Clinical trials: ED
Mechanical Ventilation, Respiratory Failure
The Emergency Department Sedation Pilot Trial
The ED-SED Pilot is a multicenter, prospective, before-and-after study conducted on 344 mechanically ventilated emergency department patients at three academic medical centers: Washington University in St.
- Trial name
- ED SED Pilot (NCT04410783)
- Testing
- Education, Standard post intubation sedation practices
- Where
- 3 sites in United States
- Volunteers
- 1,771 people
- Sponsor
- Washington University School of Medicine
Asthma
Albuterol Versus Xopenex in Treatment of Acute Asthma in the Emergency Department (ED)
The purpose of this study is to determine in a large, double-blind, randomized, prospective pediatric clinical trial whether the use of continuous levalbuterol (Xopenex) in addition to standard emergency department treatment for…
- Trial name
- Xopenex (NCT00585039)
- Testing
- xopenex
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Phoenix Children's Hospital
Sepsis, Septic Shock
DIAGNOSis of Infection in Emergency Department
Septic pathology is an extremely frequent reason for consultation in our emergency services, with an annual incidence of severe forms between 50 to 95 cases per 100,000 inhabitants and a constant increase estimated at 9% per…
- Conditions
- Sepsis, Septic Shock, Sepsis, Severe, Infection
- Trial name
- DIAGNOSED (NCT03708796)
- Testing
- SIRS, qSOFA, NEWS, RETTS scores evaluation
- Where
- 7 sites in France
- Volunteers
- 759 people
- Sponsor
- Association pour la Formation l'Enseignement et la Recherche du Service de l'Accueil des Urgences
Asthma
Bi 671800 in Asthmatic Patients on Inhaled Corticosteroids
To investigate the effectiveness and safety of BI 671800 given in the morning (AM), evening (PM) or twice daily (b.i.d.) compared too placebo as add on therapy to inhaled corticosteroid in symptomatic asthma patients.
- Trial name
- NCT01090024
- Testing
- BI 671800
- Where
- 14 sites in United States
- Volunteers
- 108 people
- Sponsor
- Boehringer Ingelheim
Carbon Monoxide Poisoning
Suspected Cases of Carbon Monoxide Poisoning in the ED
The purpose of this study is to collect non-invasive observational data in suspected or known carbon monoxide poisoning.
- Trial name
- NCT03004235
- Testing
- Observational data collection
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Nonin Medical, Inc
Pain, Hip Fracture
PENG vs. FIC Block for Hip Fracture ED Patients
Ultrasound-guided nerve blocks are an important tool for treating pain due to orthopedic injury in the ED. They provide long lasting, opioid-sparing pain relief that is generally safe and well-tolerated by patients1.
- Trial name
- NCT05102760
- Testing
- Nerve Block using FIC Proceedure, Nerve Block using PENG Proceedure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Antonios Likourezos
Airway Management, Tracheal Intubation
Taiwan ED Airway Quality Surveillance Registry (TEAR)
This prospective, multicenter observational registry systematically captures all emergency department tracheal intubations across participating hospitals in Taiwan.
- Conditions
- Airway Management, Tracheal Intubation, Emergency Department, Peri-intubation Adverse Events
- Trial name
- NCT07574450
- Where
- Taiwan
- Volunteers
- 1,200 people
- Sponsor
- Chang Gung Memorial Hospital
Abdominal Pain Care
Improving Pain Management for Older Adults in the Emergency Department (ED)
The goals of this exploratory study are to determine the feasibility of integrating electronic clinical decision support into routine clinical pain care for adults in the ED setting and gather data on whether or not such clinical…
- Trial name
- NCT01962610
- Testing
- ePCA and Pain keycept intervention
- Where
- United States
- Volunteers
- 4,693 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hip Fractures, Delirium
ED Ultrasonographic Regional Anesthesia to Prevent Incident Delirium in Hip Fracture Patients
Hip fractures are common, costly and affect older people - Canadians spend 1 billion dollars to treat hip fractures each year. Unfortunately, as many as two-thirds of hip fracture cases suffer a complication known as delirium, or…
- Trial name
- EDU-RAPID (NCT02892968)
- Testing
- Fascia-Iliaca Block(FIB), Femoral Nerve Block(FNB)
- Where
- Canada
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Erectile Dysfunction, Impotence
PROPPER Prospective Registry of Outcomes With Penile Prosthesis
The purpose of this observational registry is to collect and better understand "real-world" outcomes for men undergoing penile implant surgery to treat erectile dysfunction.
