Clinical trials: EGFR Inhibitor-associated Rash
EGFR Inhibitor-Induced Skin Rash
Prophylactic Treatment of Skin Rash Associated With EGFR Inhibitor Therapy
Epidermal growth factor receptor inhibitor (EGFRI) therapy for cancer is associated with potentially severe face and trunk skin acneiform rash.
- Trial name
- NCT04239846
- Testing
- AC-701 Topical Gel 0.3%
- Where
- 2 sites in Taiwan
- Volunteers
- 74 people
- Sponsor
- TWi Biotechnology, Inc.
EGFRI Induced Acneiform Lesions
LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC
The study evaluates the efficacy and safety of two strengths of LUT014 Gel topically applied once a day for 4 weeks, compared to placebo, in metastatic colorectal cancer (mCRC) patients who developed Grade 2 or non-infected Grade…
- Trial name
- NCT04759664
- Testing
- LUT014 Gel (Dose 1), LUT014 Gel (Dose 2)
- Where
- 20 sites in United States, Israel
- Volunteers
- 117 people
- Sponsor
- Lutris Pharma Ltd.
EGFR Inhibitor-associated Rash
A Study to Evaluate Topical ATR04-484 for EGFRi-Associated Dermal Toxicity
The goal of this randomized clinical trial is to learn if topical treatment with ATR04-484 can treat skin rash in patients undergoing EGFR inhibitor (EGFRi) therapy.
- Trial name
- NCT06830863
- Testing
- ATR04-484, Vehicle
- Where
- 6 sites in United States
- Volunteers
- 32 people
- Sponsor
- Azitra Inc.
EGFR Inhibitor-associated Rash
TAR-0520 Gel in EGFR Inhibitor-induced Folliculitis
A Phase II, multicentric, randomized, double-blind, placebo-controlled, parallel- group trial to confirm the good safaty profile and to explore the preventive effect of topically applied TAR-0520 gel on folliculitis developed in…
- Trial name
- NCT06818058
- Testing
- Brimonidine tartrate Gel
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- Tarian Pharma
EGFR Inhibitor-associated Rash
Safety, Tolerability and Systemic Absorption of Menadione Topical Lotion for Epidermal-Growth-Factor-Receptor (EGFR) Inhibitor-Associated Rash
This is a clinical research study of an experimental new medication, Menadione Topical Lotion (MTL). The study lotion is experimental and has not been approved for public use.
- Trial name
- NCT00656786
- Testing
- Menadione Topical Lotion
- Where
- 7 sites in United States, Canada
- Volunteers
- 18 people
- Sponsor
- Spectrum Pharmaceuticals, Inc