Clinical trials: ED
Alcohol Misuse
Advancing Scalable Alcohol Brief Interventions in the ED: A Trial of Conversational AI With Digital Reinforcements
The goal of this clinical trial is to learn if a novel digital strategy combining a generative AI counseling agent (MICA) and weekly SMS boosters works to reduce risky drinking among Emergency Department patients.
- Trial name
- MICA-ED (NCT07661563)
- Testing
- MICA, TRAC
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Stanford University
Altered Mental Status
Intranasal Dexmedetomidine vs. Standard of Care for Emergency Department (ED) Procedural Sedation in the Older Adult
The purpose of the study is to determine if intranasal dexmedetomidine could be an alternative to the current standard of care (injectable benzodiazepines or antipsychotics) for sedation prior to computerized tomography (CT) or…
- Trial name
- NCT06370442
- Testing
- Dexmedetomidine, Lorazepam, Haloperidol
- Volunteers
- 60 people
- Sponsor
- State University of New York - Upstate Medical University
Tobacco Use
Strategies to Help Adult ED Patients Quit Smoking
The purpose of this study is to determine whether a brief, focused intervention in the hospital emergency department is effective in helping adults quit smoking.
- Trial name
- NCT00297466
- Testing
- transdermal nicotine patches, Motivational interview
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Asthma
Use of Text Messages to Improve Care For Children Following an ED Visit for Asthma
BACKGROUND Asthma is a prevalent and troublesome pediatric condition. In 2013, Emergency Department (ED) providers treated over 3,500 cases of asthma-related complaints at Children's Hospitals and Clinics of Minnesota.
- Trial name
- NCT02436070
- Testing
- Targeted text messages, General text messages
- Where
- 2 sites in United States
- Volunteers
- 195 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Substance Use (Drugs, Alcohol)
Emergency Department-Substance Use Screening, Motivational Interviewing and Active Referral Targeting Substance Use Disorder and Overdose Prevention
The purpose of this research study is to learn if an emergency department screening and telehealth intervention reduces substance use among individuals receiving emergency department treatment at The Ohio State University Wexner…
- Trial name
- ED-SMART (NCT07527871)
- Testing
- ED-SMART intervention, Substance use information
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- Purdue University
Endotracheal Tube Wrongly Placed During Anesthetic Procedure
Ultrasonography in Confirming Proper Position of Endotracheal Tube
The purpose of this study is to assess the applicability of using ultrasonography in confirmation of the position of the endotracheal tube (ETT) after intubated to patients.
- Trial name
- NCT01373437
- Testing
- Ultrasonography (Sonosite )
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Erectile Dysfunction
LI-ESWT Versus Sham Therapy in Men With ED
Hong Kong has an aging population. By the year of 2036, more than 30% of our population will be older than 65 years old1. Aging in male has been shown to correlate with the risk of erectile dysfunction(ED).
- Trial name
- NCT04721834
- Testing
- Low-intensity Extracorporeal Shockwave Therapy
- Volunteers
- 84 people
- Sponsor
- Hospital Authority, Hong Kong
Opioid Use Disorder
ED Observation for Opioid Use Disorder
This is a multicenter, randomized clinical comparative effectiveness trial (RCT) in which patients with untreated OUD presenting to a Northwell Health Emergency Department (ED), NYULH-Brooklyn, NYULH-Tisch, and Bellevue Hospital…
- Trial name
- NCT05064826
- Testing
- Extended Visit with Observation, Standard ED Visit
- Where
- 6 sites in United States
- Volunteers
- 170 people
- Sponsor
- NYU Langone Health
Lacerations, Abscess
Effectiveness of Nitrous Oxide in the ED
This will be a randomized control trial. All patients for whom an emergency provider determines that abscess drainage or laceration repair are necessary will be considered for enrollment.
- Trial name
- NCT02703233
- Testing
- Nitrous Oxide, Oxygen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Impotence
A Study Of The Safety and Efficacy Of Viagra In Men With Erectile Dysfunction Who Do Not Self Identify.
To compare the efficacy and safety of Viagra (sildenafil citrate) vs. placebo for the treatment of men with ED and at least 1 prespecified risk factor who do not self identify as having ED.
- Trial name
- NCT00343200
- Testing
- Viagra (sildenafil citrate)
- Where
- 48 sites in United States
- Volunteers
- 371 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Acute Coronary Syndrome, Pulmonary Embolism
Assessment of Acute Disease to Reduce Imaging Costs
Overtesting for Acute Coronary Syndrome(ACS) and Pulmonary Embolism (PE) in low risk Emergency Department(ED) patients can increase exposure of nondiseased patients to radiation, intravenous contrast and anticoagulation.
