Clinical trials: ELDERLY PEOPLE
Dementia, Paratonia
Safety and Effectiveness of Botulinum Toxin in Elderly Patients With Dementia and Muscle Stiffness
Aim of the study is to perform a pilot study to assess the impact of Botulinum toxin on muscle tone, and caregiver burden in individuals who are cognitively impaired and who are fully dependent.
- Trial name
- NCT02212119
- Testing
- Botulinum Toxin, Saline
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Assistive Technology Clinic, Canada
Telemedicine
Medical Telemonitoring Plus Individual Teleconsultation in Elderly
The aim of this study is to explore the requirements and conditions of medical teleconsultation and remote diagnostics (telemonitoring) of older people in the residential environment with an emphasis on the need for adaptation…
- Trial name
- NCT02196428
- Testing
- Telemonitoring and Teleconsultation
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University of Zurich
Urinary Incontinence, Pelvic Floor Muscle Weakness
The Effects of Pelvic Floor Muscle Training Combined With Otago Exercises in Elderly People With Incontinence
Pelvic floor muscle weakness is one of the most important causes of incontinence. There are many studies supporting that pelvic floor muscle training prevents incontinence and reduces symptom severity, and with A level of…
- Conditions
- Urinary Incontinence, Pelvic Floor Muscle Weakness, Muscle Weakness
- Trial name
- NCT06331039
- Testing
- PFMT, PFMT+Otago
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Delirium Superimposed on Dementia
Delirium in Persons With Dementia
The aims of this study were to identify risk factors associated with delirium in hospitalized persons with dementia, and to describe immediate and post-hospital (1\&3 months) trajectory of cognitive decline and associated…
- Trial name
- NCT01394328
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Penn State University
Diabetes Mellitus
DiaFrail: A Short Duration Study in Older People ( DIAFRAIL Study)
1. Many patients with type 2 diabetes are not at glycaemic goal and require additional therapy in order to reduce vascular risk and improve symptom control 2.
- Trial name
- DiaFrail (NCT02484209)
- Testing
- Metformin, Glimepiride
- Sponsor
- Diabetes Frail Ltd
Healthy Aged Volunteers
The Influence of Different Types of Physical Exercise on Immunosenescence in Elderly Persons
This study aims to identify the mechanisms by which physical exercise can counter inflammation and improve immune function in older persons.
- Trial name
- NCT04534049
- Testing
- Intensive Strength Training (IST), Strength Endurance Training (SET), Flexibility Training (FT)
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Cognition, Anxiety
Biopsychosocial Effects of Gardening Activities
Due to the increasing number of elderly population worldwide, elderly care is becoming increasingly important and the number of elderly in institutional care is increasing.
- Conditions
- Cognition, Anxiety, Depression, Life Satisfaction
- Trial name
- NCT06844084
- Testing
- Gardening Activity
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Ordu University
Muscle Weakness
Effects of Simultaneous Balance and Resistance Training in Older Adults
Aging results in a gradual decline of physical abilities and consequently in functional impairments which increases the risk of falls in elderly people.
- Trial name
- NCT02555033
- Testing
- Resistance training, Instability resistance training
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Kassel
Hip Fracture, Vitamin D Deficiency
The Effect of Supplementation of Vitamin D Deficiency in Older People With Acute Hip Fracture:
This study will be done to evaluate the effect of load dose of vitamin D compared to the dose of usual clinical practice, in improving mobility and reducing disability in older people following a hip fracture.
- Trial name
- VITAMINA_D (NCT03213886)
- Testing
- Calcifediol (Vitamin D)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Leonor Cuadra Llopart
Muscle Weakness Condition, Therapy Effect
Vibrational-proprioceptive Resistance Exercise Training Versus Neuromuscular Electrical Stimulation Training in Elderly People With Muscle Weakness
Study the structural behaviours of weak muscle of elderly and evaluate the efficiency of two different types of training.
- Trial name
- MOBIL (NCT01679977)
- Testing
- Vibrational-proprioceptive Resistance Exercise Training, Neuromuscular Electrical Stimulation Training
- Where
- 2 sites in Austria, Slovakia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation
Homes for the Aged, Intestinal Elimination
Stool Ritual: Impact on the Number of Nights Without Stools Among Dependent Residents in Institutions for Dependent Elderly People
As they age, the intestinal elimination function can be altered by external factors. Sleeping is also a vital need for maintaining health.
