study to develop and test patient-centered approaches to collect sexual orientation and gender identity (SO/GI) information in the ED.
- Trial name
- EQUALITY (NCT02701049)
- Testing
- Methods to collect SO/GI information in the ED
- Volunteers
- 749 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Migraine
Migraine Treatment in ED
Randomized pilot feasibility study evaluating the impact of introducing behavioral treatment for migraine in the Emergency Department (ED) and prescribing migraine preventive medications in the ED.
- Trial name
- NCT02643719
- Testing
- Relaxation Therapy, Topiramate, Standard of Care
- Sponsor
- NYU Langone Health