- Trial name
- QUAADRICs (NCT01059500)
- Testing
- Webtool
- Where
- 4 sites in United States
- Volunteers
- 550 people
- Sponsor
- Wake Forest University Health Sciences
Patient Satisfaction, Patient Preference
Patient Perspective Midline Catheter in the Emergency Department
This study examines the patient satisfaction and perspective on the use of ultrasound guided midline intravenous catheters compared to standard ultrasound guided peripheral catheters.
- Trial name
- NCT05607238
- Testing
- Ultrasound Guided Vascular Access - Midline catheter, Ultrasound Guided Vascular Access - peripheral IV
- Sponsor
- Wake Forest University Health Sciences
Erectile Dysfunction
A New Sildenafil Oral Film in Patients With Erectile Dysfunction
This is a Phase III, prospective, interventional, multi-center, randomized, double-blind, flexible-dose, placebo-controlled, parallel group clinical study required by FDA to demonstrate the efficacy and safety of Sildenafil oral…
- Trial name
- NCT05490680
- Testing
- Sildenafil Oral Film 25 mg, 50 mg, 75 mg or 100 mg
- Where
- 18 sites in United States
- Volunteers
- 488 people
- Sponsor
- IBSA Institut Biochimique SA
Erectile Dysfunction Due to Venous Disorder, Erectile Dysfunction (ED)
Embolosclerotherapy Versus Deep Dorsal Vein Revascularization in Venogenic Erectile Dysfunction
Venous leakage is one of the causes of erectile dysfunction and can be managed using different treatment modalities, including surgical ligation and percutaneous embolization.
- Trial name
- venogenic ED (NCT07604194)
- Testing
- Endovascular embolosclerotherapy, Revacularization of deep dorsal vein
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University Hospital
Extensive Disease, First-Line
Topotecan and Cisplatin Versus Etoposide and Carboplatin in 1st Line Treatment of Patients With Small Cell Lung Cancer and Extensive Disease (SCLC-ED)
Randomised trial comparing standard chemotherapy with carboplatin and etoposide with a combination of topotecan and cisplatin in patients with inoperable lung cancer of small cell type.
- Conditions
- Extensive Disease, First-Line, Small Cell Lung Cancer
- Trial name
- NCT00812266
- Testing
- topotecan + cisplatin, Etoposide + carboplatin
- Where
- Denmark
- Volunteers
- 281 people
- Sponsor
- Danish Oncological Lung Cancer Group
Erectile Dysfunction
Adipose-derived SVF for Treatment of Erectile Dysfunction (ED)
This study will examine the safety and feasibility of a single injection of autologous adipose-derived stromal vascular fraction to treat erectile dysfunction.
- Trial name
- NCT03886402
- Testing
- GID SVF-2
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- GID BIO, Inc.
Medication Adherence
Text-message Support to Improve Oral Antibiotic Adherence After ED Discharge
The investigators are testing the hypothesis that patients who are exposed to daily text-message (TM) assessments with feedback will have better adherence to prescription than those patients not exposed to TM-based queries with…
- Trial name
- ImpACT (NCT01388465)
- Testing
- Mobile phone text messaging
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pittsburgh
Acute Coronary Syndrome, High-Risk Chest Pain
BREVOC Study: Exhaled VOCs for High-Risk Chest Pain in the ED
Study Objectives 1. Screening and identification of diagnostic biomarkers: To establish the exhaled volatile organic compound (VOC) profile of patients with acute high-risk chest pain and to differentiate high-risk chest pain…
- Conditions
- Acute Coronary Syndrome, High-Risk Chest Pain, Volatile Organic Compounds
- Trial name
- BREVOC (NCT07379567)
- Testing
- observational study
- Volunteers
- 6,000 people
- Sponsor
- Qilu Hospital of Shandong University
Acute Ischemic Stroke Related to Tandem Occlusion, Acute Ischemic Stroke Due to Isolated Cervical Artery Occlusion
Risk Factors and Outcomes of Ischemic Stroke Associated With Tandem or Isolated Cervical Artery Occlusion in Anterior and Posterior Circulation
CERES-TANDEM is a multicenter study designed to improve the understanding of "tandem" ischemic stroke -those caused by two blockages in series, one in a neck artery and one in a brain artery-.
- Trial name
- CERES-TANDEM (NCT06965036)
- Where
- 3 sites in United States, Italy and 1 more
- Volunteers
- 4,230 people
- Sponsor
- Azienda Unità Sanitaria Locale della Romagna
Hypernatremia
ED Hypernatremia. Prognostic Factors and Epidemiology.
This study evaluate the 1-month mortality of patients who proceed a blood sample while in the ED with an hypernatremia (>145 mmol/l).
- Trial name
- NATSAU (NCT04265976)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon