Clinical trials: ED
HIV Counseling and Testing, HIV Infections
An Educational HIV Pre-Test Counseling Video Program for Off Hours Testing in the ED: A Randomized Control Trial
This study compared the educational effectiveness of a ten-minute pre-test counseling video with the usual practice of a session with an HIV counselor.
- Trial name
- NCT00218907
- Testing
- Educational video
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- North Bronx Healthcare Network
Mental Health Disorder, Mental and Behavioral Disorder
Outcomes in Youth Visiting the ED With Mental Health Issues: a Pilot Text Based Intervention
The investigators will conduct a prospective study and a randomized controlled trial (RCT) involving children and adolescents presenting with a primary mental health (MH) concern to the emergency departments (EDs) of Children's…
- Conditions
- Mental Health Disorder, Mental and Behavioral Disorder, Self-inflicted Injury
- Trial name
- NCT02744326
- Testing
- Text message reminders
- Volunteers
- 800 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Growth Failure, Intestinal Infection
MAL-ED Metabolic: A Follow-Up of Chronic Disease at Puberty
The concept that the roots of cardiometabolic disease start in early life was established by Dr. David Barker, who documented relationships between low birthweight (as a marker for challenges during gestation) and later…
- Conditions
- Growth Failure, Intestinal Infection, Metabolic Syndrome, Glucose Intolerance
- Trial name
- NCT05121935
- Volunteers
- 254 people
- Sponsor
- University of Virginia
Erectile Dysfunction
Intracavernous Injection of Botox 100 U for Treatment of PDE5Is Inconvenient Patients With ED
There is a new emerging concept that Botulinum Toxin Type A may have a potential role in treatment of erectile dysfunction with a longer duration of action.
- Trial name
- NCT04172558
- Testing
- OnabotulinumtoxinA, Trimix
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Benha University
Myocardial Infarction (MI), Chest Pain Rule Out Myocardial Infarction
The Rule-Out Acute Myocardial Infarction Using Aritifical Intelligence Electrocardiogram (ROMIAE) 2 Trial
This study is to see whether the AI ECG assisted protocol is as safe and efficacious as conventional protocol in early triage of suspected myocardial infarction.
- Trial name
- ROMIAE 2 (NCT07027891)
- Testing
- AI-ECG
- Where
- 12 sites in South Korea
- Volunteers
- 4,670 people
- Sponsor
- CHA University
Gastritis, Peptic Ulcer
H. Pylori Testing for Patients With Non-specific Upper Abdominal Pain in the Emergency Department
This pilot study aims to estimate the prevalence of Helicobacter pylori (H. pylori) colonization in patients presenting with non-specific abdominal pain (NSAP) in an urban academic emergency department (ED) located in Washington…
- Conditions
- Gastritis, Peptic Ulcer, Peptic Ulcer Perforation, Stomach Ulcer
- Trial name
- NCT01376414
- Testing
- Urea Breath Test (UBT) for H. pylori infection
- Where
- 2 sites in United States
- Volunteers
- 212 people
- Sponsor
- George Washington University
Oral Mucositis
Propolis-based Product (FARINGEL PLUS) for Oral Mucositis in Palliative Care
Oral health is crucial for palliative patients' quality of life. The evidence on effective interventions and measures of oral mucositis in palliative care is sparse.
- Trial name
- FARINGEL-CP (NCT04911335)
- Testing
- Faringel plus and oral hygiene
- Where
- Italy
- Volunteers
- 77 people
- Sponsor
- Campus Bio-Medico University
Asthma
Clinical, Airway Inflammatory, and HRA Phenotypes, in Preschool Children With Acute Asthmatic Attack Presenting to the ED.
Clinical, Airway Inflammatory, and HRA Phenotypes, in preschool children with acute asthmatic attack presenting to the ED. Background: Children under the age of 5 years have the highest hospitalization rate of asthma.
- Trial name
- NCT01175174
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Wolfson Medical Center
Emotional Disorders, Depression Anxiety Disorder
Cost-effectiveness and Implementation of a Transdiagnostic Internet-based Intervention for Emotional Disorders in Community Care.
Emotional disorders (ED) are one of the leading causes of disability. They are highly prevalent and have an impact on quality of life.
