Clinical trials: ED
Substance Withdrawal Syndrome
Utility of Olanzapine in the Treatment of Opioid Withdrawal in the ED
Withdrawal from opioids is a clinical scenario that emergency department physicians encounter frequently. Patients who present with opioid withdrawal display symptoms such as agitation, anxiety, myalgias, abdominal pain…
- Trial name
- NCT02643355
- Testing
- Olanzapine, Clonidine
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Pneumonia
Performance of New Diagnostic Methods in Older Adults With Pneumonia
Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy.
- Trial name
- PNEUMO (NCT06092008)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Ohio State University
Impotence, Erectile Dysfunction
Effect of Tadalafil on the Quality of Life and Sexual Life in Erectile Dysfunction
Study is a clinical study assessing the effect of oral tadalafil 10mg or 20 mg on psychosocial aspects and quality of life of erectile dysfunction patients and to compare tadalafil with previous oral erectile dysfunction…
- Trial name
- NCT00422578
- Testing
- tadalafil
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Eli Lilly and Company
Athlete, Sedentary Behavior
Health Parameters in Soccer Players and Sedentary Individuals After Consuming a Synbiotic
The main objective of this research was to carry out an experimental study, triple blind, on the possible immunophysiological effects of a nutritional supplement (Synbiotic, Gasteel Plus®, Heel España S.A.U.), containing a…
- Trial name
- NCT04776772
- Testing
- Synbiotic complement
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Catholic University of Murcia
Erectile Dysfunction, Peyronie's Disease
Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Peyronie's Disease, ED, and Interstitial Cystitis
This trial will study the safety and efficacy of intravenous and intracavernosal or interstitial delivery of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Peyronie's disease…
- Conditions
- Erectile Dysfunction, Peyronie's Disease, Interstitial Cystitis
- Trial name
- NCT05147779
- Testing
- AlloRx
- Where
- Antigua and Barbuda
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Sepsis
Pharmacokinetic/Pharmacodynamic Evaluation Amikacin in Critically Ill Patients Admitted at the Emergency Department
The aim of the study is the evaluation of PK/PD target attainment of amikacin in ED patients with severe sepsis and septic shock.
- Trial name
- NCT02365272
- Testing
- Amikacin
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Traumatic Brain Injury
Deployment of a Novel National Institute of Neurological Disorders and Stroke Clinical, Biomarker, Imaging, and Modifiers (CBI-M) Classification Framework for Emergency Department Patients With Glasgow Coma Scale 15 Traumatic Brain Injury (PIONEER-Prognosis)
This study is being done to learn how information from blood tests, medical records, and wearable devices that track sleep, activity, and heart rate can help predict how people recover after a concussion.
- Trial name
- NCT07858266
- Where
- 5 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Michigan
Pain, Acute, Dissociation
Low Dose Ketamine Infusion for Analgesia in the Emergency Department to Reduce Side Effects
This will be an intent to treat prospective, double blind, double-dummy, randomized trial. Our primary objective is the reduction of side effects of sub dissociative dose ketamine given by slow intravenous (IV) infusion over 30…
- Trial name
- NCT05518877
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Summa Health System
Erectile Dysfunction
Evaluating the Efficacy Vardenafil 10 mg vs Tadalafil 10 mg in in Subjects With Erectile Dysfunction (ED)
Evaluating the efficacy of 10mg vardenafil versus 10mg tadalafil in the first 45 minutes post-dosing, in an as-required regimen for 4 weeks in subjects with mild/moderate to severe ED
- Trial name
- NCT00663130
- Testing
- Levitra (Vardenafil, BAY38-9456), Tadalafil
- Volunteers
- 759 people
- Sponsor
- Bayer
Chest Pain
Chest Pain Triage at ED
CECIDOC is a prospective, monocentric and observational study comparing the diagnostic performance of ECG-base triage to a combination of ECG and cardiovascular risk factors for chest pain triage at ED.
- Trial name
- CECIDOC (NCT03913767)
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Université Catholique de Louvain
Small Cell Lung Cancer, Extensive-stage Small Cell Lung Cancer
Ipilimumab + Nivolumab w/Thoracic Radiotherapy for Extensive-Stage Small Cell Lung Cancer
The purpose of the safety run in Phase I portion of this study is to confirm the recommended Phase II dose of ipilimumab and nivolumab among participants treated with combined thoracic radiation therapy (30 Gy in 10 fractions)…
- Trial name
- NCT03043599
- Testing
- Thoracic Radiation Therapy, Ipilimumab, Nivolumab
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Attitudes About CT Utilization
Patient and Physician Attitudes About Informed Consent for Emergency Department (ED) Computerized Axial Tomography (CT) Scans
Hypothesis: The majority of Emergency physicians and patients do not feel that specific informed consent should be obtained for ED CT scans.
