Clinical trials: ED
Lung Cancer
Sunitinib as a Second-line Treatment for Patients With Recurrent Small Cell Lung Cancer
the investigators will conduct a phase II trial to evaluate the efficacy and toxicity of Sunitinib in patients with recurrent SCLC.
- Trial name
- NCT00620347
- Testing
- sunitinib
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- National Cancer Center, Korea
Opioid-use Disorder, Emergency Department
Emergency Department Longitudinal Integrated Care
The overarching goal of this investigation is to develop and determine the feasibility of a multi-component intervention adapted from a collaborative care framework initiated in the ED for patients at risk for opioid use…
- Trial name
- ED-LINC (NCT03699085)
- Testing
- ED-LINC
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Asthma, Asthma Attack
ASTHMAXcel Emergency Department Study
This protocol focuses on Phase 1 of a planned two-phase research project. Phase 1 aims to test and adapt a prototype ASTHMAXcelED application for the ED.
- Trial name
- ASTHMAXcel (NCT05013073)
- Testing
- ASTHMAXcel ED Application
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Montefiore Medical Center
COVID-19
Risk Stratification of Patients With Suspected COVID-19 Presenting to the ED
Descriptive study of patients with suspected COVID-19 upon ED arrival of European hospitals between March 09 and April 08 2020. Justification:
- Trial name
- EuroCOV (NCT05465824)
- Where
- France
- Volunteers
- 7,876 people
- Sponsor
- University Hospital, Tours
Child Restraint Systems, Seat Belts
A Brief MI Intervention in the ED to Increase Child Passenger Restraint Use
This study involves an emergency department (ED)-based intervention utilizing Motivational Interviewing (MI) techniques and patient-centered (e.g., tailored) print materials to promote the correct and consistent use of…
- Trial name
- NCT02496481
- Testing
- Motivational Interviewing, Tailored brochure
- Where
- 2 sites in United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Benign Prostate Hyperplasia, Erectile Dysfunction
A Study of Tadalafil in Men With Benign Prostatic Hyperplasia (BPH) and Erectile Dysfunction (ED)
The purpose of this study is to see whether tadalafil can reduce the signs and symptoms in men with Erectile Dysfunction (ED) and Benign Prostatic Hyperplasia-Lower Urinary Tract Symptoms (BPH-LUTS) and improve their quality of…
- Trial name
- NCT01937871
- Testing
- 5 mg Tadalafil, 0.2 mg Tamsulosin
- Where
- 14 sites in China
- Volunteers
- 909 people
- Sponsor
- Eli Lilly and Company
Erectile Dysfunction
Study the Effect of Avanafil on the Pharmacodynamics and Pharmacokinetics of Warfarin in Healthy Male Subjects
This study is designed to look into the effect of avanafil on blood levels of warfarin and to investigate its effect on prothrombin time/international normalized ratio (INR) in healthy men.
- Trial name
- NCT01095588
- Testing
- 200 mg Avanafil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Evaluation of Video Discharge Instructions in Improving Understanding
Caregivers' Knowledge of Emergency Department Discharge Instructions Improves With the Use of Video
Previous studies demonstrate that patients often have difficulty understanding their discharge instructions. Video discharge instructions have the potential to mitigate factors such as illiteracy and limited physician time, which…
- Trial name
- NCT01630265
- Testing
- Standard written discharge instructions, Video Discharge Instructions
- Where
- United States
- Volunteers
- 436 people
- Sponsor
- Augusta University
Erectile Dysfunction
Clinical Trial of Topically-applied Glyceryl Trinitrate (GTN) for the Treatment of Erectile Dysfunction (ED)
This study is designed to evaluate the efficacy and safety of MED2005, a topically applied glyceryl trinitrate (GTN) gel administered to the penis of male subjects self-diagnosed with erectile dysfunction (ED) immediately before…
- Trial name
- NCT02495467
- Testing
- Glyceryl trinitrate
- Where
- United Kingdom
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Futura Medical Developments Ltd.
Headache, Migraine Disorders
IV Haloperidol for the Treatment of Headache in the ED
Single center, double-blind, randomized, placebo-controlled trial evaluating analog pain scores in patients who present to the emergency department (ED) with a complaint of headache.