- Trial name
- RITUELIM (NCT03118401)
- Testing
- Ritual of stool, Usual practice
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Limoges
Cancer Abdomen, Elderly (People Aged 65 or More)
Functional Decline and Quality of Life After Gastrointestinal Cancer Surgery in Older Adults
This prospective cohort study will evaluate functional decline, health-related quality of life, and long-term oncological outcomes in adults aged 65 years and older undergoing curative-intent resective surgery for…
- Conditions
- Cancer Abdomen, Elderly (People Aged 65 or More), Quality of Life, Sarcopenia in Elderly
- Trial name
- NCT07412379
- Where
- Colombia
- Volunteers
- 590 people
- Sponsor
- Hospital Universitario Mayor Méderi
Acute Pneumonia, Elderly Person
Aspirin in Acute Pneumonia in the Elderly: a Multicenter, Double-blind, Randomized, Placebo-controlled Trial.
Acute pneumonia is a very common disease, and one of the leading causes of hospitalization and death in France. Almost a century after the discovery of penicillin, no major breakthrough has significantly reduced pneumonia-related…
- Trial name
- ASPAPY (NCT06774846)
- Testing
- Acetylsalicylic acid/Aspirin (100 mg)
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Aging
Active Life Engagement in Relation to Health-related Outcomes Among Community-dwelling Chinese Older Adults
This study aims to examine within-person variations of different contexts (time, physical, psychosocial and affective) of active life engagement, and how these variations predict a set of physiological indicators and…
- Trial name
- NCT03518580
- Testing
- real-time assessment of biopsychosocial functioning
- Where
- Hong Kong
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Frailty, Frailty Syndrome
Characterising Frailty Using Magnetic Resonance Imaging
Ageing is associated with the development of various negative conditions, such as frailty. Defined as a decreased ability to combat negative stressors (e.g.
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome
- Trial name
- PHENOFRIM (NCT04612686)
- Where
- United Kingdom
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Dementia, Horticultural Therapy
The Effect of Horticultural Activities on Physical and Cognitive Status, Mental Well-Being, Social Participation and Quality of Life in Individuals Diagnosed with Dementia
This study aims to examine the effects of horticultural activities on the physical and cognitive status, mental well-being, social participation, and quality of life of individuals diagnosed with dementia living in nursing homes.
- Conditions
- Dementia, Horticultural Therapy, Quality of Life, Occupational Therapy
- Trial name
- NCT06899256
- Testing
- Horticultural Activity Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Influenza, Human, Influenza, Human Prevention
Phase III Clinical Trial of Quadrivalent Influenza Virus Split Vaccine
This is a randomized, blinded, active-controlled phase III clinical trial to evaluate the immunogenicity and safety of the Quadrivalent Influenza Virus Split Vaccine (QIV) in subjects (aged 3 years and above).
- Conditions
- Influenza, Human, Influenza, Human Prevention, Influenza a, Influenza B
- Trial name
- NCT06800950
- Testing
- QIV, QIV Control
- Where
- 3 sites in China
- Volunteers
- 4,400 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Chronic Pain
Nature as a Buffer Among People With Chronic Pain
This randomized controlled trial examines the effect of nature exposure on pain intensity levels among older adults who experience chronic pain.
- Trial name
- NCT03153891
- Testing
- Natural Environment, Built Environment
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Cornell University
Vitamin D Deficiency
Safety of Vitamin D Supplementation in Older Persons
This study will evaluate the safety over 6 months of two different doses of vitamin D (cholecalciferol) in men and women age 65 and older. It will also evaluate if supplementation with vitamin D improves physical performance.
- Trial name
- NCT00681590
- Testing
- cholecalciferol (vitamin D)
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Miami
Aging, Emergency Room
Robustness Predictive Factors in People Aged Over 75 Years After Going to the Emergency Room (ROB-U)
After emergency room visits, the elderly patients can increase their dependence and functional decline. In this context the goal of this study is to demonstrate that there are robustness predictive factors after visit to the…
- Conditions
- Aging, Emergency Room, Risk Factors
- Trial name
- ROB-U (NCT04683380)
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Lille Catholic University