Clinical trials: ED
Myofascial Pain, Chronic Pain
FDM for Subacute and Chronic Extremity Pain in the ED
STUDY PURPOSE: To identify whether a low-cost, minimally invasive, one-time manual medicine intervention (fascial distortion model, FDM) is effective for the management of subacute and chronic extremity pain in the emergency…
- Conditions
- Myofascial Pain, Chronic Pain, Extremities Disorders, Osteopathic Manipulation
- Trial name
- NCT04555239
- Testing
- Fascial Distortion Model (FDM), Standard Care
- Where
- 4 sites in United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Influenza-Like Illness, Influenza
Impact of Rapid Flu Testing in BMC ED
The purpose of the study is to compare Emergency Department patients who undergo influenza testing using an FDA-approved point-of-care device (Cobas Liat Influenza A/B assay) located in the ED, to patients whose samples are sent…
- Trial name
- FluProcess (NCT02979730)
- Testing
- Core Lab Test, ED Point of Care Test
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Boston Medical Center
Emergency Medicine, Well-Being, Psychological
ED Adaptive Staffing Study
Emergency Departments (EDs) across Ontario are being inundated with unprecedented high patient volumes and a staffing shortage that directly impacts patient care and flow.
- Trial name
- FAST-ED (NCT05937763)
- Testing
- Staffing model
- Where
- Canada
- Volunteers
- 5,917 people
- Sponsor
- Oak Valley Health
Sepsis, Septic Shock
Multicenter Symphony™ IL-6 Monitoring Sepsis ED Pilot Study
The primary objective of this study is to establish an IL-6 concentration cutoff that predicts sepsis or septic shock (according to the Third International Consensus Definitions (Sepsis-3 criteria)) in patients who are admitted…
- Trial name
- SYMON III (NCT07425587)
- Where
- 5 sites in United States
- Volunteers
- 450 people
- Sponsor
- Bluejay Diagnostics, Inc.
Influenza
ED Influenza Therapeutic Pilot Study: Oseltamivir vs. Peramivir
This pilot study is designed to demonstrate the feasibility of utilizing Emergency Departments (EDs) as a primary site for subject enrollment in clinical trials evaluating influenza therapeutics, and to provide pilot data for…
- Trial name
- NCT02609399
- Testing
- Oseltamivir, Peramivir
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Johns Hopkins University
Emergency Medicine
Propensity to Hospitalize Patients From the ED in European Centers.
The peer-to-peer comparison means center-to-center comparison, which requires adjusting for possible differences among centers to be fair and convincing.
- Trial name
- eCREAM-UC1 (NCT06354764)
- Testing
- no intervention
- Where
- 2 sites in Italy
- Volunteers
- 162,000 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Kidney Failure, Chronic, Arrhythmias, Cardiac
HOLT-ED: Holter-monitoring in End-stage Renal Disease
The main objective of this prospective cohort study is to assess arrhythmia burden and glycemic variability in a multicenter cohort of patients with end-stage renal disease using a sufficient observation period in order to…
- Conditions
- Kidney Failure, Chronic, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- NCT04876963
- Testing
- Holter-monitor
- Where
- 3 sites in Denmark
- Volunteers
- 268 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
BPH, Erectile Dysfunction
Uroxatral in Men With Benign Prostate Hypertrophy (BPH) and Erectile Dysfunction (ED)
Uroxatral (alfuzosin) may not only help BPH symptoms but may also improve sexual function in males with BPH and ED.
- Trial name
- NCT00256399
- Testing
- Alfuzosin 10 mg
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Frailty, Frailty Syndrome
Loss of Independence - a Rapid Alternative to Frailty Screening in a Swedish ED Setting
This prospective observational study will investigate the correlation of a surrogate marker of frailty in relation to serious outcomes.
- Conditions
- Frailty, Frailty Syndrome, Emergency Department, Geriatric Assessment
- Trial name
- NCT04888884
- Where
- 3 sites in Sweden
- Volunteers
- 1,800 people
- Sponsor
- University Hospital, Linkoeping
Alcohol Drinking
Emergency Department (ED) Adolescent Alcohol Prevention Intervention
The aim of the present study is to prevent or delay the initiation of alcohol use among young adolescents being seen in a pediatric emergency department, by enhancing parental monitoring and improving parent/adolescent…
- Trial name
- NCT01105416
- Testing
- Brief Prevention Intervention (BPI), ESC
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Rhode Island Hospital
Diabetes Mellitus, Erectile Dysfunction
Is There a Benefit From Addition of Exercise in Diabetic Patients With ED Who Complain Low Vitamin D?