- Trial name
- NCT02747511
- Testing
- Haloperidol
- Volunteers
- 118 people
- Sponsor
- Western Michigan University School of Medicine
Opioid Overdose Prevention, HIV Prevention and Care
Prevention and Rapid Outreach for Treatment, Engagement, and Care Transition From the Emergency Department
The Prevention and Rapid Outreach for Treatment, Engagement, and Care Transition from the Emergency Department (PROTECT-ED) study evaluates an emergency department-based implementation strategy designed to improve delivery of…
- Conditions
- Opioid Overdose Prevention, HIV Prevention and Care, Harm Reduction
- Trial name
- PROTECT-ED (NCT07868393)
- Testing
- PROTECT-ED Care Coordination
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Patients Presenting With Suspicion of Infection to the ED
Identifying Patients With Suspicion of Infection in the ED Who Have Low Disease Severity Using MR-proADM - Pilot Study
Emergency departments (ED) are becoming increasingly over-crowded, with patients facing prolonged waiting times. Therefore, a safe and rapid assessment that identifies patients with low severity that could be treated as…
- Trial name
- IDEAL (NCT03770533)
- Testing
- MR-proADM guided
- Where
- 4 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Brahms AG
Acute Pain
Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe Pain
Patients treated with protocolized pain management (1 mg of IV hydromorphone followed by an additional 1 mg IV hydromorphone if the patient wants more) will have better pain relief and no more adverse events than patients…
- Trial name
- NCT00627367
- Testing
- Hydromorphone, Nonprotocolized
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Frailty, Aged
Triage Assessment and NEWS-score as Risk Predictor in Older Frailty Adults in the ED
Emergency Department Triage Systems have not been shown to sufficiently recognize frail elderly patients in need of urgent assessment and care.
- Conditions
- Frailty, Aged, Triage
- Trial name
- NCT03783234
- Where
- Finland
- Volunteers
- 1,711 people
- Sponsor
- Helsinki University Central Hospital
Bronchiolitis
Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients
The purpose of this study is to assess whether children with moderate to severe bronchiolitis treated with standard racemic epinephrine therapy via 70:30 helium-oxygen (heliox) driven nebulization will have improvements in…
- Trial name
- NCT00116584
- Testing
- heliox, oxygen
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Erectile Dysfunction, Metabolic Syndrome
Study of Vardenafil in Patients Suffering From Erectile Dysfunction and Metabolic Syndrome
This is a controlled, randomized, multi-center prospective study of vardenafil to determine efficacy on Erectile Dysfunction (ED), tolerability and safety in men with ED and Metabolic Syndrome.
- Trial name
- NCT00738400
- Testing
- Vardenafil (Levitra, BAY38-9456)
- Where
- 19 sites in Germany
- Volunteers
- 150 people
- Sponsor
- Bayer
Pregnant Women
Estimation of the Effective Dose (ED) 95 of Intrathecal Hyperbaric Prilocaine 2% for Scheduled Cesarean Delivery.
Prilocaine is a local anesthetic drug which as an intermediate duration of action shorter than bupivacaine 0,5% that is usually used for spinal anesthesia in scheduled cesarean section.
- Trial name
- NCT03607916
- Testing
- Hyperbaric prilocaine 2%, Morphine
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Head Injury Other, Length of Stay
Severity Factors and Needed Observation Time at ED of Patients Wih Head Injury
We know precisely which patients and when they should have an imaging test to evaluate a Head Injury (HI). But in those patients on anticoagulant and / or antiaggregant treatment we do not know the exact incidence of early and…
- Conditions
- Head Injury Other, Length of Stay, Delayed Complications
- Trial name
- HESCTCE (NCT03970421)
- Testing
- Observation
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Hospital El Escorial
Pain
Effectiveness and Feasibility of Patient Controlled Analgesia in the ED
Background: Inadequate pain management is common in the Emergency Department (ED). Optimal treatment of pain necessitates titration to effective dose due to the large inter-individual variability in opioid requirement.
- Trial name
- NCT01775371
- Testing
- Patient controlled analgesia (PCA), Usual Care
- Where
- 3 sites in United States
- Volunteers
- 636 people
- Sponsor
- Albert Einstein College of Medicine
Unstable Angina, Non-ST-Elevation Myocardial Infarction
Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome.
The primary outcome in this study will be time to discharge for low-risk patients and therapeutic turnaround time for patients with NSTEMI or unstable angina.
- Trial name
- NCT00276432
- Testing
- iSTAT point of care analyzer
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Mayo Clinic