- Trial name
- PROPPER (NCT01383018)
- Testing
- AMS Penile Prosthesis Devices
- Where
- 11 sites in United States, Canada
- Volunteers
- 1,457 people
- Sponsor
- Boston Scientific Corporation
Heart Failure
Accelerating Access and Improving Imaging in Heart Failure Care (A2I2HF) Pilot Study
This is a prospective, multicenter, cluster randomised trial which will assess the feasibility and acceptability of AI-assisted point of care echocardiography on HF detection and downstream care processes for patients with…
- Trial name
- NCT07624565
- Testing
- AI-assisted point-of-care ultrasound (POCUS)
- Volunteers
- 84 people
- Sponsor
- University of Alberta
Abdominal Pain, Thoracic Pain
PoCUS Impact on the Diagnostic Approach for Thoracic and Abdominal Pain in the ED
Many medical specialties and paramedical fields are increasingly using point-of-care ultrasound (PoCUS). In daily practice, thoracic and abdominal pain constitute a significant portion of emergency department consultations.
- Trial name
- DATAPUS (NCT06827730)
- Testing
- Point of care ultrasound
- Where
- Belgium
- Volunteers
- 406 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Renal Colic, Flank Pain
Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients
This is a prospective interventional study examining the effect of ketorolac at doses of 15mg versus 30 mg for duration of analgesia in emergency department patients with suspected renal colic.
- Conditions
- Renal Colic, Flank Pain, Emergencies, Analgesia
- Trial name
- NCT05776953
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Hackensack Meridian Health
Erectile Dysfunction
Clinical Trial of Low Intensity Shockwaves Therapy for Erectile Dysfunction Post-Radical Prostatectomy
Research study designed to learn about and compare Shockwave therapy (SWT) vs placebo (no shockwaves) treatment in men with moderate to severe erectile dysfunction (ED) after Radical Prostatectomy
- Trial name
- NCT06152146
- Testing
- Shockwave Therapy
- Where
- United States
- Sponsor
- University of Miami
Glioma, Glioma (Diagnosis)
AI-driven Processing and Analysis of Glioma Imaging Data
GLIOMAID is a scientific research project focused on improving how brain tumors, specifically gliomas, are diagnosed and managed. It uses Artificial Intelligence (AI) to analyze MRI brain scans and patient data.
- Trial name
- GLIOMAID (NCT07703761)
- Testing
- AI-driven analysis of brain MRI data for early, non-invasive detection, segmentation, and histological characterization of gliomas using retrospective clinical and imaging records.
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- Università degli Studi di Trento
Pediatric Uninsured Emergency Visits, Emergencies
ED Medicaid Support
The study introduces a bedside intervention assisting families with the enrollment or re-enrollment process through patient direct contact with NJFamily Care and financial departments, using an emergency department (ED)-based…
- Trial name
- NCT07594782
- Testing
- Navigation through financial systems and linkage to resources
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Abdominal Aortic Aneurism
Control Post Endovascular Treatment of Aortic Aneurisms Through Magnetic Resonance and Ultrasound (SAFEVAR)
The aims of this study are to verify non-inferiority of magnetic resonance (MR) without contrast agent associated to color-Doppler ultrasound for the diagnosis of endoleaks after endovascular aortic repair (EVAR), to evaluate…
- Trial name
- NCT03439423
- Testing
- CT with contrast agent, MR without contrast agent, Color-Doppler Ultrasound
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- IRCCS Policlinico S. Donato
Hyperkalemia
Patiromer Utility as an Adjunct Treatment in Patients Needing Urgent Hyperkalemia Management
When a patient arrives to an emergency department and is found to have an elevated potassium level in the blood, there is no one standardized treatment, therefore it is not known if one treatment is superior to other.
- Trial name
- PLATINUM (NCT04443608)
- Testing
- Patiromer Powder for Oral Suspension [Veltassa]
- Where
- 19 sites in United States
- Volunteers
- 115 people
- Sponsor
- Comprehensive Research Associates
Acute Coronary Syndrome
5th Generation cTnT in ED ACS
This study intends to investigate the usefulness of the new "5th generation" cardiac troponin enzyme in determining which patients presenting with possible acute coronary syndrome can be quickly and safely discharged or admitted…
- Trial name
- NCT03590535
- Testing
- 4th Gen cTnT, 5th Gen cTnT
- Where
- United States
- Volunteers
- 1,949 people
- Sponsor
- Columbia University
Erectile Dysfunction, Sexual Dysfunction, Physiological
Study to Compare the Tolerability and Efficacy of Once Daily Vardenafil vs Vardenafil PRN vs Placebo in Men Immediately After Nerve-sparing Prostatectomy for Improving ED
A study to assess the efficacy of vardenafil, taken as a tablet both nightly or 'as needed' (immediately before intended sexual activity) compared to placebo, to evaluate its tolerability and if it can help in recovery of…
- Trial name
- NCT00492635
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- 86 sites in United States, Austria and 13 more
- Volunteers
- 628 people
- Sponsor
- Bayer