Clinical trials: EEG Brain Oscillations, active
Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic
Acoustic Stimulation During Sleep: Effects on Memory and p-tau217 in MCI
The goal of this clinical trial is to determine whether acoustic stimulation during sleep can enhance slow-wave sleep (SWS), improve cognitive function, and reduce AD-related pathology in individuals with mild cognitive…
- Conditions
- Alzheimer's Disease (AD), Mild Cognitive Impairment (MCI) Amnestic, Cognitively Unimpaired
- Trial name
- PAS-MCI (NCT07529015)
- Testing
- Plase-Locked Acoustic Stimulation during slow-wave sleep
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Institut de Recerca Biomèdica de Lleida-Fundació Dr. Pifarré (IRBLleida)
fMRI Research, Transcranial Magnetic Stimilation
The Relationships Between Neural Correlates of Effort Perception and Physical Activity Engagement
Objectives and research hypothesis Physical inactivity is a major health concern that has been linked to a variety of chronic diseases, including obesity, diabetes, cancer, cardiovascular diseases, and mental disorders.
- Conditions
- fMRI Research, Transcranial Magnetic Stimilation, EEG Brain Oscillations, Motor Task
- Trial name
- EffortLESS (NCT06691490)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Stroke, Upper Limb Function
Investigating the Effects of Transcranial Stimulation to Advance Stroke Rehabilitation
Non-invasive brain stimulation (NIBS) has the potential to boost rehabilitation after stroke by creating a 'pro-plastic' environment, where the brain is more adaptable in response to movement (motor) training.
- Trial name
- T-STAR (NCT06842095)
- Testing
- Transcranial Alternating Current Stimulation (beta-tACS)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Oxford
Cognitive Deficit
Studying the Effects of Brain Stimulation on Cognitive Control and Associated EEG in Human Subjects.
This is a basic neuroscience study of modulating brain oscillations involved in cognitive control. We will record brain signals and stimulate specific regions of the brain in human participants who are undergoing monitoring for…
- Trial name
- NCT05251454
- Testing
- Brain Stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Cincinnati
Schizophrenia
Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia
People with schizophrenia often have problems with attention, learning and memory and other cognitive abilities that interfere with their work and school performance.
- Trial name
- NCT04267003
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Gamma Oscillations, Healthy Adults
Investigating the Effectiveness of Personalized Optimal Gamma Auditory Frequency Stimulation Intervention on Cognitive Function Enhancement
This study aims to evaluate whether personalized gamma-frequency auditory stimulation enhances cognitive function and brain synchronization.
- Conditions
- Gamma Oscillations, Healthy Adults, Alzheimer's Disease (AD), Gamma Entrainment Using Sensory Stimuli (GENUS)
- Trial name
- NCT07690865
- Testing
- Personalized optimal gamma auditory frequency stimulation, Non-optimal gamma auditory frequency stimulation
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
EEG Brain Oscillations, Alzheimer's Disease (AD)
Effects of Endogenous Gamma Light Stimulation on Brain Oscillations in Cognitively-normal Older Adults
This study aims to evaluate the effects of endogenous gamma non-flickering light stimulation on resting-state EEG rhythms and cognitive function in cognitively healthy older adults.
- Conditions
- EEG Brain Oscillations, Alzheimer's Disease (AD), Cognitively Normal Older Adults
- Trial name
- NCT06715995
- Testing
- Gamma Wave Stimulation Table Lamp (Aleddra, Inc., USA)
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
EEG Brain Oscillations, Alzheimer's Disease (AD) and Related Disorders
Efficacy of Gamma Auditory Stimulation for Cognitive Decline in Older Adults (Study 1)
Animal studies have shown that 40 Hz auditory stimulation alone can improve spatial memory and reduce Aβ deposition. However, human studies using 40 Hz auditory stimulation alone remain limited.
- Conditions
- EEG Brain Oscillations, Alzheimer's Disease (AD) and Related Disorders, Cognitive Dysfunction
- Trial name
- NCT07087951
- Testing
- Gamma auditory stimulation device (active setting)
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Chang Gung Memorial Hospital
Stuttering, Adult, Stuttering, Childhood
Transcranial Alternating Current Stimulation (tACS) in Stuttering
The purpose of this study is to investigate how mild, noninvasive electrical brain stimulation affects speech relevant brain areas, which may in turn affect speech fluency and speaking-related brain activity in people that…
- Conditions
- Stuttering, Adult, Stuttering, Childhood, Stuttering, Developmental
- Trial name
- NCT06740968
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Major Depression, Sleep
Sleep TMS for Depression
The goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in depression treatment.
- Trial name
- NCT06824415
- Testing
- TMS
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive Compulsive Disorder (OCD), Treatment Resistant Obsessive Compulsive Disorder
Brain-Oscillation Synchronized Stimulation of the DMPFC
This trial aims to obtain initial evidence about the clinical efficacy and modulation of neurophysiological markers in obsessive compulsive disorder (OCD) using personalized (i.e., electroencephalography (EEG)-triggered)…
- Trial name
- BOSS-OCD (NCT06942559)
- Testing
- EEG-Triggered Repetitive Transcranial Magnetic Stimulation (rTMS), Non-EEG Triggered Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Centre for Addiction and Mental Health
Balance Assessment, Visuospatial/Perceptual Abilities
Relationship Between Visuospatial Attention and Balance
The term equilibrium is related to Newton's first law and, as used in mechanics, describes the state where the effect of the forces acting on an object is zero. Equilibrium is divided into two types: static and dynamic.
- Conditions
- Balance Assessment, Visuospatial/Perceptual Abilities, EEG Brain Oscillations
- Trial name
- NCT07714434
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul Gedik University
Stroke, Cerebrovascular Accident (CVA)
Investigating Central Contributions to Fatigue Using Non-invasive Brain Stimulation
The goal of this interventional study is to understand the contribution of the central components to the manifestation of neuromuscular fatigue in stroke survivors.
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Ischemia Stroke, Hemorrhage Stroke
- Trial name
- NCT07613970
- Testing
- Transcranial alternating current stimulation (tACS)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Ischemic Stroke, Acute
Brain-Oscillation-Synchronized Stimulation to Enhance Motor Recovery in Early Subacute Stroke
We will investigate the therapeutic efficacy of EEG-synchronized noninvasive repetitive transcranial magnetic stimulation (rTMS) in the early subacute phase after ischemic stroke to improve upper limb motor rehabilitation.
- Trial name
- Boss-Stroke (NCT05600374)
- Testing
- Bossdevice
- Where
- 4 sites in Germany
- Volunteers
- 144 people
- Sponsor
- University Hospital Tuebingen
Terminal Illness, End-of-Life Care
Non-Invasive Detection and Preservation of Neurocognitive Signals in the Peri-Death Period Using Brain-Computer Interface and Artificial Intelligence
Background: Recent electroencephalography (EEG) data indicate that the transition from clinical death to cellular death is marked by highly organized neurophysiological events, including significant surges in gamma-band power…
- Conditions
- Terminal Illness, End-of-Life Care, Death, Brain Death
- Trial name
- NeuroCogPresv (NCT07477028)
- Volunteers
- 20 people
- Sponsor
- Noah Tech, Corp.