males with diabetes complain impotence in the presence of low vitamin D deficiency. pharacmological treatment of low vitamin D levels is necessary but changing lifestyle by performing exercise is also important
- Conditions
- Diabetes Mellitus, Erectile Dysfunction, Vitamin D Deficiency
- Trial name
- NCT07366970
- Testing
- exercise and vitamin D intake, vitamin D intake
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Extensive-stage Small Cell Lung Cancer
A Study of Niraparib as Maintenance Therapy Following First-Line Platinum-Based Chemotherapy in Patients With Extensive Stage Small Cell Lung Cancer
Niraparib is a PARP inhibitor. The study is a 2:1 randomized, double-blind, placebo-controlled, multi-center,phase 3 study of ZL-2306 (niraparib) as maintenance therapy following first-line platinum-based chemotherapy in patients…
- Trial name
- NCT03516084
- Testing
- ZL-2306(nirapairb)
- Where
- 33 sites in China
- Volunteers
- 185 people
- Sponsor
- Zai Lab (Shanghai) Co., Ltd.
Simulation, Dizziness
Virtual Patient Education From Real Cases
Misdiagnosis of neurological conditions is common in healthcare settings, sometimes with devastating consequences. Most diagnostic errors result from failures in bedside diagnostic reasoning.
- Conditions
- Simulation, Dizziness, Vertigo, Stroke
- Trial name
- ViPER (NCT04553640)
- Testing
- Group A/Intervention Curriculum, Group B/Control Curriculum
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Erectile Dysfunction
Safety and Efficacy of the VERTICA® RF Device for the Treatment of ED
Adult subjects with mild to moderate and moderate ED who meet the study eligibility criteria will be enrolled in the study. The enrolled subjects will be randomized by a 1:1 ratio to receive the Active or Sham VERTICA® treatment.
- Trial name
- NCT06167733
- Testing
- VERTICA Active device
- Where
- 6 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- OHH-MED Medical Ltd
Erectile Dysfunction, Urinary Incontinence
Male Pelvic Floor Muscle Rehabilitation Exercises
Phase I G128 Study Objective The ischiocavernosus (IC) and bulbospongiosus (BS) muscles are vital components of the superficial perineal layer, serving as the foundation for male sexual health and performance.
- Conditions
- Erectile Dysfunction, Urinary Incontinence, Premature Ejaculation
- Trial name
- NCT07451808
- Testing
- Male Pelvic Floor Rehabilitation #1
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dream Video LLC
Penicillin Allergy, Pediatric Emergency Medicine
Oral Challenge in the Pediatric ED
Our primary objective was to demonstrate the feasibility of utilizing a novel penicillin allergy questionnaire in the PED to identify a low-risk group of patients who will complete an oral challenge in the PED to test for an…
- Trial name
- OPEN (NCT03404804)
- Testing
- Amoxicillin
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Medical College of Wisconsin
Rhinitis, Allergic, Seasonal, Asthma
Randomized, Placebo Controlled, Crossover Study in an Environmental Challenge Chamber to Assess Safety & Efficacy of Three Oral Doses of BI 671800 Versus Fluticasone Propionate and Montelukast in Sensitive Seasonal Allergic Rhinitis Patients Out of Season
The objective of the current study is to investigate the efficacy, safety and tolerability of BI 671800 ED using three dose levels of BI 671800 ED (50 mg, 200 mg and 400 mg), administered twice daily compared to FP (fluticasone…
- Trial name
- NCT01007721
- Testing
- BI 67100 ED 25 mg, BI 671800 ED 100 mg
- Where
- Germany
- Volunteers
- 146 people
- Sponsor
- Boehringer Ingelheim
Acute Myocardial Ischemia
Non Invasive dP/dt to Detect an Acute Ischemic Myocardial Dysfunction in Emergency Department
Most patients presenting to the emergency department with chest discomfort have a nonischemic ECG and biomarkers of myocardial necrosis within normal limits.
- Trial name
- dP/dtAMDED (NCT02138604)
- Where
- Tunisia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Hyperkalemia
A Study to Detect Hyperkalemia Using Smartphone-enabled Electrocardiogram (EKG)
The purpose of this study is to validate the real-world performance of a previously developed Artificial Intelligence - Electrocardiogram (AI-ECG) algorithm for identification of hyperkalemia with a six-lead mobile-enhanced…
- Trial name
- REACT (NCT05441852)
- Where
- United States
- Volunteers
- 1,151 people
- Sponsor
- Mayo Clinic
Aortic Dissection
The DAShED (Diagnosis of Aortic Syndrome in the ED) Study
Acute aortic syndrome (AAS) is a life-threatening emergency condition affecting the upper aorta affecting ~4000 people in the (United Kingdom; UK) a year with an ED misdiagnosis rate as high as 38%.
- Trial name
- DAShED (NCT05582967)
- Testing
- Completion of focused Electronic Case Report Form
- Where
- 25 sites in United Kingdom
- Volunteers
- 5,548 people
- Sponsor
- NHS Lothian