- Trial name
- CT Consent (NCT01174836)
- Testing
- Educational session
- Volunteers
- 77 people
- Sponsor
- Lehigh Valley Hospital
Prostatic Hyperplasia, Benign, Lower Urinary Tract Symptoms
Tadalafil Plus Tamsulosin for Male LUTS and ED
Metabolic Syndrome (MetS) is a complex epidemic disorder with an impact on both lower urinary tract symptoms (LUTS) and erectile dysfunction (ED).
- Conditions
- Prostatic Hyperplasia, Benign, Lower Urinary Tract Symptoms, Erectile Dysfunction, Metabolic Syndrome
- Trial name
- NCT04383093
- Testing
- Tadalafil 5mg
- Volunteers
- 75 people
- Sponsor
- University of Florence
Emergency Department Discharge Communication
Examining the Effectiveness and Implementation of the Emergency Department Patient-Activated Transition to Care At Home Tool
The goal of this clinical trial is to examine the effectiveness and implementation of the Emergency Department Patient-Activated Transition to Care at Home (ED-PATCH) tool, which is used by patients to manage information during…
- Trial name
- ED-PATCH (NCT06668636)
- Testing
- ED-PATCH
- Where
- 2 sites in Canada
- Volunteers
- 12,000 people
- Sponsor
- IWK Health Centre
Alcohol Abuse
Project Health Link: Connecting Patients With Services
This study will compare three alternative interventions in the emergency department (ED) to promote substance abuse assessment, referral, and treatment entry: 1) a 5 session strengths-based case management model (SBCM); 2) a…
- Trial name
- NCT00234221
- Testing
- Strengths Based Case Management, Motivational Enhancement Therapy, Brief Informational Feedback
- Where
- United States
- Volunteers
- 686 people
- Sponsor
- University of Michigan
Emergency Department Visit, Odontalgia
An Emergency Department (ED) Provider Centered Intervention for Non-Traumatic Dental Condition Management (NTDC)
The overall objective of this proposal is to understand the barriers and facilitators to non-traumatic dental condition (NTDC) management in the emergency department (ED) through quantitative and qualitative methods.
- Trial name
- NCT06330207
- Testing
- Clinical decision support tool
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Florida
Asthma
Pulmicort Respules on Relapse Rates After Treatment in the ED
The purpose of this study is to see if the addition of budesonide to oral corticosteroids will result in a decrease in relapse rates compared to oral corticosteroids alone in children who are discharged from the ED after an…
- Trial name
- Budesonide (NCT00584636)
- Testing
- pulmicort respules
- Where
- United States
- Sponsor
- Phoenix Children's Hospital
Sepsis, Septic Shock
Assessment of Heparin Binding Protein for the Prediction of Severe Sepsis
The purpose of this prospective, non-interventional, multi-centre clinical study is to assess the clinical validity of the Heparin Binding Protein (HBP) assay for indicating the presence, or outcome, of severe sepsis (including…
- Conditions
- Sepsis, Septic Shock, Sepsis With Acute Organ Dysfunction
- Trial name
- NCT03113721
- Where
- 5 sites in United States
- Volunteers
- 571 people
- Sponsor
- Axis Shield Diagnostics Ltd
Abscess
Adjunctive Nitrous Oxide During ED Incision and Drainage of Abscess
This study aims to describe the safety and efficacy of adjunctive nitrous oxide to lidocaine anesthesia in decreasing pain in adults during incision and drainage (I\&D) of cutaneous abscesses in the emergency department (ED).
- Trial name
- NCT03127371
- Testing
- Nitrous Oxide, Oxygen
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Albert Einstein Healthcare Network
Presyncope, Arrhythmias, Cardiac
The IPED (Investigation of Palpitations in the ED) Study
Palpitations (noticeable pounding, fluttering or irregular heart beat) and pre-syncope (near blackout) are common ED problems sometimes due to an abnormal cardiac rhythm.
- Conditions
- Presyncope, Arrhythmias, Cardiac, Tachycardia, Supraventricular, Atrial Fibrillation
- Trial name
- IPED (NCT02783898)
- Testing
- AliveCor Heart Monitor
- Where
- 10 sites in United Kingdom
- Volunteers
- 243 people
- Sponsor
- NHS Lothian