- Conditions
- Emotional Disorders, Depression Anxiety Disorder, Depression Disorders, Anxiety Disorders
- Trial name
- TREAT-ED (NCT07345117)
- Testing
- Internet-based psychological intervention, Treatment as usual (TAU)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Universitat Jaume I
Suicide
Ketamine & Crisis Response Plan for Suicidal Ideation in the ED
The goal of this randomized pilot trial is to assess the feasibility of administering a combination of 100mg intramuscular (IM) ketamine and Crisis Response Plan (a short psychosocial intervention) for patients with acute…
- Trial name
- NCT05696691
- Testing
- Ketamine Hydrochloride, Crisis Response Plan
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Renal Colic
Comparative Efficacy of IV Dexamethasone vs. Nebulized Terbutaline for Renal Colic Pain in the ED
Adult patients (18-55 years of age) with clinical diagnosis of acute renal colic (sudden sharp colic flank pain with or without radiation to genitalia or groin and with or without urinary symptoms) who had pain score of 5 or more…
- Trial name
- NCT06980727
- Testing
- Terbutaline 2.5 mg, Dexamethasone
- Where
- Tunisia
- Volunteers
- 500 people
- Sponsor
- University of Monastir
Respiratory Tract Infections
An Adjunct Test Distinguishing Bacterial From Viral Etiology Improves Resource Utilization and Efficiency in the ED.
The purpose of this study is to evaluate overall changes in patient management and longer-term resource utilization between control and test arms, including (but not limited to) additional work-up (including other diagnostic…
- Trial name
- NCT06070688
- Testing
- MeMed BV® biomarker test, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicidal Ideation, Suicide, Attempted
The Acceptability and Feasibility of an ED-based, Peer-delivered, Suicide Safety Planning Intervention
Safety planning is a brief, ED-feasible intervention which has been demonstrated to save lives, and has been universally recommended by every recent expert consensus panel on suicide prevention strategies.
- Conditions
- Suicidal Ideation, Suicide, Attempted, Mental Health Issue
- Trial name
- NCT04068142
- Testing
- Peer Supporter Safety Planning
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Arkansas
Pain, Acute
PENTHROX™ in the Canadian Emergency Department (ED)
This Canadian, multi-centre, prospective, real world study is designed to evaluate the effectiveness of low dose methoxyflurane (MEOF) (PENTHROX™) for the treatment of moderate to severe pain associated with trauma in the…
- Trial name
- ADVANCE-ED (NCT03868436)
- Testing
- Methoxyflurane 3mL
- Where
- 6 sites in Canada
- Volunteers
- 99 people
- Sponsor
- Purdue Pharma, Canada
Pain
A Comparison of Proprietary Formulations of Oral Ketamine + Aspirin and Oral Ketamine Alone for Musculoskeletal Pain
Acute Pain is one of the most frequent chief complaints and the main reason for visiting the Emergency Department (ED). The acute pain in the ED is largely prevalent across the country with recent literature demonstrating that…
- Trial name
- NCT04860804
- Testing
- Aspirin and Ketamine, Oral Ketamine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Antonios Likourezos
Microvascular Angina
Ranolazine and Microvascular Angina by PET in the Emergency Department
The purpose of this study is to determine the effectiveness of Ranolazine for the treatment chest pain from disease of small vessels of the heart also known as 'microvascular angina'.
- Trial name
- RAMP-ED (NCT02052011)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Yale University
Mental Disorder
Engaging Patients With Mental Disorders From the ED in Outpatient Care
This study will compare the effectiveness of professional and peer care managers in improving linkage to and engagement in outpatient care after an emergency department (ED) discharge, as well as the mechanisms by which…
- Trial name
- EPIC (NCT02989805)
- Testing
- Care Management
- Where
- United States
- Volunteers
- 326 people
- Sponsor
- Emory University
Acute Coronary Syndrome
Usefulness of a 2-hour Delta Troponin-I During the ED Identification and Exclusion of Acute Myocardial Infarction
1. In chest pain patients with suspected acute coronary syndrome, a 2-hr delta Troponin-I as measured by the i-STAT immunoassay reliably identifies and excludes an acute myocardial infarction. 2.
- Trial name
- NCT02002546
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Chattanooga-Hamilton County Hospital Authority
Back Pain
Erector Spinae Plane Block vs. Usual Care for ED Patients With Mechanical Back Pain
The goal of this clinical trial is to compare the Erector Spinae plane (ESP) block, a nerve block, to usual care in emergency department patients with back pain.
- Trial name
- NCT05982483
- Testing
- Erector Spinae plane block using 20 ml of bupivicaine 0.25%, Usual care
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Island Health
Sepsis, Septic Shock
Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients.
Infections in critically ill patients are a major healthcare problem and an important source of morbidity and mortality. Since critically ill patients often have altered pharmacokinetics (PK) compared to non-critically ill…
- Conditions
- Sepsis, Septic Shock, Infection, Bacterial, Critically Ill
- Trial name
- PHARAOH (NCT04470973)
- Testing
- Cefuroxime, Amikacin
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center